ClpP Protease, a Promising Antimicrobial Target von Moreno-Cinos, Carlos, Goossens, Kenneth, Salado, Irene G, Van Der Veken, Pieter, De Winter, Hans, Augustyns, Koen

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Protein Kinase CK‑1 Inhibitors As New Potential Drugs for Amyotrophic Lateral Sclerosis von Salado, Irene G, Redondo, Miriam, Bello, Murilo L, Perez, Concepción, Liachko, Nicole F, Kraemer, Brian C, Miguel, Laetitia, Lecourtois, Magalie, Gil, Carmen, Martinez, Ana, Perez, Daniel I

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To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A? von Zheng, Yang, Schroeder, Susanne, Kanev, Georgi K, Botros, Sanaa S, William, Samia, Sabra, Abdel-Nasser A, Maes, Louis, Caljon, Guy, Gil, Carmen, Martinez, Ana, Salado, Irene G, Augustyns, Koen, Edink, Ewald, Sijm, Maarten, de Heuvel, Erik, de Esch, Iwan J P, van der Meer, Tiffany, Siderius, Marco, Sterk, Geert Jan, Brown, David, Leurs, Rob

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Biological and Pharmacological Characterization of Benzothiazole-Based CK-1δ Inhibitors in Models of Parkinson’s Disease von Morales-Garcia, José A, Salado, Irene G, Sanz-San Cristobal, Marina, Gil, Carmen, Pérez-Castillo, Ana, Martínez, Ana, Pérez, Daniel I

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Screening of a PDE-focused library identifies imidazoles with in vitro and in vivo antischistosomal activity von Botros, Sanaa S., William, Samia, Sabra, Abdel-Nasser A., El-Lakkany, Naglaa M., Seif el-Din, Sayed H., García-Rubia, Alfonso, Sebastián-Pérez, Victor, Blaazer, Antoni R., de Heuvel, Erik, Sijm, Maarten, Zheng, Yang, Salado, Irene G., Munday, Jane C., Maes, Louis, de Esch, Iwan J.P., Sterk, Geert J., Augustyns, Koen, Leurs, Rob, Gil, Carmen, De Koning, Harry P.

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Novel triazine dimers with potent antitrypanosomal activity von Venkatraj, Muthusamy, Salado, Irene G., Heeres, Jan, Joossens, Jurgen, Lewi, Paul J., Caljon, Guy, Maes, Louis, Van der Veken, Pieter, Augustyns, Koen

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α‑Amino Diphenyl Phosphonates as Novel Inhibitors of Escherichia coli ClpP Protease von Moreno-Cinos, Carlos, Sassetti, Elisa, Salado, Irene G, Witt, Gesa, Benramdane, Siham, Reinhardt, Laura, Cruz, Cristina D, Joossens, Jurgen, Van der Veken, Pieter, Brötz-Oesterhelt, Heike, Tammela, Päivi, Winterhalter, Mathias, Gribbon, Philip, Windshügel, Björn, Augustyns, Koen

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Lead Optimization of Phthalazinone Phosphodiesterase Inhibitors as Novel Antitrypanosomal Compounds von Salado, Irene G, Singh, Abhimanyu K, Moreno-Cinos, Carlos, Sakaine, Guna, Siderius, Marco, Van der Veken, Pieter, Matheeussen, An, van der Meer, Tiffany, Sadek, Payman, Gul, Sheraz, Maes, Louis, Sterk, Geert-Jan, Leurs, Rob, Brown, David, Augustyns, Koen

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Leucine rich repeat kinase 2 (LRRK2) inhibitors based on indolinone scaffold: Potential pro-neurogenic agents von Salado, Irene G., Zaldivar-Diez, Josefa, Sebastián-Pérez, Víctor, Li, Lingling, Geiger, Larissa, González, Silvia, Campillo, Nuria E., Gil, Carmen, Morales, Aixa V., Perez, Daniel I., Martinez, Ana

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Evaluation of phthalazinone phosphodiesterase inhibitors with improved activity and selectivity against Trypanosoma cruzi von De Araújo, Julianna Siciliano, da Silva, Patrícia Bernardino, Batista, Marcos Meuser, Peres, Raiza Brandão, Cardoso-Santos, Camila, Kalejaiye, Titilola D, Munday, Jane C, De Heuvel, Erik, Sterk, Geert Jan, Augustyns, Koen, Salado, Irene G, Matheeussen, An, De Esch, Iwan, De Koning, Harry P, Leurs, Rob, Maes, Louis, Soeiro, Maria de Nazaré Correia

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Targeting TDP-43 phosphorylation by Casein Kinase-1δ inhibitors: a novel strategy for the treatment of frontotemporal dementia von Alquezar, Carolina, Salado, Irene G, de la Encarnación, Ana, Pérez, Daniel I, Moreno, Fermín, Gil, Carmen, de Munain, Adolfo López, Martínez, Ana, Martín-Requero, Ángeles

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Optimization of the pharmacokinetic properties of potent anti-trypanosomal triazine derivatives von Salado, Irene G., Baán, Adrienn, Verdeyen, Tomas, Matheeussen, An, Caljon, Guy, Van der Veken, Pieter, Kiekens, Filip, Maes, Louis, Augustyns, Koen

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Pharmacological tools based on imidazole scaffold proved the utility of PDE10A inhibitors for Parkinson's disease von García, Ana M, Salado, Irene G, Perez, Daniel I, Brea, José, Morales-García, Jose A, González-García, Alejandro, Cadavid, María Isabel, Loza, María Isabel, Luque, Francisco Javier, Perez-Castillo, Ana, Martinez, Ana, Gil, Carmen

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Evaluation of the effect of compound aqueous solubility in cytochrome P450 inhibition assays von Pérez, José, Díaz, Caridad, Salado, Irene G., Pérez, Daniel I., Peláez, Fernando, Genilloud, Olga, Vicente, Francisca

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To Target or Not to Target ISchistosoma mansoni/I Cyclic Nucleotide Phosphodiesterase 4A? von Zheng, Yang, Schroeder, Susanne, Kanev, Georgi K, Botros, Sanaa S, William, Samia, Sabra, Abdel-Nasser A, Maes, Louis, Caljon, Guy, Gil, Carmen, Ma, Salado, Irene G, Augustyns, Koen, Edink, Ewald, Sijm, Maarten, de Heuvel, Erik, de Esch, Iwan J. P, van der Meer, Tiffany, Siderius, Marco, Sterk, Geert Jan, Brown, David, Leurs, Rob

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Lead Optimization of Phthalazinone Phosphodiesterase Inhibitors as Novel Antitrypanosomal Compounds von Salado, Irene G, Singh, Abhimanyu K, Moreno-Cinos, Carlos, Sakaine, Guna, Siderius, Marco, Van der Veken, Pieter, Matheeussen, An, van der Meer, Tiffany, Sadek, Payman, Gul, Sheraz, Maes, Louis, Sterk, Geert-Jan, Leurs, Rob, Brown, David, Augustyns, Koen

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ChemInform Abstract: Regioselective 1,6-Conjugate Addition of Boronic Acids and Grignard Reagents to Dienylpyridines von Roscales, Silvia, Salado, Irene G., Csaky, Aurelio G.

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Targeting TDP-43 phosphorylation by Casein Kinase-1Delta inhibitors: a novel strategy for the treatment of frontotemporal dementia von Alquezar, Carolina, Salado, Irene G, de la Encarnacion, Ana, Perez, Daniel I, Moreno, Fermin, Gil, Carmen, Adolfo Lopez de Munain, Martinez, Ana, Martin-Requero, Angeles

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