451MO Final results of glasdegib in combination with temozolomide and radiotherapy in patients with newly diagnosed glioblastoma: Phase Ib/II GEINO 1602 trial von Salgado, M.A. Vaz, Barco, S. del, Sepúlveda, J.M., Alonso, M., Pineda, E., Balana, C., Martínez-García, M., Gironés, R., López-Muñoz, S.

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513P Cyclin pathway in oligodendrogliomas IDH mut and 1p/19q codeleted von Salgado, M.A. Vaz, Sanchez, J.M. Sepulveda, Earl, J., Perez, A., Pian, H., Ruano, Y., Gutierrez, J., Mena, A. Carrato, Ley, L.L., Villamayor, M., López, V., Delfrade, I. Martínez, Albarrán, V., Chamorro-Perez, J., Rodriguez, D.I. Rosero, Morón, B.I., A.H. lain

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479P Survival outcomes of resected gastroesophageal cancer and impact of active surveillance: Experience from a tertiary centre von Chamorro-Perez, J., González Martín, G., Corral de la Fuente, E., Albarrán Fernández, V., Rosero Rodriguez, D.I., San Roman Gil, M.V.V., Ferreiro Monteagudo, R., Martínez Delfrade, I., Morón, B.I., de Frutos González, B., Reguera Puertas, P., Serrano Domingo, J.J., Vaz Salgado, M.A., Villamayor Delgado, M.L., Guillen Ponce, C., Lopez Gomez, V., Rodriguez, M., Carrato Mena, A., Garrido Lopez, P., Longo Muñoz, F.

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500O Trotabresib (CC-90010) combined with concomitant temozolomide (TMZ) plus radiotherapy (RT) and adjuvant TMZ in patients (pts) with newly diagnosed primary glioblastoma (ndGBM)... von Villar, M. Vieito, Sánchez, J.M. Sepúlveda, Garcia, V. Moreno, Lombardi, G., Stradella, A., Dahlrot, R.H., Haslund, C.A., Geurts, M., Pineda, E., Brandal, P., De Vos, F.Y.F.L., Vaz Salgado, M.A., Garcia, M. Martinez, Macchini, M., Amoroso, B., Sanchez, T., Hanna, B., Li, X., Nikolova, Z., Simonelli, M.

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503MO Real-world clinical and genomic characterization of gliomas: Predictive and prognostic insights von Mirallas, O., Velilla, G., Ruiz-Pace, F., Yaringaño, J.G., Gorria, T., Gomez-Puerto, D., Martínez, Á., Valbuena, D.E. López, Vaz Salgado, M.A., Gonzalez, A. Hernandez, Sorolla, M. Aguado, Raskina, K., Rodriguez, M. Gonzalez, Garcia, M. Martinez, Galceran, J. Carles, Balana, C., Pineda, E., Dienstmann, R., Sánchez, J.M. Sepúlveda, Villar, M. Vieito

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533P Oligodendrogliomas: What is the impact after the introduction of the WHO molecular classification? von Salgado, M.A. Vaz, Earl, J., Sanchez, J.M. Sepulveda, Ruano, Y., Gutierrez, J., Pian, H., Ley, L.L., Delgado, M.L. Villamayor, Mena, A. Carrato, Fernandez, E., Martin, M., Monteagudo, R. Ferreiro, Muñoz, F. Longo, Rodriguez, M., Albarrán, V., Perez, J. Pozas, Ballesteros, P. Alvarez, San Roman Gil, M.V., A.H. lain

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106P Pharmacogenetic profiling in osteosarcoma to predict response and toxicity to neoadjuvant MAP: A study from the GEIS 33 protocol von Garcia, A. Sebio, Martin-Broto, J., Sirvent, F.J. Bautista, Martinez-Garcia, J., Trufero, J. Martinez, Insua, Y. Vidal, Barona, A. Echevarria, Beveridge, R.P. Diaz, Morales, C.M. Valverde, Luna Fra, P., Vaz Salgado, M.A., Albors, P.M. Blay, Alvarez, R.M., Salazar, J.

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43P MDM2 alterations in primary brain tumors: A potential niche for targeted therapy von Puerto, D.A. Gomez, Mirallas, O., Velilla, G., Cerna, J.G. Yaringaño, Ruiz-Pace, F., Gonzalez, A. Hernandez, Valbuena, D.E. López, Gorria, T., Vaz Salgado, M.A., Vinolas, M. Domenech, Sorolla, M. Aguado, Rodriguez, M. Gonzalez, Castro-Henriques Pinto-Machado, M., Garcia, M. Martinez, Dienstmann, R., Pineda, E., Galceran, J. Carles, Balana, C., Sanchez, J.M. Sepulveda, Villar, M. Vieito

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452MO Early experience with azeliragon, a RAGE inhibitor, in combination with temozolomide and radiotherapy in patients with newly diagnosed glioblastoma: Phase Ib/II CAN-201 NDG t... von Pineda, E., Sepúlveda, J.M., Valiente, M., Vaz-Salgado, M.Á., Martínez-García, M., Vico, M. Ruiz, Velilla, G., Mazariegos-Rubi, M.A., Valduvieco, I., Castro-Henriques, M., Cano, L., Marcus, S.G.

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SEOM clinical guidelines for diagnosis and treatment of glioblastoma (2017) von Martínez-García, Maria, Álvarez-Linera, Juan, Carrato, Cristina, Ley, L, Luque, Raquel, Maldonado, X, Martínez-Aguillo, M, Navarro, L.M, Vaz-Salgado, M.A, Gil-Gil, Miguel J

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457P Progression-free survival 2 (PFS2) as a surrogate for overall survival in a multicentric real-world data cohort of glioblastoma (GBM) von Cerna, J.G. Yaringaño, Mirallas, O., Puerto, D.A. Gomez, Velilla, G., Garces, V. Navarro, Puga, T. Gorría, Monino, A.M., Vaz-Salgado, M.Á., Lopez-Valbuena, D., Gonzalez, A. Hernandez, Sorolla, M. Aguado, Rodriguez, M. Gonzalez, Martínez-García, M., Galceran, J.C., Balana, C., Villacampa, G., Dienstmann, R., Pineda, E., Sepúlveda, J.M., Vieito, M.

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309P Patients with relapsed adult medulloblastoma (MB) treated by the GEINO (Spanish cooperative group for research in neuro-oncology) group oncologists: Natural history and patter... von Vieito Villar, M., Luque Caro, R., Martín Soberon, M.C., Del Barco Berron, S., Pineda, E., Vaz Salgado, M.Á., Tuñon, M.T., Herrero Ibañez, A., Quintanar Verduguez, T., Diaz Santos, J., Girones Sarrio, R.

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344MO Experience of GEINO (Spanish cooperative group for research in neuro-oncology) oncologists in the management of adult medulloblastoma von Vieito Villar, M., Luque Caro, R., Martin Soberon, M.C., Herrero Ibañez, A., Girones Sarrio, R., Luque Caro, N., Alonso Garcia, M., Quintanar Verduguez, T., del Barco Berrón, S., Moya Horno, I., Tuñón Cabeza, M.T., Gallego, O., de las Peñas, R., Vaz Salgado, M.Á., Ceballos Lenza, I., Cunquero-Tomás, A.J., Peralta Muñoz, S., Gutierrez Toribio, M., Diaz Santos, J.

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1069P A multicenter phase II study of nivolumab combined with ipilimumab in patients with pediatric solid tumours in adulthood (GETHI021) von Rubio, X. Mielgo, Diaz-Beveritge, R., Sanchez, J.M. Sepulveda, Pineda, E., Salgado, M.Á. Vaz, Lecumberri, M.J., Valverde, C., Castro, R. Lopez, López, C., Echaburu, J.A. Virizuela, Salas, N. Rodriguez, Bataller, R. de las Penas, Lopez, R. Lopez, Rodriguez, J. Medina, Rodriguez-Antona, C., Berraondo, P., Rodriguez-Moreno, J.F., Nuño, A. Hurtado, Sevillano, E., Garcia-Donas, J.

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Spanish survey of treatment recommendations for elderly patients with glioblastoma von Vaz Salgado, M Á, Rodríguez Sánchez, Á, Fernandez Perez, I., Quintanar, T., Navarro Martin, M., Vieito Villar, M., Cano, J.M., Gonzalez, S., Ros, S., Herrero Ibañez, A., Ivars, M.A., Lloret, M., Alonso, M., Moya, I., Luque, R., Benavides, M., Gutiérrez Toribio, M., García-Gómez, J., Esteban Villarrubia, J., Torres Jimenez, J.

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411P - Spanish survey of treatment recommendations for elderly patients with glioblastoma von Vaz Salgado, M Á, Rodríguez Sánchez, Á, Fernandez Perez, I., Quintanar, T., Navarro Martin, M., Vieito Villar, M., Cano, J.M., Gonzalez, S., Ros, S., Herrero Ibañez, A., Ivars, M.A., Lloret, M., Alonso, M., Moya, I., Luque, R., Benavides, M., Gutiérrez Toribio, M., García-Gómez, J., Esteban Villarrubia, J., Torres Jimenez, J.

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Analysis of Group B Streptococcal Isolates from Infants and Pregnant Women in Portugal Revealing Two Lineages with Enhanced Invasiveness von Martins, E.R, Pessanha, M.A, Ramirez, M, Melo-Cristino, J

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