Million Veteran Program: A mega-biobank to study genetic influences on health and disease von Gaziano, John Michael, Concato, John, Brophy, Mary, Fiore, Louis, Pyarajan, Saiju, Breeling, James, Whitbourne, Stacey, Deen, Jennifer, Shannon, Colleen, Humphries, Donald, Guarino, Peter, Aslan, Mihaela, Anderson, Daniel, LaFleur, Rene, Hammond, Timothy, Schaa, Kendra, Moser, Jennifer, Huang, Grant, Muralidhar, Sumitra, Przygodzki, Ronald, O'Leary, Timothy J

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Pharmacogenetic allele variant frequencies: An analysis of the VA's Million Veteran Program (MVP) as a representation of the diversity in US population von Markianos, Kyriacos, Dong, Frederic, Gorman, Bryan, Shi, Yunling, Dochtermann, Daniel, Saxena, Uma, Devineni, Poornima, Moser, Jennifer, Muralidhar, Sumitra, Ramoni, Rachel, Tsao, Philip, Pyarajan, Saiju, Przygodzki, Ronald

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Multi-ancestry GWAS meta-analyses of lung cancer reveal susceptibility loci and elucidate smoking-independent genetic risk von Gorman, Bryan R., Ji, Sun-Gou, Francis, Michael, Sendamarai, Anoop K., Shi, Yunling, Devineni, Poornima, Saxena, Uma, Partan, Elizabeth, DeVito, Andrea K., Byun, Jinyoung, Han, Younghun, Xiao, Xiangjun, Sin, Don D., Timens, Wim, Moser, Jennifer, Muralidhar, Sumitra, Ramoni, Rachel, Hung, Rayjean J., McKay, James D., Bossé, Yohan, Sun, Ryan, Amos, Christopher I., Pyarajan, Saiju

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Admixture mapping of peripheral artery disease in a Dominican population reveals a putative risk locus on 2q35 von Cullina, Sinead, Wojcik, Genevieve L, Shemirani, Ruhollah, Klarin, Derek, Gorman, Bryan R, Sorokin, Elena P, Gignoux, Christopher R, Belbin, Gillian M, Pyarajan, Saiju, Asgari, Samira, Tsao, Philip S, Damrauer, Scott M, Abul-Husn, Noura S, Kenny, Eimear E

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Modeling the longitudinal changes of ancestry diversity in the Million Veteran Program von Wendt, Frank R, Pathak, Gita A, Vahey, Jacqueline, Qin, Xuejun, Koller, Dora, Cabrera-Mendoza, Brenda, Haeny, Angela, Harrington, Kelly M, Rajeevan, Nallakkandi, Duong, Linh M, Levey, Daniel F, De Angelis, Flavio, De Lillo, Antonella, Bigdeli, Tim B, Pyarajan, Saiju, Gaziano, John Michael, Gelernter, Joel, Aslan, Mihaela, Provenzale, Dawn, Helmer, Drew A, Hauser, Elizabeth R, Polimanti, Renato

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Genome-wide Association Study of Intracranial Aneurysms Reveals Shared Heritability With Aortic Aneurysms and Atherosclerosis von Adkar, Shaunak, Lynch, Julie, Bamezai, Sharika, Sorondo, Sabina, Choi, Ryan, Levin, Michael, Damrauer, Scott M., Pyarajan, Saiju, Tsao, Philip S., Skirboll, Stephen, Leeper, Nick J., Klarin, Derek

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A multi-ancestry GWAS of Fuchs corneal dystrophy highlights the contributions of laminins, collagen, and endothelial cell regulation von Gorman, Bryan R., Francis, Michael, Nealon, Cari L., Halladay, Christopher W., Duro, Nalvi, Markianos, Kyriacos, Genovese, Giulio, Hysi, Pirro G., Choquet, Hélène, Afshari, Natalie A., Li, Yi-Ju, Gaziano, J. Michael, Hung, Adriana M., Wu, Wen-Chih, Greenberg, Paul B., Pyarajan, Saiju, Lass, Jonathan H., Peachey, Neal S., Iyengar, Sudha K.

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Gene-Toxicant Interactions in Gulf War Illness: Differential Effects of the PON1 Genotype von Vahey, Jacqueline, Gifford, Elizabeth J, Sims, Kellie J, Chesnut, Blair, Boyle, Stephen H, Stafford, Crystal, Upchurch, Julie, Stone, Annjanette, Pyarajan, Saiju, Efird, Jimmy T, Williams, Christina D, Hauser, Elizabeth R

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Prostaglandin E2 Activates HPK1 Kinase Activity via a PKA-dependent Pathway von Sawasdikosol, Sansana, Pyarajan, Saiju, Alzabin, Saba, Matejovic, Gabriel, Burakoff, Steven J.

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From bytes to bedside: data integration and computational biology for translational cancer research von Mathew, Jomol P, Taylor, Barry S, Bader, Gary D, Pyarajan, Saiju, Antoniotti, Marco, Chinnaiyan, Arul M, Sander, Chris, Burakoff, Steven J, Mishra, Bud

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With equal access, African American patients have superior survival compared to white patients with multiple myeloma: a VA study von Fillmore, Nathanael R., Yellapragada, Sarvari V., Ifeorah, Chizoba, Mehta, Ansh, Cirstea, Diana, White, Paul S., Rivero, Gustavo, Zimolzak, Andrew, Pyarajan, Saiju, Do, Nhan, Brophy, Mary, Munshi, Nikhil C.

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Genetic Architecture of Chronic Back Pain: A Multi-Ancestry Genome-Wide Association Study in The Million Veteran Program von Stanaway, Ian B., Suri, Pradeep, Afari, Niloofar, Dochtermann, Daniel, Pyarajan, Saiju, Roseen, Eric J., Gasperi, Marianna

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Genome-wide association study of post-traumatic stress disorder reexperiencing symptoms in >165,000 US veterans von Gelernter, Joel, Sun, Ning, Polimanti, Renato, Pietrzak, Robert, Levey, Daniel F., Bryois, Julien, Lu, Qiongshi, Hu, Yiming, Li, Boyang, Radhakrishnan, Krishnan, Aslan, Mihaela, Cheung, Kei-Hoi, Li, Yuli, Rajeevan, Nallakkandi, Sayward, Frederick, Harrington, Kelly, Chen, Quan, Cho, Kelly, Pyarajan, Saiju, Sullivan, Patrick F., Quaden, Rachel, Shi, Yunling, Hunter-Zinck, Haley, Gaziano, J. Michael, Concato, John, Zhao, Hongyu, Stein, Murray B.

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Genotyping Array Design and Data Quality Control in the Million Veteran Program von Hunter-Zinck, Haley, Shi, Yunling, Li, Man, Gorman, Bryan R., Ji, Sun-Gou, Sun, Ning, Webster, Teresa, Liem, Andrew, Hsieh, Paul, Devineni, Poornima, Karnam, Purushotham, Gong, Xin, Radhakrishnan, Lakshmi, Schmidt, Jeanette, Assimes, Themistocles L., Huang, Jie, Pan, Cuiping, Humphries, Donald, Brophy, Mary, Moser, Jennifer, Muralidhar, Sumitra, Huang, Grant D., Przygodzki, Ronald, Concato, John, Gaziano, John M., Gelernter, Joel, O’Donnell, Christopher J., Hauser, Elizabeth R., Zhao, Hongyu, O’Leary, Timothy J., Tsao, Philip S., Pyarajan, Saiju

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Mo1420 THE IMPACT OF PHENOTYPIC HETEROGENEITY ON GENOME WIDE ASSOCIATION STUDIES OF PANCREATIC DUCTAL ADENOCARCINOMA von Wang, Louise, Zhang, Chi, Larki, Navid Rahimi, Dochtermann, Daniel R., Pyarajan, Saiju, Dewan, Andrew, Voight, Ben, Kember, Rachel, Justice, Amy C., Zhao, Hongyu

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Genome-wide Association Study of Maximum Habitual Alcohol Intake in >140,000 U.S. European and African American Veterans Yields Novel Risk Loci von Gelernter, Joel, Sun, Ning, Polimanti, Renato, Pietrzak, Robert H., Levey, Daniel F., Lu, Qiongshi, Hu, Yiming, Li, Boyang, Radhakrishnan, Krishnan, Aslan, Mihaela, Cheung, Kei-Hoi, Li, Yuli, Rajeevan, Nallakkandi, Sayward, Fred, Harrington, Kelly, Chen, Quan, Cho, Kelly, Honerlaw, Jacqueline, Pyarajan, Saiju, Lencz, Todd, Quaden, Rachel, Shi, Yunling, Hunter-Zinck, Haley, Gaziano, J. Michael, Kranzler, Henry R., Concato, John, Zhao, Hongyu, Stein, Murray B.

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P515. Genomic Analyses of Schizophrenia and Bipolar Disorder Patients With Very Poor Outcomes von Harvey, Philip, Bigdeli, Tim, Fanous, Ayman, Rajeevan, Nallakkandi, Gorman, Bryan, Genovese, Giulio, Li, Yuli, Sayward, Frederick, Pyarajan, Saiju, Aslan, Mihaela

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Interleukin-3 (IL-3)-induced c-fos Activation Is Modulated by Gab2-Calcineurin Interaction von Pyarajan, Saiju, Matejovic, Gabriel, Pratt, Joanne C., Baksh, Shairaz, Burakoff, Steven J.

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Abstract 250: Genome-wide Association Study Of Intracranial Aneurysms Reveals Shared Heritability With Aortic Aneurysms And Atherosclerosis von Adkar, Shaunak, Lynch, Julie, Bamezai, Sharika, Sorondo, Sabina, Choi, Ryan, Levin, Michael, Damrauer, Scott M, Pyarajan, Saiju, Tsao, Philip S, Skirboll, Stephen, Leeper, Nick J, Klarin, Derek

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Pharmacogenetic allele variant frequencies: An analysis of the VA's Million Veteran Program von Markianos, Kyriacos, Dong, Frederic, Gorman, Bryan, Shi, Yunling, Dochtermann, Daniel, Saxena, Uma, Devineni, Poornima, Moser, Jennifer, Muralidhar, Sumitra, Ramoni, Rachel, Tsao, Philip, Pyarajan, Saiju, Przygodzki, Ronald

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