Sphingosine‐1‐phosphate antibodies as potential agents in the treatment of cancer and age‐related macular degeneration von Sabbadini, Roger A.

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Autophagy in Oncogenic K-Ras Promotes Basal Extrusion of Epithelial Cells by Degrading S1P von Slattum, Gloria, Gu, Yapeng, Sabbadini, Roger, Rosenblatt, Jody

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Epithelial cell extrusion requires the sphingosine-1-phosphate receptor 2 pathway von Gu, Yapeng, Forostyan, Tetyana, Sabbadini, Roger, Rosenblatt, Jody

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Anti-S1P Antibody as a Novel Therapeutic Strategy for VEGFR TKI-Resistant Renal Cancer von Zhang, Liang, Wang, Xiaoen, Bullock, Andrea J, Callea, Marcella, Shah, Harleen, Song, Jiaxi, Moreno, Kelli, Visentin, Barbara, Deutschman, Douglas, Alsop, David C, Atkins, Michael B, Mier, James W, Signoretti, Sabina, Bhasin, Manoj, Sabbadini, Roger A, Bhatt, Rupal S

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Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer von Ader, Isabelle, Gstalder, Cécile, Bouquerel, Pierre, Golzio, Muriel, Andrieu, Guillaume, Zalvidea, Santiago, Richard, Sylvain, Sabbadini, Roger A, Malavaud, Bernard, Cuvillier, Olivier

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Anti-lysophosphatidic acid antibodies improve traumatic brain injury outcomes von Crack, Peter J, Zhang, Moses, Morganti-Kossmann, Maria Cristina, Morris, Andrew J, Wojciak, Jonathan M, Fleming, Jonathan K, Karve, Ila, Wright, David, Sashindranath, Maithili, Goldshmit, Yona, Conquest, Alison, Daglas, Maria, Johnston, Leigh A, Medcalf, Robert L, Sabbadini, Roger A, Pébay, Alice

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Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages von Visentin, Barbara, Vekich, John A., Sibbald, Bradley J., Cavalli, Amy L., Moreno, Kelli M., Matteo, Rosalia G., Garland, William A., Lu, Yiling, Yu, Shuangxing, Hall, Hassan S., Kundra, Vikas, Mills, Gordon B., Sabbadini, Roger A.

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Sphingosine 1-phosphate signaling through its receptor S1P5 promotes chromosome segregation and mitotic progression von Andrieu, Guillaume, Ledoux, Adeline, Branka, Sophie, Bocquet, Magalie, Gilhodes, Julia, Walzer, Thierry, Kasahara, Kousuke, Inagaki, Masaki, Sabbadini, Roger A., Cuvillier, Olivier, Hatzoglou, Anastassia

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Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor-β-stimulated collagen production by cardiac fibroblasts von Gellings Lowe, Nicole, Swaney, James S., Moreno, Kelli M., Sabbadini, Roger A.

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Intracellular S1P generation is essential for S1P-induced motility of human lung endothelial cells: role of sphingosine kinase 1 and S1P lyase von Berdyshev, Evgeny V, Gorshkova, Irina, Usatyuk, Peter, Kalari, Satish, Zhao, Yutong, Pyne, Nigel J, Pyne, Susan, Sabbadini, Roger A, Garcia, Joe G N, Natarajan, Viswanathan

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Blockage of Lysophosphatidic Acid Signaling Improves Spinal Cord Injury Outcomes von Goldshmit, Yona, Matteo, Rosalia, Sztal, Tamar, Ellett, Felix, Frisca, Frisca, Moreno, Kelli, Crombie, Duncan, Lieschke, Graham J, Currie, Peter D, Sabbadini, Roger A, Pébay, Alice

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Nervous system delivery of antilysophosphatidic acid antibody by nasal application attenuates mechanical allodynia after traumatic brain injury in rats von Eisenried, Andreas, Meidahl, Anders C.N., Klukinov, Michael, Tzabazis, Alexander Z., Sabbadini, Roger A., Clark, J. David, Yeomans, David C.

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Sphingosine 1-phosphate mediates hyperalgesia via a neutrophil-dependent mechanism von Finley, Amanda, Chen, Zhoumou, Esposito, Emanuela, Cuzzocrea, Salvatore, Sabbadini, Roger, Salvemini, Daniela

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Matrix-Assisted Laser Desorption Ionization Mapping of Lysophosphatidic Acid Changes after Traumatic Brain Injury and the Relationship to Cellular Pathology von McDonald, Whitney S., Jones, Elizabeth E., Wojciak, Jonathan M., Drake, Richard R., Sabbadini, Roger A., Harris, Neil G.

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Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells von Brizuela, Leyre, Martin, Claire, Jeannot, Pauline, Ader, Isabelle, Gstalder, Cécile, Andrieu, Guillaume, Bocquet, Magalie, Laffosse, Jean-Michel, Gomez-Brouchet, Anne, Malavaud, Bernard, Sabbadini, Roger A., Cuvillier, Olivier

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Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1‐phosphate signalling to regulate tumour metastasis von Ponnusamy, Suriyan, Selvam, Shanmugam Panneer, Mehrotra, Shikhar, Kawamori, Toshihiko, Snider, Ashley J., Obeid, Lina M., Shao, Yuan, Sabbadini, Roger, Ogretmen, Besim

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Making a Difference: “Serendipity favors the prepared mind.” - Louis Pasteur von Sabbadini, Roger

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Making a Difference von Roger Sabbadini

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The sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 axis regulates early airway T-cell infiltration in murine mast cell–dependent acute allergic responses von Oskeritzian, Carole A., PhD, Hait, Nitai C., PhD, Wedman, Piper, BS, Chumanevich, Alena, MS, Kolawole, Elizabeth M., PhD, Price, Megan M., PhD, Falanga, Yves T., PhD, Harikumar, Kuzhuvelil B., PhD, Ryan, John J., PhD, Milstien, Sheldon, PhD, Sabbadini, Roger, PhD, Spiegel, Sarah, PhD

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Acid ceramidase confers radioresistance to glioblastoma cells von Doan, Ninh B, Nguyen, Ha S, Al-Gizawiy, Mona M, Mueller, Wade M, Sabbadini, Roger A, Rand, Scott D, Connelly, Jennifer M, Chitambar, Christopher R, Schmainda, Kathleen M, Mirza, Shama P

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