Update on Alzheimer's Disease Therapy and Prevention Strategies von Graham, W. Vallen, Bonito-Oliva, Alessandra, Sakmar, Thomas P

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CXC Chemokine Receptor 3 Alternative Splice Variants Selectively Activate Different Signaling Pathways von Berchiche, Yamina A, Sakmar, Thomas P

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Targeting of the pulmonary capillary vascular niche promotes lung alveolar repair and ameliorates fibrosis von Cao, Zhongwei, Lis, Raphael, Ginsberg, Michael, Chavez, Deebly, Shido, Koji, Rabbany, Sina Y, Fong, Guo-Hua, Sakmar, Thomas P, Rafii, Shahin, Ding, Bi-Sen

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Introduction: G-Protein Coupled Receptors von Sakmar, Thomas P

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Defeating Alzheimer's disease and other dementias: a priority for European science and society von Winblad, Bengt, Prof, Amouyel, Philippe, Prof, Andrieu, Sandrine, Prof, Ballard, Clive, Prof, Brayne, Carol, Prof, Brodaty, Henry, Prof, Cedazo-Minguez, Angel, PhD, Dubois, Bruno, Prof, Edvardsson, David, Prof, Feldman, Howard, Prof, Fratiglioni, Laura, Prof, Frisoni, Giovanni B, Prof, Gauthier, Serge, Prof, Georges, Jean, BA, Graff, Caroline, Prof, Iqbal, Khalid, Prof, Jessen, Frank, Prof, Johansson, Gunilla, Jönsson, Linus, MD, Kivipelto, Miia, Prof, Knapp, Martin, Prof, Mangialasche, Francesca, MD, Melis, René, PhD, Nordberg, Agneta, Prof, Rikkert, Marcel Olde, Prof, Qiu, Chengxuan, MD, Sakmar, Thomas P, Prof, Scheltens, Philip, Prof, Schneider, Lon S, Prof, Sperling, Reisa, Prof, Tjernberg, Lars O, PhD, Waldemar, Gunhild, Prof, Wimo, Anders, Prof, Zetterberg, Henrik, Prof

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Recurrent activating mutations of G-protein-coupled receptor CYSLTR2 in uveal melanoma von Moore, Amanda R, Ceraudo, Emilie, Sher, Jessica J, Guan, Youxin, Shoushtari, Alexander N, Chang, Matthew T, Zhang, Jenny Q, Walczak, Edward G, Kazmi, Manija A, Taylor, Barry S, Huber, Thomas, Chi, Ping, Sakmar, Thomas P, Chen, Yu

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A simple method for enhancing the bioorthogonality of cyclooctyne reagent von Tian, He, Sakmar, Thomas P, Huber, Thomas

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Elucidating the Interactome of G Protein-Coupled Receptors and Receptor Activity-Modifying Proteins von Kotliar, Ilana B, Lorenzen, Emily, Schwenk, Jochen M, Hay, Debbie L, Sakmar, Thomas P

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GPCRs globally coevolved with receptor activity-modifying proteins, RAMPs von Barbash, Shahar, Lorenzen, Emily, Persson, Torbjörn, Huber, Thomas, Sakmar, Thomas P.

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Playing Tag with Your Favorite GPCR Using CRISPR von Horioka, Mizuho, Huber, Thomas, Sakmar, Thomas P.

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The Energetics of Chromophore Binding in the Visual Photoreceptor Rhodopsin von Tian, He, Sakmar, Thomas P., Huber, Thomas

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Genetically encoded photocrosslinkers locate the high-affinity binding site of antidepressant drugs in the human serotonin transporter von Rannversson, Hafsteinn, Andersen, Jacob, Sørensen, Lena, Bang-Andersen, Benny, Park, Minyoung, Huber, Thomas, Sakmar, Thomas P., Strømgaard, Kristian

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Itch receptor MRGPRX4 interacts with the receptor activity–modifying proteins von Kotliar, Ilana B., Ceraudo, Emilie, Kemelmakher-Liben, Kevin, Oren, Deena A., Lorenzen, Emily, Dodig-Crnković, Tea, Horioka-Duplix, Mizuho, Huber, Thomas, Schwenk, Jochen M., Sakmar, Thomas P.

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Pharmacology: Inside-out receptor inhibition von Sakmar, Thomas P, Huber, Thomas

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Direct evidence that the GPCR CysLTR2 mutant causative of uveal melanoma is constitutively active with highly biased signaling von Ceraudo, Emilie, Horioka, Mizuho, Mattheisen, Jordan M., Hitchman, Tyler D., Moore, Amanda R., Kazmi, Manija A., Chi, Ping, Chen, Yu, Sakmar, Thomas P., Huber, Thomas

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14-3-3 signal adaptor and scaffold proteins mediate GPCR trafficking von Yuan, Luwa, Barbash, Shahar, Kongsamut, Sathapana, Eishingdrelo, Alex, Sakmar, Thomas P., Eishingdrelo, Haifeng

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Brain gene expression signature on primate genomic sequence evolution von Barbash, Shahar, Sakmar, Thomas P.

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Length-dependent gene misexpression is associated with Alzheimer’s disease progression von Barbash, Shahar, Sakmar, Thomas P.

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G protein subtype-specific signaling bias in a series of CCR5 chemokine analogs von Lorenzen, Emily, Ceraudo, Emilie, Berchiche, Yamina A, Rico, Carlos A, Fürstenberg, Alexandre, Sakmar, Thomas P, Huber, Thomas

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Genetic code expansion and photocross-linking identify different β-arrestin binding modes to the angiotensin II type 1 receptor von Gagnon, Laurence, Cao, Yubo, Cho, Aaron, Sedki, Dana, Huber, Thomas, Sakmar, Thomas P., Laporte, Stéphane A.

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