Suppression of c‐Myc using 10058‐F4 exerts caspase‐3‐dependent apoptosis and intensifies the antileukemic effect of vincristine in pre‐B acute lymphoblastic leukemia cells... von Sheikh‐Zeineddini, Negar, Bashash, Davood, Safaroghli‐Azar, Ava, Riyahi, Niknam, Shabestari, Rima Manafi, Janzamin, Ehsan, Safa, Majid

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The PI3K/Akt/mTORC signaling axis in head and neck squamous cell carcinoma: Possibilities for therapeutic interventions either as single agents or in combination with conventional... von Akbari Dilmaghani, Nader, Safaroghli‐Azar, Ava, Pourbagheri‐Sigaroodi, Atieh, Bashash, Davood

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Anti‐leukemic effect of PI3K inhibition on chronic myeloid leukemia (CML) cells: shedding new light on the mitigating effect of c‐Myc and autophagy on BKM120 cytotoxicity von Shiri Heris, Reza, Safaroghli‐Azar, Ava, Yousefi, Amir‐Mohammad, Hamidpour, Mohsen, Bashash, Davood

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The PI3K/Akt signaling axis in Alzheimer’s disease: a valuable target to stimulate or suppress? von Razani, Elham, Pourbagheri-Sigaroodi, Atieh, Safaroghli-Azar, Ava, Zoghi, Anahita, Shanaki-Bavarsad, Mahsa, Bashash, Davood

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PI3K Abrogation Using Pan-PI3K Inhibitor BKM120 Gives Rise to a Significant Anticancer Effect on AML-Derived KG-1 Cells by Inducing Apoptosis and G2/M Arrest von Sadeghi, Soroush, Esmaeili, Shadi, Pourbagheri-Sigaroodi, Atieh, Safaroghli-Azar, Ava, Bashash, Davood

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Small molecule inhibitor of c-Myc 10058-F4 inhibits proliferation and induces apoptosis in acute leukemia cells, irrespective of PTEN status von Bashash, Davood, Sayyadi, Mohamad, Safaroghli-Azar, Ava, Sheikh-Zeineddini, Negar, Riyahi, Niknam, Momeny, Majid

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Melatonin, an inhibitory agent in breast cancer von Nooshinfar, Elaheh, Safaroghli-Azar, Ava, Bashash, Davood, Akbari, Mohammad Esmaeil

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C-Myc inhibition sensitizes pre-B ALL cells to the anti-tumor effect of vincristine by altering apoptosis and autophagy: Proposing a probable mechanism of action for 10058-F4 von Sheikh‐Zeineddini, Negar, Safaroghli-azar, Ava, Salari, Sina, Bashash, Davood

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Stimulatory Effect of Indolic Hormone on As2O3 Cytotoxicity in Breast Cancer Cells: NF-κB-dependent Mechanism of Action of Melatonin von Safaroghli, Azar Ava, Atieh, Pourbagheri Sigaroodi, Bashash Davood, Nooshinfar Elaheh, Ali, Anjam-Najmedini, Sadeghi Soroush, Rezaie-Tavirani Mostafa, Akbari, Mohammad Esmaeil

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ZnO/CNT@Fe3O4 induces ROS-mediated apoptosis in chronic myeloid leukemia (CML) cells: an emerging prospective for nanoparticles in leukemia treatment von Yousefi, Amir-Mohammad, Safaroghli-Azar, Ava, Fakhroueian, Zahra, Bashash, Davood

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Evaluation of hTERT, KRT7, and survivin in urine for noninvasive detection of bladder cancer using real-time PCR von Yahyazadeh, Reza, Bashash, Davood, Ghaffari, Parisa, Kord, Saeid, Safaroghli-Azar, Ava, Ghaffari, Seyed H

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Apoptin Overexpression Efficiently Amplified Cytotoxic Effects of PI3K Inhibition Using BKM120 in Lymphoblastic Leukemia Cell Lines von Anjam-Najmedini, Ali, Vahabpour, Rohollah, Safaroghli-Azar, Ava, Kazemi, Alireza, Movahhed, Parvaneh, Momeny, Majid, Bashash, Davood

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Suppression of proteasome induces apoptosis in APL cells and increases chemo-sensitivity to arsenic trioxide: Proposing a perception in APL treatment von Zamani-Moghaddam, Nahid, Mousavi, Fahime S, Esmaeili, Shadi, Yousefi, Amir-Mohammad, Safaroghli-Azar, Ava, Bashash, Davood

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Cytotoxic Effect of Telomerase Catalytic (hTERT) and Nucleotide (hTERC) Subunit Inhibitors on Acute Promyelocytic Leukemia Cells von Atieh Pourbagheri-Sigaroodi, Ava Safaroghli-Azar, Fahimeh Nemati Mansoor, Davood Bashash

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Pan-HDAC inhibitor panobinostat, as a single agent or in combination with PI3K inhibitor, induces apoptosis in APL cells: An emerging approach to overcome MSC-induced resistance von Mosleh, Mohammad, Safaroghli-Azar, Ava, Bashash, Davood

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Phosphoinositide 3-kinase (PI3K) classes: From cell signaling to endocytic recycling and autophagy von Safaroghli-Azar, Ava, Sanaei, Mohammad-Javad, Pourbagheri-Sigaroodi, Atieh, Bashash, Davood

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Platelets in the perspective of COVID-19; pathophysiology of thrombocytopenia and its implication as prognostic and therapeutic opportunity von Delshad, Mahda, Safaroghli-Azar, Ava, Pourbagheri-Sigaroodi, Atieh, Poopak, Behzad, Shokouhi, Shervin, Bashash, Davood

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The contributory role of lymphocyte subsets, pathophysiology of lymphopenia and its implication as prognostic and therapeutic opportunity in COVID-19 von Delshad, Mahda, Tavakolinia, Naeimeh, Pourbagheri-Sigaroodi, Atieh, Safaroghli-Azar, Ava, Bagheri, Nader, Bashash, Davood

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The PI3K/Akt/mTOR signaling pathway in gastric cancer; from oncogenic variations to the possibilities for pharmacologic interventions von Baghery Saghchy Khorasani, Ayda, Pourbagheri-Sigaroodi, Atieh, Pirsalehi, Ali, Safaroghli-azar, Ava, Zali, Mohammad Reza, Bashash, Davood

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Kinase inhibitors: Opportunities for small molecule anticancer immunotherapies von Safaroghli-Azar, Ava, Emadi, Fatemeh, Lenjisa, Jimma, Mekonnen, Laychiluh, Wang, Shudong

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