Genome-wide CRISPR screen identifies genes synthetically lethal with GRA17, a nutrient channel encoding gene in Toxoplasma von Paredes-Santos, Tatiana C, Bitew, Mebratu A, Swale, Christopher, Rodriguez, Felipe, Krishnamurthy, Shruthi, Wang, Yifan, Maru, Parag, Sangaré, Lamba Omar, Saeij, Jeroen P J

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Toxoplasma GRA15 and GRA24 are important activators of the host innate immune response in the absence of TLR11 von Mukhopadhyay, Debanjan, Arranz-Solis, David, Saeij, Jeroen P. J.

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Polymorphic Secreted Kinases Are Key Virulence Factors in Toxoplasmosis von Saeij, J. P. J., Boyle, J. P., Coller, S., Taylor, S., Sibley, L. D., Brooke-Powell, E. T., Ajioka, J. W., Boothroyd, J. C.

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Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence von Reese, Michael L, Zeiner, Gusti M, Saeij, Jeroen P.J, Boothroyd, John C, Boyle, Jon P

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The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response von Niedelman, Wendy, Gold, Daniel A, Rosowski, Emily E, Sprokholt, Joris K, Lim, Daniel, Farid Arenas, Ailan, Melo, Mariane B, Spooner, Eric, Yaffe, Michael B, Saeij, Jeroen P J

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The human immune response to Toxoplasma: Autophagy versus cell death von Krishnamurthy, Shruthi, Konstantinou, Eleni K, Young, Lucy H, Gold, Daniel A, Saeij, Jeroen P J

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Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue von Boothroyd, J. C, Saeij, J. P. J, Coller, S, Boyle, J. P, Jerome, M. E, White, M. W

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Toxoplasma gondii effectors are master regulators of the inflammatory response von Melo, Mariane B, Jensen, Kirk D.C, Saeij, Jeroen P.J

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Cell Death of Gamma Interferon-Stimulated Human Fibroblasts upon Toxoplasma gondii Infection Induces Early Parasite Egress and Limits Parasite Replication von Niedelman, Wendy, Sprokholt, Joris K, Clough, Barbara, Frickel, Eva-Maria, Saeij, Jeroen P J

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Toxoplasma gondii Matrix Antigen 1 Is a Secreted Immunomodulatory Effector von Tomita, Tadakimi, Mukhopadhyay, Debanjan, Han, Bing, Yakubu, Rama, Tu, Vincent, Mayoral, Joshua, Sugi, Tatsuki, Ma, Yanfen, Saeij, Jeroen P. J., Weiss, Louis M.

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Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it von Virreira Winter, Sebastian, Niedelman, Wendy, Jensen, Kirk D, Rosowski, Emily E, Julien, Lindsay, Spooner, Eric, Caradonna, Kacey, Burleigh, Barbara A, Saeij, Jeroen P J, Ploegh, Hidde L, Frickel, Eva-Maria

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Influence of the Host and Parasite Strain on the Immune Response During Toxoplasma Infection von Mukhopadhyay, Debanjan, Arranz-Solis, David, Saeij, Jeroen P. J.

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Admixture and recombination among Toxoplasma gondii lineages explain global genome diversity von Minot, Samuel, Melo, Mariane B, Li, Fugen, Lu, Diana, Niedelman, Wendy, Levine, Stuart S, Saeij, Jeroen P. J

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Toxoplasma gondii Rhoptry 16 Kinase Promotes Host Resistance to Oral Infection and Intestinal Inflammation Only in the Context of the Dense Granule Protein GRA15 von Jensen, Kirk D C, Hu, Kenneth, Whitmarsh, Ryan J, Hassan, Musa A, Julien, Lindsay, Lu, Diana, Chen, Lieping, Hunter, Christopher A, Saeij, Jeroen P J

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Inflammasome sensor NLRP1 controls rat macrophage susceptibility to Toxoplasma gondii von Cirelli, Kimberly M, Gorfu, Gezahegn, Hassan, Musa A, Printz, Morton, Crown, Devorah, Leppla, Stephen H, Grigg, Michael E, Saeij, Jeroen P J, Moayeri, Mahtab

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Genome-wide screens identify Toxoplasma gondii determinants of parasite fitness in IFNγ-activated murine macrophages von Wang, Yifan, Sangaré, Lamba Omar, Paredes-Santos, Tatiana C., Hassan, Musa A., Krishnamurthy, Shruthi, Furuta, Anna M., Markus, Benedikt M., Lourido, Sebastian, Saeij, Jeroen P. J.

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Toxoplasma gondii Inhibits Gamma Interferon (IFN-γ)- and IFN-β-Induced Host Cell STAT1 Transcriptional Activity by Increasing the Association of STAT1 with DNA von Rosowski, Emily E, Nguyen, Quynh P, Camejo, Ana, Spooner, Eric, Saeij, Jeroen P J

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The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages von ten Hoeve, Arne L., Braun, Laurence, Rodriguez, Matias E., Olivera, Gabriela C., Bougdour, Alexandre, Belmudes, Lucid, Couté, Yohann, Saeij, Jeroen P.J., Hakimi, Mohamed-Ali, Barragan, Antonio

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Bioluminescence Imaging of Toxoplasma gondii Infection in Living Mice Reveals Dramatic Differences between Strains von Saeij, Jeroen P. J, Boyle, Jon P, Grigg, Michael E, Arrizabalaga, Gustavo, Boothroyd, John C

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The Toxoplasma Polymorphic Effector GRA15 Mediates Seizure Induction by Modulating Interleukin-1 Signaling in the Brain von Glausen, Taylor G., Carrillo, Gabriela L., Jin, Richard M., Boyle, Jon P., Saeij, Jeroen P. J., Wohlfert, Elizabeth A., Fox, Michael A., Blader, Ira J.

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