FOXO3A as a key molecule for all-trans retinoic acid–induced granulocytic differentiation and apoptosis in acute promyelocytic leukemia von Sakoe, Yasuhiko, Sakoe, Kumi, Kirito, Keita, Ozawa, Keiya, Komatsu, Norio

Volltext

A newly identified NES sequence present in spastin regulates its subcellular localization and microtubule severing activity von Sakoe, Kumi, Shioda, Norifumi, Matsuura, Tohru

Volltext

Inhibition of hypoxia-inducible factor-1 function enhances the sensitivity of multiple myeloma cells to melphalan von Hu, Yongzhen, Kirito, Keita, Yoshida, Kozue, Mitsumori, Toru, Nakajima, Kei, Nozaki, Yumi, Hamanaka, Satoshi, Nagashima, Takahiro, Kunitama, Masae, Sakoe, Kumi, Komatsu, Norio

Volltext

Adult-onset Alexander disease with typical "tadpole" brainstem atrophy and unusual bilateral basal ganglia involvement: a case report and review of the literature von Namekawa, Michito, Takiyama, Yoshihisa, Honda, Junko, Shimazaki, Haruo, Sakoe, Kumi, Nakano, Imaharu

Volltext

Impact of Protein Phosphatase PP2A on ATRA-Induced Activation of FoxO3a In Acute Promyelocytic Leukemia Cells von Sakoe, Yasuhiko, Sakoe, Kumi, Shimazaki, Haruo, Kirito, Keita, Komatsu, Norio

Volltext

Middle Cerebellar Peduncles and Pontine T2 Hypointensities in ARSACS von Shimazaki, Haruo, Takiyama, Yoshihisa, Honda, Junko, Sakoe, Kumi, Namekawa, Michito, Tsugawa, Jun, Tsuboi, Yoshio, Suzuki, Chieko, Baba, Masayuki, Nakano, Imaharu

Volltext

A homozygous mutation of C12orf65 causes spastic paraplegia with optic atrophy and neuropathy (SPG55) von Shimazaki, Haruo, Takiyama, Yoshihisa, Ishiura, Hiroyuki, Sakai, Chika, Matsushima, Yuichi, Hatakeyama, Hideyuki, Honda, Junko, Sakoe, Kumi, Naoi, Tametou, Namekawa, Michito, Fukuda, Yoko, Takahashi, Yuji, Goto, Jun, Tsuji, Shoji, Goto, Yu-ichi, Nakano, Imaharu

Volltext

A novel RUNX1 mutation in familial platelet disorder with propensity to develop myeloid malignancies von KIRITO, Keita, SAKOE, Kumi, SHINODA, Daisuke, TAKIYAMA, Yoshihisa, KAUSHANSKY, Kenneth, KOMAISU, Norio

Volltext

Identification of GFAP gene mutation in hereditary adult-onset Alexander's disease von Namekawa, Michito, Takiyama, Yoshihisa, Aoki, Yoko, Takayashiki, Norio, Sakoe, Kumi, Shimazaki, Haruo, Taguchi, Tomohiro, Tanaka, Yasufumi, Nishizawa, Masatoyo, Saito, Ken, Matsubara, Yoichi, Nakano, Imaharu

Volltext

NF-κB mediates aberrant activation of HIF-1 in malignant lymphoma von Qiao, Qiao, Nozaki, Yumi, Sakoe, Kumi, Komatsu, Norio, Kirito, Keita

Volltext

A novel adult case of juvenile-onset Alexander disease: complete remission of neurological symptoms for over 12 years, despite insidiously progressive cervicomedullary atrophy von Namekawa, Michito, Takiyama, Yoshihisa, Honda, Junko, Sakoe, Kumi, Naoi, Tametou, Shimazaki, Haruo, Yamagata, Takanori, Momoi, Mariko Y., Nakano, Imaharu

Volltext

An unusual case of a spasticity-lacking phenotype with a novel SACS mutation von Shimazaki, Haruo, Sakoe, Kumi, Niijima, Kenji, Nakano, Imaharu, Takiyama, Yoshihisa

Volltext

A novel adult case of juvenile-onset Alexander disease: complete remission of neurological symptoms for over 12 years, despite insidiously progressive cervicomedullary atrophy von Namekawa, Michito, Takiyama, Yoshihisa, Honda, Junko, Sakoe, Kumi, Naoi, Tametou, Shimazaki, Haruo, Yamagata, Takanori, Momoi, Mariko Y., Nakano, Imaharu

Volltext

HIF-1 Prevents Hematopoietic Cells from Cell Damage by Overproduction of Mitochondrial ROS after Cytokine Stimulation through Induction of PDK-1 von Kirito, Keita, Yoshida, Kozue, Hu, Yongzhen, Qiao, Qiao, Sakoe, Kumi, Komatsu, Norio

Volltext

HIF-1 Supports the Survival of Multiple Myeloma Cells through the Induction of Survivin Gene von Kirito, Keita, Yongzhen, Hu, Yoshida, Kozue, Mitsumori, Toru, Nakajima, Kei, Nozaki, Yumi, Nagashima, Takahiro, Kunitama, Masae, Sakoe, Kumi, Komatsu, Norio

Volltext

Expression of Differentiation-Related Phenotypes and Apoptosis Are Independently Regulated during Myeloid Cell Differentiation von Terui, Yasuhito, Furukawa, Yusuke, Sakoe, Kumi, Ohta, Masatsugu, Saito, Masaki

Volltext

Expression Cloning and Functional Characterization of Human cDNA for Ganglioside GM3 Synthase von Ishii, Atsushi, Ohta, Masatsugu, Watanabe, Yumiko, Matsuda, Kazuhiro, Ishiyama, Keiko, Sakoe, Kumi, Nakamura, Mitsuru, Inokuchi, Jin-ichi, Sanai, Yutaka, Saito, Masaki

Volltext

A large Japanese SPG4 family with a novel insertion mutation of the SPG4 gene: a clinical and genetic study von Namekawa, Michito, Takiyama, Yoshihisa, Sakoe, Kumi, Shimazaki, Haruo, Amaike, Miho, Niijima, Kenji, Nakano, Imaharu, Nishizawa, Masatoyo

Volltext

Meiotic instability of the CAG repeats in the SCA6/CACNA1A gene in two Japanese SCA6 families von Shimazaki, Haruo, Takiyama, Yoshihisa, Sakoe, Kumi, Amaike, Miho, Nagaki, Hiromi, Namekawa, Michito, Sasaki, Hidenao, Nakano, Imaharu, Nishizawa, Masatoyo

Volltext

A Japanese family with spinocerebellar ataxia type 6 which includes three individuals homozygous for an expanded CAG repeat in the SCA6/CACNL1A4 gene von Takiyama, Yoshihisa, Sakoe, Kumi, Namekawa, Michito, Soutome, Michiyo, Esumi, Eisaku, Ogawa, Tomoko, Ishikawa, Kin-ya, Mizusawa, Hidehiro, Nakano, Imaharu, Nishizawa, Masatoyo

Volltext