Molecular mechanisms underlying osteoarthritis development: Notch and NF-κB von Saito, Taku, Tanaka, Sakae

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Mechanisms of synovial joint and articular cartilage development von Chijimatsu, Ryota, Saito, Taku

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The superficial zone of articular cartilage von Saito, Taku

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Excessive mechanical loading promotes osteoarthritis through the gremlin-1–NF-κB pathway von Chang, Song Ho, Mori, Daisuke, Kobayashi, Hiroshi, Mori, Yoshifumi, Nakamoto, Hideki, Okada, Keita, Taniguchi, Yuki, Sugita, Shurei, Yano, Fumiko, Chung, Ung-il, Kim-Kaneyama, Joo-ri, Yanagita, Motoko, Economides, Aris, Canalis, Ernesto, Chen, Di, Tanaka, Sakae, Saito, Taku

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Pathomechanism of intervertebral disc degeneration von Oichi, Takeshi, Taniguchi, Yuki, Oshima, Yasushi, Tanaka, Sakae, Saito, Taku

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Loss of Mob1a/b in mice results in chondrodysplasia due to YAP1/TAZ-TEAD-dependent repression of SOX9 von Goto, Hiroki, Nishio, Miki, To, Yoko, Oishi, Tatsuya, Miyachi, Yosuke, Maehama, Tomohiko, Nishina, Hiroshi, Akiyama, Haruhiko, Mak, Tak Wah, Makii, Yuma, Saito, Taku, Yasoda, Akihiro, Tsumaki, Noriyuki, Suzuki, Akira

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Runx1 contributes to articular cartilage maintenance by enhancement of cartilage matrix production and suppression of hypertrophic differentiation von Yano, Fumiko, Ohba, Shinsuke, Murahashi, Yasutaka, Tanaka, Sakae, Saito, Taku, Chung, Ung-il

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Regulation of osteoarthritis development by ADAM17/Tace in articular cartilage von Kaneko, Taizo, Horiuchi, Keisuke, Chijimatsu, Ryota, Mori, Daisuke, Nagata, Kosei, Omata, Yasunori, Yano, Fumiko, Inui, Hiroshi, Moro, Toru, Tanaka, Sakae, Saito, Taku

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Runx2 and Runx3 differentially regulate articular chondrocytes during surgically induced osteoarthritis development von Nagata, Kosei, Hojo, Hironori, Chang, Song Ho, Okada, Hiroyuki, Yano, Fumiko, Chijimatsu, Ryota, Omata, Yasunori, Mori, Daisuke, Makii, Yuma, Kawata, Manabu, Kaneko, Taizo, Iwanaga, Yasuhide, Nakamoto, Hideki, Maenohara, Yuji, Tachibana, Naohiro, Ishikura, Hisatoshi, Higuchi, Junya, Taniguchi, Yuki, Ohba, Shinsuke, Chung, Ung-il, Tanaka, Sakae, Saito, Taku

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Biphasic regulation of chondrocytes by Rela through induction of anti-apoptotic and catabolic target genes von Kobayashi, Hiroshi, Chang, Song Ho, Mori, Daisuke, Itoh, Shozo, Hirata, Makoto, Hosaka, Yoko, Taniguchi, Yuki, Okada, Keita, Mori, Yoshifumi, Yano, Fumiko, Chung, Ung-il, Akiyama, Haruhiko, Kawaguchi, Hiroshi, Tanaka, Sakae, Saito, Taku

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Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone von Xuan, Fengjun, Yano, Fumiko, Mori, Daisuke, Chijimatsu, Ryota, Maenohara, Yuji, Nakamoto, Hideki, Mori, Yoshifumi, Makii, Yuma, Oichi, Takeshi, Taketo, Makoto Mark, Hojo, Hironori, Ohba, Shinsuke, Chung, Ung-Il, Tanaka, Sakae, Saito, Taku

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Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development von Hosaka, Yoko, Saito, Taku, Sugita, Shurei, Hikata, Tomohiro, Kobayashi, Hiroshi, Fukai, Atsushi, Taniguchi, Yuki, Hirata, Makoto, Akiyama, Haruhiko, Chung, Ung-il, Kawaguchi, Hiroshi

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Hypoxia-inducible factor-1 alpha maintains mouse articular cartilage through suppression of NF-κB signaling von Okada, Keita, Mori, Daisuke, Makii, Yuma, Nakamoto, Hideki, Murahashi, Yasutaka, Yano, Fumiko, Chang, Song Ho, Taniguchi, Yuki, Kobayashi, Hiroshi, Semba, Hiroaki, Takeda, Norihiko, Piao, Wen, Hanaoka, Kenjiro, Nagano, Tetsuo, Tanaka, Sakae, Saito, Taku

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Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment von Aini, Hailati, Itaka, Keiji, Fujisawa, Ayano, Uchida, Hirokuni, Uchida, Satoshi, Fukushima, Shigeto, Kataoka, Kazunori, Saito, Taku, Chung, Ung-il, Ohba, Shinsuke

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Baricitinib ameliorates inflammatory and neuropathic pain in collagen antibody-induced arthritis mice by modulating the IL-6/JAK/STAT3 pathway and CSF-1 expression in dorsal root g... von Makabe, Kenta, Okada, Hiroyuki, Tachibana, Naohiro, Ishikura, Hisatoshi, Ito, Norihito, Tanaka, Masaru, Chijimatsu, Ryota, Terashima, Asuka, Yano, Fumiko, Asaka, Meiko, Yanagihara, Dai, Taketomi, Shuji, Matsumoto, Takumi, Tanaka, Sakae, Omata, Yasunori, Saito, Taku

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Lubricin Contributes to Homeostasis of Articular Cartilage by Modulating Differentiation of Superficial Zone Cells von Maenohara, Yuji, Chijimatsu, Ryota, Tachibana, Naohiro, Uehara, Kosuke, Xuan, Fengjun, Mori, Daisuke, Murahashi, Yasutaka, Nakamoto, Hideki, Oichi, Takeshi, Chang, Song Ho, Matsumoto, Takumi, Omata, Yasunori, Yano, Fumiko, Tanaka, Sakae, Saito, Taku

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Evaluating the two‐item measure of engagement at work for Japan Self‐Defense Forces: A cross‐sectional study von Saito, Taku, Kitano, Masato, Waki, Fumiko, Nagamine, Masanori

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Ear Cartilage Reconstruction Combining Induced Pluripotent Stem Cell-Derived Cartilage and Three-Dimensional Shape-Memory Scaffold von Uto, Sakura, Hikita, Atsuhiko, Sakamoto, Tomoaki, Mori, Daisuke, Yano, Fumiko, Ohba, Shinsuke, Saito, Taku, Takato, Tsuyoshi, Hoshi, Kazuto

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The small compound, TD-198946, protects against intervertebral degeneration by enhancing glycosaminoglycan synthesis in nucleus pulposus cells von Kushioka, Junichi, Kaito, Takashi, Chijimatsu, Ryota, Okada, Rintaro, Ishiguro, Hiroyuki, Bal, Zeynep, Kodama, Joe, Yano, Fumiko, Saito, Taku, Chung, Ung-il, Tanaka, Sakae, Yoshikawa, Hideki

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Type 2 innate lymphoid cells inhibit the differentiation of osteoclasts and protect from ovariectomy-induced bone loss von Omata, Yasunori, Frech, Michael, Lucas, Sébastien, Primbs, Tatjana, Knipfer, Lisa, Wirtz, Stefan, Kadono, Yuho, Saito, Taku, Tanaka, Sakae, Sarter, Kerstin, Schett, Georg, Zaiss, Mario M.

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