Human papillomavirus and the landscape of secondary genetic alterations in oral cancers von Gillison, Maura L, Akagi, Keiko, Xiao, Weihong, Jiang, Bo, Pickard, Robert K L, Li, Jingfeng, Swanson, Benjamin J, Agrawal, Amit D, Zucker, Mark, Stache-Crain, Birgit, Emde, Anne-Katrin, Geiger, Heather M, Robine, Nicolas, Coombes, Kevin R, Symer, David E

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Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability von Akagi, Keiko, Li, Jingfeng, Broutian, Tatevik R, Padilla-Nash, Hesed, Xiao, Weihong, Jiang, Bo, Rocco, James W, Teknos, Theodoros N, Kumar, Bhavna, Wangsa, Danny, He, Dandan, Ried, Thomas, Symer, David E, Gillison, Maura L

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HPV integration hijacks and multimerizes a cellular enhancer to generate a viral-cellular super-enhancer that drives high viral oncogene expression von Warburton, Alix, Redmond, Catherine J, Dooley, Katharine E, Fu, Haiqing, Gillison, Maura L, Akagi, Keiko, Symer, David E, Aladjem, Mirit I, McBride, Alison A

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In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice von El Refaey, Mona, Xu, Li, Gao, Yandi, Canan, Benjamin D, Adesanya, T.M Ayodele, Warner, Sarah C, Akagi, Keiko, Symer, David E, Mohler, Peter J, Ma, Jianjie, Janssen, Paul M.L, Han, Renzhi

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A germline mutation in SRRM2, a splicing factor gene, is implicated in papillary thyroid carcinoma predisposition von Tomsic, Jerneja, He, Huiling, Akagi, Keiko, Liyanarachchi, Sandya, Pan, Qun, Bertani, Blake, Nagy, Rebecca, Symer, David E., Blencowe, Benjamin J., Chapelle, Albert de la

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The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection von Schliehe, Christopher, Flynn, Elizabeth K, Vilagos, Bojan, Richson, Udochuku, Swaminathan, Savitha, Bosnjak, Berislav, Bauer, Lisa, Kandasamy, Richard K, Griesshammer, Isabel M, Kosack, Lindsay, Schmitz, Frank, Litvak, Vladimir, Sissons, James, Lercher, Alexander, Bhattacharya, Anannya, Khamina, Kseniya, Trivett, Anna L, Tessarollo, Lino, Mesteri, Ildiko, Hladik, Anastasiya, Merkler, Doron, Kubicek, Stefan, Knapp, Sylvia, Epstein, Michelle M, Symer, David E, Aderem, Alan, Bergthaler, Andreas

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Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer von He, Huiling, Li, Wei, Liyanarachchi, Sandya, Srinivas, Mukund, Wang, Yanqiang, Akagi, Keiko, Wang, Yao, Wu, Dayong, Wang, Qianben, Jin, Victor, Symer, David E., Shen, Rulong, Phay, John, Nagy, Rebecca, de la Chapelle, Albert

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Mutations in U4atac snRNA, a Component of the Minor Spliceosome, in the Developmental Disorder MOPD I von He, Huiling, Liyanarachchi, Sandya, Akagi, Keiko, Nagy, Rebecca, Li, Jingfeng, Dietrich, Rosemary C., Li, Wei, Sebastian, Nikhil, Wen, Bernard, Xin, Baozhong, Singh, Jarnail, Yan, Pearlly, Alder, Hansjuerg, Haan, Eric, Wieczorek, Dagmar, Albrecht, Beate, Puffenberger, Erik, Wang, Heng, Westman, Judith A., Padgett, Richard A., Symer, David E., de la Chapelle, Albert

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Merkel Cell Polyomavirus Exhibits Dominant Control of the Tumor Genome and Transcriptome in Virus-Associated Merkel Cell Carcinoma von Starrett, Gabriel J, Marcelus, Christina, Cantalupo, Paul G, Katz, Joshua P, Cheng, Jingwei, Akagi, Keiko, Thakuria, Manisha, Rabinowits, Guilherme, Wang, Linda C, Symer, David E, Pipas, James M, Harris, Reuben S, DeCaprio, James A

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An antisense promoter in mouse L1 retrotransposon open reading frame-1 initiates expression of diverse fusion transcripts and limits retrotransposition von Li, Jingfeng, Kannan, Manoj, Trivett, Anna L, Liao, Hongling, Wu, Xiaolin, Akagi, Keiko, Symer, David E

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Characterization of a new chronic lymphocytic leukemia cell line for mechanistic in vitro and in vivo studies relevant to disease von Hertlein, Erin, Beckwith, Kyle A, Lozanski, Gerard, Chen, Timothy L, Towns, William H, Johnson, Amy J, Lehman, Amy, Ruppert, Amy S, Bolon, Brad, Andritsos, Leslie, Lozanski, Arletta, Rassenti, Laura, Zhao, Weiqiang, Jarvinen, Tiina M, Senter, Leigha, Croce, Carlo M, Symer, David E, de la Chapelle, Albert, Heerema, Nyla A, Byrd, John C

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Ultra-rare mutation in long-range enhancer predisposes to thyroid carcinoma with high penetrance von He, Huiling, Li, Wei, Wu, Dayong, Nagy, Rebecca, Liyanarachchi, Sandya, Akagi, Keiko, Jendrzejewski, Jaroslaw, Jiao, Hong, Hoag, Kevin, Wen, Bernard, Srinivas, Mukund, Waidyaratne, Gavisha, Wang, Rui, Wojcicka, Anna, Lattimer, Ilene R, Stachlewska, Elzbieta, Czetwertynska, Malgorzata, Dlugosinska, Joanna, Gierlikowski, Wojciech, Ploski, Rafal, Krawczyk, Marek, Jazdzewski, Krystian, Kere, Juha, Symer, David E, Jin, Victor, Wang, Qianben, de la Chapelle, Albert

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Mouse endogenous retroviruses can trigger premature transcriptional termination at a distance von Li, Jingfeng, Akagi, Keiko, Hu, Yongjun, Trivett, Anna L, Hlynialuk, Christopher J W, Swing, Deborah A, Volfovsky, Natalia, Morgan, Tamara C, Golubeva, Yelena, Stephens, Robert M, Smith, David E, Symer, David E

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Targeted single-cell proteomic analysis identifies new liquid biopsy biomarkers associated with multiple myeloma von Setayesh, Sonia M., Ndacayisaba, Libere J., Rappard, Kate E., Hennes, Valerie, Rueda, Luz Yurany Moreno, Tang, Guilin, Lin, Pei, Orlowski, Robert Z., Symer, David E., Manasanch, Elisabet E., Shishido, Stephanie N., Kuhn, Peter

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Oral Human Papillomavirus Infection Before and After Treatment for Human Papillomavirus 16–Positive and Human Papillomavirus 16–Negative Head and Neck Squamous Cell Carcinoma von AGRAWAL, Yuri, KOCH, Wayne M, WEIHONG XIAO, WESTRA, William H, TRIVETT, Anna L, SYMER, David E, GILLISON, Maura L

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Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR von Van Duyne, Rachel, Easley, Rebecca, Wu, Weilin, Berro, Reem, Pedati, Caitlin, Klase, Zachary, Kehn-Hall, Kylene, Flynn, Elizabeth K, Symer, David E, Kashanchi, Fatah

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The bonobo genome compared with the chimpanzee and human genomes von Prüfer, Kay, Munch, Kasper, Hellmann, Ines, Akagi, Keiko, Miller, Jason R., Walenz, Brian, Koren, Sergey, Sutton, Granger, Kodira, Chinnappa, Winer, Roger, Knight, James R., Mullikin, James C., Meader, Stephen J., Ponting, Chris P., Lunter, Gerton, Higashino, Saneyuki, Hobolth, Asger, Dutheil, Julien, Karakoç, Emre, Alkan, Can, Sajjadian, Saba, Catacchio, Claudia Rita, Ventura, Mario, Marques-Bonet, Tomas, Eichler, Evan E., André, Claudine, Atencia, Rebeca, Mugisha, Lawrence, Junhold, Jörg, Patterson, Nick, Siebauer, Michael, Good, Jeffrey M., Fischer, Anne, Ptak, Susan E., Lachmann, Michael, Symer, David E., Mailund, Thomas, Schierup, Mikkel H., Andrés, Aida M., Kelso, Janet, Pääbo, Svante

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Intratumoral Heterogeneity and Clonal Evolution Induced by HPV Integration von Akagi, Keiko, Symer, David E, Mahmoud, Medhat, Jiang, Bo, Goodwin, Sara, Wangsa, Darawalee, Li, Zhengke, Xiao, Weihong, Dunn, Joe Dan, Ried, Thomas, Coombes, Kevin R, Sedlazeck, Fritz J, Gillison, Maura L

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Diverse tumorigenic consequences of human papillomavirus integration in primary oropharyngeal cancers von Symer, David E, Akagi, Keiko, Geiger, Heather M, Song, Yang, Li, Gaiyun, Emde, Anne-Katrin, Xiao, Weihong, Jiang, Bo, Corvelo, André, Toussaint, Nora C, Li, Jingfeng, Agrawal, Amit, Ozer, Enver, El-Naggar, Adel K, Du, Zoe, Shewale, Jitesh B, Stache-Crain, Birgit, Zucker, Mark, Robine, Nicolas, Coombes, Kevin R, Gillison, Maura L

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Identification of Rare Variants Predisposing to Thyroid Cancer von Wang, Yanqiang, Liyanarachchi, Sandya, Miller, Katherine E., Nieminen, Taina T., Comiskey, Daniel F., Li, Wei, Brock, Pamela, Symer, David E., Akagi, Keiko, DeLap, Katherine E., He, Huiling, Koboldt, Daniel C., de la Chapelle, Albert

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