Quantifying the role of transcript levels in mediating DNA methylation effects on complex traits and diseases von Sadler, Marie C., Auwerx, Chiara, Lepik, Kaido, Porcu, Eleonora, Kutalik, Zoltán

Volltext

Breaking down causes, consequences, and mediating effects of telomere length variation on human health von Moix, Samuel, Sadler, Marie C, Kutalik, Zoltán, Auwerx, Chiara

Volltext

Mendelian randomization to assess causality between uromodulin, blood pressure and chronic kidney disease von Ponte, Belen, Sadler, Marie C., Olinger, Eric, Vollenweider, Peter, Bochud, Murielle, Padmanabhan, Sandosh, Hayward, Caroline, Kutalik, Zoltán, Devuyst, Olivier

Volltext

Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome von Porcu, Eleonora, Sadler, Marie C., Lepik, Kaido, Auwerx, Chiara, Wood, Andrew R., Weihs, Antoine, Sleiman, Maroun S. Bou, Ribeiro, Diogo M., Bandinelli, Stefania, Tanaka, Toshiko, Nauck, Matthias, Völker, Uwe, Delaneau, Olivier, Metspalu, Andres, Teumer, Alexander, Frayling, Timothy, Santoni, Federico A., Reymond, Alexandre, Kutalik, Zoltán

Volltext

The individual and global impact of copy-number variants on complex human traits von Auwerx, Chiara, Lepamets, Maarja, Sadler, Marie C., Patxot, Marion, Stojanov, Miloš, Baud, David, Mägi, Reedik, Esko, Tõnu, Metspalu, Andres, Milani, Lili, Mägi, Reedik, Nelis, Mari, Porcu, Eleonora, Reymond, Alexandre, Kutalik, Zoltán

Volltext

Exploiting the mediating role of the metabolome to unravel transcript-to-phenotype associations von Auwerx, Chiara, Sadler, Marie C, Woh, Tristan, Reymond, Alexandre, Kutalik, Zoltán, Porcu, Eleonora

Volltext

Sex- and age-dependent genetics of longevity in a heterogeneous mouse population von Bou Sleiman, Maroun, Roy, Suheeta, Gao, Arwen W, Sadler, Marie C, von Alvensleben, Giacomo V G, Li, Hao, Sen, Saunak, Harrison, David E, Nelson, James F, Strong, Randy, Miller, Richard A, Kutalik, Zoltán, Williams, Robert W, Auwerx, Johan

Volltext

Multi-layered genetic approaches to identify approved drug targets von Sadler, Marie C., Auwerx, Chiara, Deelen, Patrick, Kutalik, Zoltán

Volltext

The impact of 22q11.2 copy-number variants on human traits in the general population von Zamariolli, Malú, Auwerx, Chiara, Sadler, Marie C., van der Graaf, Adriaan, Lepik, Kaido, Schoeler, Tabea, Moysés-Oliveira, Mariana, Dantas, Anelisa G., Melaragno, Maria Isabel, Kutalik, Zoltán

Volltext

Response to Bassett et al von Zamariolli, Malú, Auwerx, Chiara, Sadler, Marie C, van der Graaf, Adriaan, Lepik, Kaido, Schoeler, Tabea, Moysés-Oliveira, Mariana, Dantas, Anelisa G, Melaragno, Maria Isabel, Kutalik, Zoltán

Volltext

Rare copy-number variants as modulators of common disease susceptibility von Auwerx, Chiara, Jõeloo, Maarja, Sadler, Marie C, Tesio, Nicolò, Ojavee, Sven, Clark, Charlie J, Mägi, Reedik, Reymond, Alexandre, Kutalik, Zoltán

Volltext

From pharmacogenetics to pharmaco-omics: Milestones and future directions von Auwerx, Chiara, Sadler, Marie C., Reymond, Alexandre, Kutalik, Zoltán

Volltext

Promises and challenges in pharmacoepigenetics von Smith, Delaney A, Sadler, Marie C, Altman, Russ B

Volltext

Causality-enriched epigenetic age uncouples damage and adaptation von Ying, Kejun, Liu, Hanna, Tarkhov, Andrei E, Sadler, Marie C, Lu, Ake T, Moqri, Mahdi, Horvath, Steve, Kutalik, Zoltán, Shen, Xia, Gladyshev, Vadim N

Volltext

Possible association of 16p11.2 copy number variation with altered lymphocyte and neutrophil counts von Giannuzzi, Giuliana, Chatron, Nicolas, Mannik, Katrin, Auwerx, Chiara, Pradervand, Sylvain, Willemin, Gilles, Hoekzema, Kendra, Nuttle, Xander, Chrast, Jacqueline, Sadler, Marie C., Porcu, Eleonora, Herault, Yann, Isidor, Bertrand, Gilbert-Dussardier, Brigitte, Eichler, Evan E., Kutalik, Zoltan, Reymond, Alexandre

Volltext

Identification of rare disease genes as drivers of common diseases through tissue-specific gene regulatory networks von Bakker, Olivier B., Claringbould, Annique, Westra, Harm-Jan, Wiersma, Henry, Boulogne, Floranne, Võsa, Urmo, Urzúa-Traslaviña, Carlos G., Mulcahy Symmons, Sophie, Zidan, Mahmoud M. M., Sadler, Marie C., Kutalik, Zoltán, Jonkers, Iris H., Franke, Lude, Deelen, Patrick

Volltext

Chromosomal deletions on 16p11.2 encompassing SH2B1 are associated with accelerated metabolic disease von Hanssen, Ruth, Auwerx, Chiara, Jõeloo, Maarja, Sadler, Marie C, Henning, Elana, Keogh, Julia, Bounds, Rebecca, Smith, Miriam, Firth, Helen V, Kutalik, Zoltán, Farooqi, I Sadaf, Reymond, Alexandre, Lawler, Katherine

Volltext

Lipid disturbances induced by psychotropic drugs: clinical and genetic predictors for early worsening of lipid levels and new-onset dyslipidaemia in Swiss psychiatric samples von Delacrétaz, Aurélie, Sadler, Marie, Gamma, Franziska, Preisig, Martin, Richard-Lepouriel, Hélène, von Gunten, Armin, Conus, Philippe, Plessen, Kerstin Jessica, Kutalik, Zoltan, Eap, Chin B.

Volltext

Author Correction: Possible association of 16p11.2 copy number variation with altered lymphocyte and neutrophil counts von Giannuzzi, Giuliana, Chatron, Nicolas, Mannik, Katrin, Auwerx, Chiara, Pradervand, Sylvain, Willemin, Gilles, Hoekzema, Kendra, Nuttle, Xander, Chrast, Jacqueline, Sadler, Marie C., Porcu, Eleonora, Herault, Yann, Isidor, Bertrand, Gilbert-Dussardier, Brigitte, Eichler, Evan E., Kutalik, Zoltan, Reymond, Alexandre

Volltext

Psychotropic-induced weight gain and telomere length: results from a one-year longitudinal study and a large population-based cohort von Piras, Marianna, Lin, Jue, Sadler, Marie Catherine, Ranjbar, Setareh, Grosu, Claire, Laaboub, Nermine, Preisig, Martin, Gamma, Franziska, Plessen, Kerstin Jessica, von Gunten, Armin, Conus, Philippe, Kutalik, Zoltan, Eap, Chin B.

Volltext