The Dual Roles of MYC in Genomic Instability and Cancer Chemoresistance von Kumari, Alpana, Folk, Watson P, Sakamuro, Daitoku

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Loss of the tumor suppressor BIN1 enables ATM Ser/Thr kinase activation by the nuclear protein E2F1 and renders cancer cells resistant to cisplatin von Folk, Watson P., Kumari, Alpana, Iwasaki, Tetsushi, Pyndiah, Slovénie, Johnson, Joanna C., Cassimere, Erica K., Abdulovic-Cui, Amy L., Sakamuro, Daitoku

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New Synthetic Lethality Re-Sensitizing Platinum-Refractory Cancer Cells to Cisplatin In Vitro: The Rationale to Co-Use PARP and ATM Inhibitors von Folk, Watson P., Kumari, Alpana, Iwasaki, Tetsushi, Cassimere, Erica K., Pyndiah, Slovenie, Martin, Elizabeth, Homlar, Kelly, Sakamuro, Daitoku

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c-MYC suppresses BIN1 to release poly(ADP-ribose) polymerase 1: a mechanism by which cancer cells acquire cisplatin resistance von Pyndiah, Slovénie, Tanida, Satoshi, Ahmed, Kazi M, Cassimere, Erica K, Choe, Chungyoul, Sakamuro, Daitoku

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Mechanisms of Cisplatin-Induced Apoptosis and of Cisplatin Sensitivity: Potential of BIN1 to Act as a Potent Predictor of Cisplatin Sensitivity in Gastric Cancer Treatment von Tanida, Satoshi, Mizoshita, Tsutomu, Ozeki, Keiji, Tsukamoto, Hironobu, Kamiya, Takeshi, Kataoka, Hiromi, Sakamuro, Daitoku, Joh, Takashi

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New Myc-interacting proteins: a second Myc network emerges von Sakamuro, D, Prendergast, G C

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The polyproline region of p53 is required to activate apoptosis but not growth arrest von SAKAMURO, D, SABBATINI, P, WHITE, E, PRENDERGAST, G. C

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Identification of a novel effector domain of BIN1 for cancer suppression von Lundgaard, Greta L., Daniels, Natae E., Pyndiah, Slovénie, Cassimere, Erica K., Ahmed, Kazi M., Rodrigue, Amélie, Kihara, Daisuke, Post, Carol B., Sakamuro, Daitoku

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Abstract B34: PD-0332991/palbociclib facilitates the physical interaction between RB1 and BIN1 to increase the vulnerability of pediatric osteosarcoma cells to PARP inhibition von Folk, Watson P., Homlar, Kelly, Sakamuro, Daitoku

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Adenovirus E1A oncoprotein liberates c-Myc activity to promote cell proliferation through abating Bin1 expression via an Rb/E2F1-dependent mechanism von Kinney, Erica L., Tanida, Satoshi, Rodrigue, Amelie A., Johnson, Joanna K., Tompkins, Van S., Sakamuro, Daitoku

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Bin1 functionally interacts with Myc and inhibits cell proliferation via multiple mechanisms von ELLIOTT, K, SAKAMURO, D, PRENDERGAST, G. C, BASU, A, WEI DU, WUNNER, W, STALLER, P, GAUBATZ, S, HONG ZHANG, PROCHOWNIK, E, EILERS, M

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Losses of the tumor suppressor BIN1 in breast carcinoma are frequent and reflect deficits in programmed cell death capacity von Ge, K, Duhadaway, J, Sakamuro, D, Wechsler-Reya, R, Reynolds, C, Prendergast, G C

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Bin1 attenuation in breast cancer is correlated to nodal metastasis and reduced survival von Ghaneie, Arezoo, Zemba-Palca, Vlasta, Itoh, Hiromichi, Itoh, Kaori, Sakamuro, Daitoku, Nakamura, Seigo, Peralta Soler, Alejandro, Prendergast, George C.

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Endocrine disruptor exposure during development increases incidence of uterine fibroids by altering DNA repair in myometrial stem cells von Fernung, Lauren E Prusinski, Yang, Qiwei, Sakamuro, Daitoku, Kumari, Alpana, Mas, Aymara, Al-Hendy, Ayman

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Functional and Transcriptional Interactions Between Regulator of G‐protein Signaling Protein 10 (RGS10) and Tumor Suppressor Proteins in Cancer Chemosensitization von Hooks, Shelley, Alqinyah, Mohammed, Webster, Andrew, Sakamuro, Daitoku

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Viral Particle-Mediated SAMHD1 Depletion Sensitizes Refractory Glioblastoma to DNA-Damaging Therapeutics by Impairing Homologous Recombination von Daddacha, Waaqo, Monroe, Dominique, Carver, Kristen, Usoro, Edidiong R, Alptekin, Ahmet, Xu, Hongyan, Osuka, Satoru, Arbab, Ali S, Sakamuro, Daitoku

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Abstract B03: Physical and functional interactions between two tumor suppressors, BIN1 and RB1 von Folk, Watson P., Kumari, Alpana, Cassimere, Erica, Johnson, Joanna, Sakamuro, Daitoku

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Protein-Mediated Interactions of Pancreatic Islet Cells von Meda, Paolo

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Abstract C297: PARP1 and BIN1 cooperate to act as a novel co-repressor for E2F1 von Kumari, Alpana, Pyndiah, Slovénie, Cassimere, Erica K., Sakamuro, Daitoku

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Abstract PR09: c-MYC preserves genomic integrity during DNA replication: a paradigm shift of c-MYC von Kumari, Alpana, Iwasaki, Tetsushi, Folk, Walson P., Abdulovic-Cui, Amy L., Pyndiah, Slovénie, Prendergast, George C., Sedivy, John M., Sakamuro, Daitoku

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