Multiple BH3 Mimetics Antagonize Antiapoptotic MCL1 Protein by Inducing the Endoplasmic Reticulum Stress Response and Up-regulating BH3-only Protein NOXA von Albershardt, Tina C., Salerni, Bethany L., Soderquist, Ryan S., Bates, Darcy J.P., Pletnev, Alexandre A., Kisselev, Alexei F., Eastman, Alan

Volltext

Vinblastine sensitizes leukemia cells to cyclin-dependent kinase inhibitors, inducing acute cell cycle phase-independent apoptosis von Bates, Darcy J.P., Salerni, Bethany L., Lowrey, Christopher H., Eastman, Alan

Volltext

Vinblastine induces acute, cell cycle phase-independent apoptosis in some leukemias and lymphomas and can induce acute apoptosis in others when Mcl-1 is suppressed von Salerni, Bethany L, Bates, Darcy J, Albershardt, Tina C, Lowrey, Christopher H, Eastman, Alan

Volltext

Abstract 5477: Multiple BH3 mimetics antagonize anti-apoptotic MCL1 by inducing the endoplasmic reticulum stress response and upregulating the BH3-only protein NOXA von Albershardt, Tina C., Salerni, Bethany L., Soderquist, Ryan S., Bates, Darcy J P, Pletnev, Alexandre A., Eastman, Alan R.

Volltext