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    Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies von Kaptoge, Stephen, Butterworth, Adam S, Willeit, Peter, Bolton, Thomas, Paige, Ellie, Paul, Dirk S, Bell, Steven, Astle, William, Verschuren, W M Monique, Sato, Shinichi, Njølstad, Inger, Salomaa, Veikko, Yeap, Bu B, Melander, Olle, Marmot, Michael, Dahm, Christina C, Dale, Caroline E, van der Schouw, Yvonne T, Simons, Leon A, Schoufour, Josje D, Key, Timothy J, Moreno-Iribas, Conchi, Davidson, Karina W, Taylor, James O, Wallace, Robert B, Tumino, Rosario, Linneberg, Allan, Panico, Salvatore, Nietert, Paul J, Kromhout, Daan, Kiechl, Stefan, Palli, Domenico, Huerta, José M, Karakatsani, Anna, Kühn, Tilman, Grobbee, Diederick E, Kauhanen, Jussi, Wennberg, Maria, Cushman, Mary, Cooper, Jackie A, Rodriguez, Carlos J, Shaw, Jonathan E, Voortman, Trudy, Dallongeville, Jean, Brunner, Eric J, Lazo, Mariana, Leon, David A, Smith, George Davey, Peto, Richard, Jackson, Rod, Banks, Emily, Butterworth, Adam, Warnakula, Samantha, Paige, Ellie, Bell, Steven, Astle, William, Sato, Shinichi, Veikko, Salomaa, Flecther, Astrid, Melander, Olle, Kuller, Lewis H, Koenig, Wolfgang, Casiglia, Edoardo, Arndt, Volker, Völzke, Henry, Dahm, Christina C, Dale, Caroline E, Bergmann, Manuela, Crespo, Carlos, Kaaks, Rudolf, Simons, Leon A, Lagiou, Pagona, Key, Timothy J, Rodriguez, Beatriz, Moreno-Iribas, Conchi, Davidson, Karina W, Quiros, J. Ramon, Skeie, Guri, Salomaa, Veikko, Strandberg, Timo, Nietert, Paul J, Salamanca-Fernandez, Elena, Krumholz, Harlan M, Price, Jackie, Travis, Ruth C, Kühn, Tilman, Barrett-Connor, Elizabeth, van Schoor, Natasja, Boeing, Heiner, Overvad, Kim, Kauhanen, Jussi, Forouhi, Nita, Wennberg, Maria, Brenner, Hermann, Assmann, Gerd, Trevisan, Maurizio, Gillumn, Richard F, Thompson, Simon, Ferrari, Pietro, Davey Smith, George

    Veröffentlicht in The Lancet (British edition)

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    Long-term survival and cure fraction estimates for childhood cancer in Europe (EUROCARE-6): results from a population-based study von Botta, Laura, Capocaccia, Riccardo, Stiller, Charles, Cañete, Adela, Dal Maso, Luigino, Innos, Kaire, Erdmann, Friederike, Spix, Claudia, Lacour, Brigitte, Marcos-Gragera, Rafael, Murray, Deirdre, Hackl, Monika, Sekerija, Mario, Demetriou, Anna, Dušek, Ladislav, Krejci, Denisa, Storm, Hans, Mägi, Margit, Innos, Kaire, Pitkäniemi, Janne, Clavel, Jacqueline, Poulalhon, Claire, Lacour, Brigitte, Monnereau, Alain, Erdmann, Friederike, Spix, Claudia, Katalinic, Alexander, Petridou, Eleni, Markozannes, Georgios, Garami, Miklos, Walsh, Paul M, Mazzoleni, Guido, Vittadello, Fabio, Cuccaro, Francesco, Galasso, Rocco, Sampietro, Giuseppe, Gasparotto, Cinzia, Maifredi, Giovanni, Ferrante, Margherita, Torrisi, Antonina, Ballotari, Paola, Giacomazzi, Erica, Ferretti, Stefano, Baili, Paolo, Trama, Annalisa, Lillini, Roberto, Bernasconi, Alice, Bonfarnuzzo, Simone, Vener, Claudia, Del Monego, Giulia, Buratti, Lucia, Serraino, Diego, Taborelli, Martina, Capocaccia, Riccardo, Demuru, Elena, Di Benedetto, Corrado, Rossi, Silvia, Boni, Luca, Iacovacci, Silvia, Russo, Antonio Giampiero, Cavalieri d'Oro, Luca, Vitale, Maria Francesca, Vitale, Francesco, Chiranda, Giorgio, Sacerdote, Carlotta, Spata, Eugenia, Piras, Daniela, Dinaro, Ylenia, Castaing, Marine, Minerba, Sante, Candela, Giuseppina, Rizzello, Roberto Vito, Stracci, Fabrizio, Tagliabue, Giovanna, Rugge, Massimo, Pildava, Santa, Smailyte, Giedre, Azzopardi, Miriam, Ferreira, Ana Maria, Miranda, Ana, Safaei Diba, Chakameh, Zadnik, Vesna, Zagar, Tina, Franch Sureda, Paula, Lopez de Munain, Arantza, Aleman, Araceli, Vizcaino, Ana, Almela, Fernando, Sanchez, Maria Josè, Chirlaque, Maria Dolores, Guevara, Marcela, Ardanaz, Eva, Cañete-Nieto, Adela, Peris-Bonet, Rafael, Carulla, Maria, Visser, Otto, Stevens, Sarah, Gavin, Anna, Morrison, David, Huws, Dyfed Wyn

    Veröffentlicht in The lancet oncology

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    Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses von Sofianopoulou, Eleni, Kaptoge, Stephen K, Afzal, Shoaib, Jiang, Tao, Gill, Dipender, Gundersen, Thomas E, Bolton, Thomas R, Allara, Elias, Arnold, Matthew G, Mason, Amy M, Chung, Ryan, Pennells, Lisa A M, Shi, Fanchao, Sun, Luanluan, Willeit, Peter, Forouhi, Nita G, Langenberg, Claudia, Sharp, Stephen J, Panico, Salvatore, Engström, Gunnar, Melander, Olle, Tong, Tammy Y N, Perez-Cornago, Aurora, Norberg, Margareta, Johansson, Ingegerd, Katzke, Verena, Srour, Bernard, José Sánchez, María, Redondo-Sánchez, Daniel, Olsen, Anja, Dahm, Christina C, Overvad, Kim, Brustad, Magritt, Skeie, Guri, Moreno-Iribas, Conchi, Onland-Moret, N Charlotte, van der Schouw, Yvonne T, Tsilidis, Konstantinos K, Heath, Alicia K, Agnoli, Claudia, Krogh, Vittorio, de Boer, Ian H, Kobylecki, Camilla Jannie, Çolak, Yunus, Zittermann, Armin, Sundström, Johan, Welsh, Paul, Weiderpass, Elisabete, Aglago, Elom K, Ferrari, Pietro, Clarke, Robert, Boutron, Marie-Christine, Severi, Gianluca, MacDonald, Conor, Providencia, Rui, Masala, Giovanna, Zamora Ros, Raul, Boer, Jolanda, Verschuren, WM Monique, Cawthon, Peggy, Schierbeck, Louise L, Cooper, Cyrus, Schulze, Matthias B, Bergmann, Manuela M, Hannemann, Anke, Kiechl, Stefan, Brenner, Hermann, van Schoor, Natasja M, Albertorio, Juan R, Sacerdote, Carlotta, Linneberg, Allan, Kårhus, Line L, Huerta, José María, Imaz, Liher, Joergensen, Christel, Ben-Shlomo, Yoav, Lundqvist, Annamari, Gallacher, John, Sattar, Naveed, Wood, Angela M, Wareham, Nicholas J, Nordestgaard, Børge G, Di Angelantonio, Emanuele, Danesh, John, Butterworth, Adam S, Burgess, Stephen


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    Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche von Perry, John R. B., Ferreira, Teresa, Chasman, Daniel I., Esko, Tõnu, Thorleifsson, Gudmar, Albrecht, Eva, Ang, Wei Q., Corre, Tanguy, Cousminer, Diana L., Franceschini, Nora, Ganna, Andrea, Johnson, Andrew D., Kjellqvist, Sanela, Lunetta, Kathryn L., Porcu, Eleonora, Teumer, Alexander, Tikkanen, Emmi, Hottenga, Jouke-Jan, Pers, Tune H., Yerges-Armstrong, Laura M., Hua Zhao, Jing, Andrulis, Irene L., Anton-Culver, Hoda, Benitez, Javier, Blomqvist, Carl, Bolla, Manjeet K., Brenner, Hermann, Chang-Claude, Jenny, Chanock, Stephen, Chen, Jinhui, Chenevix-Trench, Georgia, Collée, J. Margriet, Davey Smith, George, Demerath, Ellen W., Dieffenbach, Aida K., Eriksson, Johan G., Flyger, Henrik, Franke, Lude, Gudbjartsson, Daniel F., Gudnason, Vilmundur, Guénel, Pascal, Guo, Suiqun, Hall, Per, Hartman, Catharina A., Heath, Andrew C., Hofman, Albert, Hooning, Maartje J., Hu, Frank B., Karasik, David, Kiel, Douglas P., Knight, Julia A., Kutalik, Zoltan, Lambrechts, Diether, Lindblom, Annika, Mägi, Reedik, Mannermaa, Arto, Martin, Nicholas G., Masson, Gisli, McArdle, Patrick F., Mihailov, Evelin, Nohr, Ellen A., Oostra, Ben A., Peacock, Munro, Peterlongo, Paolo, Peto, Julian, Postma, Dirkje S., Radice, Paolo, Rivadeneira, Fernando, Rose, Lynda M., Rudolph, Anja, Schlessinger, David, Sovio, Ulla, Tyrer, Jonathan, Vollenweider, Peter, Winqvist, Robert, Wolffenbuttel, Bruce H. R., Wright, Margaret J., Econs, Michael J., Loos, Ruth J. F., McCarthy, Mark I., Montgomery, Grant W., Rice, John P., Thorsteinsdottir, Unnur, van Duijn, Cornelia M., Alizadeh, Behrooz Z., Bergmann, Sven, Boerwinkle, Eric, Crisponi, Laura, Gasparini, Paolo, Gieger, Christian, Järvelin, Marjo-Riitta, Kraft, Peter, Ridker, Paul M., Snieder, Harold, Sørensen, Thorkild I. A., Spector, Tim D., Uitterlinden, André G., Zygmunt, Marek, Murray, Anna, Ong, Ken K.

    Veröffentlicht in Nature (London)

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    Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility von Wessel, Jennifer, Chu, Audrey Y, Willems, Sara M, Dauriz, Marco, Raghavan, Sridharan, Hidalgo, Bertha, An, Ping, Lu, Yingchang, Ehm, Margaret G, Baldridge, Abigail S, Freitag, Daniel F, Garcia, Melissa E, Hara, Kazuo, Jakobsdottir, Johanna, Lange, Leslie A, Layton, Jill C, Li, Man, Morrison, Alanna C, Peters, Marjolein J, Southam, Lorraine, Stoiber, Marcus H, Strawbridge, Rona J, Varga, Tibor V, Barbieri, Caterina, Bombieri, Cristina, Bowden, Donald W, Burns, Sean M, Chen, Yuning, Chen, Yii-DerI, Cheng, Ching-Yu, Ehret, Georg B, Eiriksdottir, Gudny, Escher, Stefan A, Frånberg, Mattias, Gambaro, Giovanni, Goel, Anuj, Grove, Megan L, Karaleftheri, Maria, Kirkpatrick, Andrea, Kraja, Aldi T, Kuusisto, Johanna, Lange, Ethan M, Lee, I T, Lee, Wen-Jane, Leong, Aaron, Liao, Jiemin, Lindgren, Cecilia M, Malerba, Giovanni, Mamakou, Vasiliki, Maruthur, Nisa M, McLeod, Olga, Mohlke, Karen L, Muzny, Donna M, Renström, Frida, Rice, Ken, Sala, Cinzia F, Soranzo, Nicole, Speliotes, Elizabeth K, Stirrups, Kathleen, Thanopoulou, Anastasia, Traglia, Michela, Tsafantakis, Emmanouil, Javad, Sundas, Yanek, Lisa R, Becker, Diane M, Bis, Joshua C, Brown, James B, Ingelsson, Erik, Karter, Andrew J, Lorenzo, Carlos, Peloso, Gina M, Vaidya, Dhananjay, Varma, Rohit, Wagenknecht, Lynne E, Dedoussis, George, Deloukas, Panos, Franco, Oscar H, Gibbs, Richard A, Gudnason, Vilmundur, Hofman, Albert, Jansson, Jan-Håkan, Langenberg, Claudia, Launer, Lenore J, Levy, Daniel, Oostra, Ben A, Padmanabhan, Sandosh, Pankow, James S, Rudan, Igor, Schulze, Matthias B, Smith, Blair H, Walker, Mark, Wong, Tien Y, Laakso, Markku, Borecki, Ingrid B, van Duijn, Cornelia M, Waterworth, Dawn M, Loos, Ruth J.F., Meigs, James B, Scott, Robert A, Goodarzi, Mark O

    Veröffentlicht in Nature communications

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    Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses von Sofianopoulou, Eleni, Kaptoge, Stephen K, Afzal, Shoaib, Jiang, Tao, Gill, Dipender, Gundersen, Thomas E, Bolton, Thomas R, Allara, Elias, Arnold, Matthew G, Mason, Amy M, Chung, Ryan, Pennells, Lisa A M, Shi, Fanchao, Sun, Luanluan, Willeit, Peter, Forouhi, Nita G, Langenberg, Claudia, Sharp, Stephen J, Panico, Salvatore, Engström, Gunnar, Melander, Olle, Tong, Tammy Y N, Perez-Cornago, Aurora, Norberg, Margareta, Johansson, Ingegerd, Katzke, Verena, Srour, Bernard, Sánchez, María José, Redondo-Sánchez, Daniel, Olsen, Anja, Dahm, Christina C, Overvad, Kim, Brustad, Magritt, Skeie, Guri, Moreno-Iribas, Conchi, Onland-Moret, N Charlotte, van der Schouw, Yvonne T, Tsilidis, Konstantinos K, Heath, Alicia K, Agnoli, Claudia, Krogh, Vittorio, de Boer, Ian H, Kobylecki, Camilla Jannie, Çolak, Yunus, Zittermann, Armin, Sundström, Johan, Welsh, Paul, Weiderpass, Elisabete, Aglago, Elom K, Ferrari, Pietro, Clarke, Robert, Boutron, Marie-Christine, Severi, Gianluca, MacDonald, Conor, Providencia, Rui, Masala, Giovanna, Zamora Ros, Raul, Boer, Jolanda, Verschuren, Wm Monique, Cawthon, Peggy, Schierbeck, Louise L, Cooper, Cyrus, Schulze, Matthias B, Bergmann, Manuela M, Hannemann, Anke, Kiechl, Stefan, Brenner, Hermann, van Schoor, Natasja M, Albertorio, Juan R, Sacerdote, Carlotta, Linneberg, Allan, Kårhus, LineL, Huerta, José María, Imaz, Liher, Joergensen, Christel, Ben-Shlomo, Yoav, Lundqvist, Annamari, Gallacher, John, Sattar, Naveed, Wood, Angela M, Wareham, Nicholas J, Nordestgaard, Børge G, Di Angelantonio, Emanuele, Danesh, John, Butterworth, Adam S, Burgess, Stephen


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    Blood Pressure Loci Identified with a Gene-Centric Array von Johnson, Toby, Gaunt, Tom R., Newhouse, Stephen J., Padmanabhan, Sandosh, Tomaszewski, Maciej, Kumari, Meena, Morris, Richard W., Tzoulaki, Ioanna, O'Brien, Eoin T., Poulter, Neil R., Sever, Peter, Shields, Denis C., Thom, Simon, Whincup, Peter H., Brown, Morris J., Connell, John M., Dobson, Richard J., Howard, Philip J., Mein, Charles A., Onipinla, Abiodun, Shaw-Hawkins, Sue, Zhang, Yun, Smith, George Davey, Day, Ian N.M., Lawlor, Debbie A., Goodall, Alison H., Fowkes, F. Gerald, Abecasis, Gonçalo R., Elliott, Paul, Gateva, Vesela, Braund, Peter S., Burton, Paul R., Nelson, Christopher P., Tobin, Martin D., van der Harst, Pim, Neuvrith, Hani, Salvi, Erika, Staessen, Jan A., Stucchi, Andrea, Devos, Nabila, Jeunemaitre, Xavier, Plouin, Pierre-François, Tichet, Jean, Juhanson, Peeter, Org, Elin, Putku, Margus, Sõber, Siim, Veldre, Gudrun, Viigimaa, Margus, Levinsson, Anna, Rosengren, Annika, Thelle, Dag S., Hastie, Claire E., Hedner, Thomas, Lee, Wai K., Melander, Olle, Wahlstrand, Björn, Hardy, Rebecca, Wong, Andrew, Cooper, Jackie A., Palmen, Jutta, Chen, Li, Stewart, Alexandre F.R., Wells, George A., Westra, Harm-Jan, Wolfs, Marcel G.M., Clarke, Robert, Franzosi, Maria Grazia, Goel, Anuj, Hamsten, Anders, Lathrop, Mark, Peden, John F., Seedorf, Udo, Watkins, Hugh, Sambrook, Jennifer, Stephens, Jonathan, Casas, Juan-Pablo, Drenos, Fotios, Holmes, Michael V., Kivimaki, Mika, Shah, Sonia, Shah, Tina, Talmud, Philippa J., Whittaker, John, Wallace, Chris, Delles, Christian, Laan, Maris, Kuh, Diana, Humphries, Steve E., Nyberg, Fredrik, Cusi, Daniele, Roberts, Robert, Newton-Cheh, Christopher, Franke, Lude, Stanton, Alice V., Dominiczak, Anna F., Hingorani, Aroon D., Samani, Nilesh J., Caulfield, Mark J., Munroe, Patricia B.


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    Effects of Long-Term Averaging of Quantitative Blood Pressure Traits on the Detection of Genetic Associations von Guo, Xiuqing, Bis, Joshua C., Yang, Min-Lee, Ehret, Georg, Sijbrands, Eric J., Eiriksdottir, Gudny, Pihur, Vasyl, Vasan, Ramachandran S., Gateva, Vesela, Tobin, Martin D., Bochud, Murielle, Zhao, Jing Hua, Heath, Simon C., Eyheramendy, Susana, Zhang, Feng, Farrall, Martin, Wallace, Chris, Khaw, Kay-Tee, Nilsson, Peter, Polidoro, Silvia, Grobbee, Diederick E., Onland-Moret, N. Charlotte, Teumer, Alexander, Luan, Jian’an, Burton, Paul R., McArdle, Wendy L., Brown, Morris, Newhouse, Stephen J., Webster, John, Zeggini, Eleftheria, Bergmann, Sven, Song, Kijoung, Waeber, Gerard, Yuan, Xin, Groop, Leif, Di Gregorio, Alessandra, Guarrera, Simonetta, Panico, Salvatore, Romanazzi, Valeria, Vineis, Paolo, Luben, Robert N., Crawford, Gabriel J., Boehnke, Michael, Collins, Francis S., Jackson, Anne U., Stringham, Heather M., Morken, Mario A., Gieger, Christian, Wichmann, H. Erich, O’Donnell, Christopher J., Siscovick, David S., O’Reilly, Paul F., Peltonen, Leena, Pouta, Anneli, van Gilst, Wiek H., Clarke, Robert, Goel, Anuj, Syvänen, Ann-Christine, Scheet, Paul, Scuteri, Angelo, Ernst, Florian, Felix, Stephan B., Lorbeer, Roberto, Völker, Uwe, Hercberg, Serge, Zeleneka, Diana, Deloukas, Panos, Soranzo, Nicole, Zhai, Guangju, Laakso, Markku, Forouhi, Nita G., Völzke, Henry, Numans, Mattijs E., Navis, Gerjan, Paterson, Andrew D., Bandinelli, Stefania, Spector, Tim D., Altshuler, David, Strachan, David P., Jarvelin, Marjo-Riitta, Melander, Olle, Loos, Ruth J.F., Caulfield, Mark, Raffel, Leslie J., Amin, Najaf, Rotter, Jerome I., Launer, Lenore J., Caulfield, Mark, Morrison, Alanna C., Li, Guo, Harris, Tamara B., Zhang, He, Siscovick, David S., Gao, Wei, Rivadeneira, Fernando, Willer, Cristen J., Huo, Yong, Palmas, Walter, van Duijn, Cornelia, Fornage, Myriam


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    Rare coding variants and X-linked loci associated with age at menarche von Lunetta, Kathryn L., Day, Felix R., Sulem, Patrick, Ruth, Katherine S., Tung, Joyce Y., Hinds, David A., Esko, Tõnu, Elks, Cathy E., Altmaier, Elisabeth, He, Chunyan, Huffman, Jennifer E., Mihailov, Evelin, Porcu, Eleonora, Robino, Antonietta, Rose, Lynda M., Schick, Ursula M., Stolk, Lisette, Teumer, Alexander, Thompson, Deborah J., Traglia, Michela, Wang, Carol A., Yerges-Armstrong, Laura M., Antoniou, Antonis C., Barbieri, Caterina, Coviello, Andrea D., Cucca, Francesco, Demerath, Ellen W., Dunning, Alison M., Gandin, Ilaria, Grove, Megan L., Gudbjartsson, Daniel F., Hocking, Lynne J., Hofman, Albert, Huang, Jinyan, Jackson, Rebecca D., Karasik, David, Kriebel, Jennifer, Lange, Ethan M., Lange, Leslie A., Langenberg, Claudia, Li, Xin, Luan, Jian'an, Mägi, Reedik, Morrison, Alanna C., Padmanabhan, Sandosh, Pirie, Ailith, Polasek, Ozren, Porteous, David, Reiner, Alex P., Rivadeneira, Fernando, Rudan, Igor, Sala, Cinzia F., Schlessinger, David, Scott, Robert A., Stöckl, Doris, Visser, Jenny A., Völker, Uwe, Vozzi, Diego, Wilson, James G., Zygmunt, Marek, Boerwinkle, Eric, Buring, Julie E., Crisponi, Laura, Easton, Douglas F., Hayward, Caroline, Hu, Frank B., Liu, Simin, Metspalu, Andres, Pennell, Craig E., Ridker, Paul M., Strauch, Konstantin, Streeten, Elizabeth A., Toniolo, Daniela, Uitterlinden, André G., Ulivi, Sheila, Völzke, Henry, Wareham, Nicholas J., Wellons, Melissa, Franceschini, Nora, Chasman, Daniel I., Thorsteinsdottir, Unnur, Murray, Anna, Stefansson, Kari, Murabito, Joanne M., Ong, Ken K., Perry, John R. B.

    Veröffentlicht in Nature communications

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