Small molecule splicing modifiers with systemic HTT-lowering activity von Bhattacharyya, Anuradha, Trotta, Christopher R., Narasimhan, Jana, Wiedinger, Kari J., Li, Wencheng, Effenberger, Kerstin A., Woll, Matthew G., Jani, Minakshi B., Risher, Nicole, Yeh, Shirley, Cheng, Yaofeng, Sydorenko, Nadiya, Moon, Young-Choon, Karp, Gary M., Weetall, Marla, Dakka, Amal, Gabbeta, Vijayalakshmi, Naryshkin, Nikolai A., Graci, Jason D., Tripodi, Thomas, Southwell, Amber, Hayden, Michael, Colacino, Joseph M., Peltz, Stuart W.

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Self-renewal as a therapeutic target in human colorectal cancer von Kreso, Antonija, van Galen, Peter, Pedley, Nicholas M, Lima-Fernandes, Evelyne, Frelin, Catherine, Davis, Thomas, Cao, Liangxian, Baiazitov, Ramil, Du, Wu, Sydorenko, Nadiya, Moon, Young-Choon, Gibson, Lianne, Wang, Yadong, Leung, Cherry, Iscove, Norman N, Arrowsmith, Cheryl H, Szentgyorgyi, Eva, Gallinger, Steven, Dick, John E, O'Brien, Catherine A

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Evaluating the Mechanism and Therapeutic Potential of PTC-028, a Novel Inhibitor of BMI-1 Function in Ovarian Cancer von Dey, Anindya, Xiong, Xunhao, Crim, Aleia, Dwivedi, Shailendra Kumar Dhar, Mustafi, Soumyajit Banerjee, Mukherjee, Priyabrata, Cao, Liangxian, Sydorenko, Nadiya, Baiazitov, Ramil, Moon, Young-Choon, Dumble, Melissa, Davis, Thomas, Bhattacharya, Resham

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A Formal [3 + 3] Cycloaddition Approach to Natural-Product Synthesis von Hsung, Richard P., Kurdyumov, Aleksey V., Sydorenko, Nadiya

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A Formal [3 + 3] Cycloaddition Reaction. 5. An Enantioselective Intramolecular Formal Aza-[3 + 3] Cycloaddition Reaction Promoted by Chiral Amine Salts von Gerasyuto, Aleksey I, Hsung, Richard P, Sydorenko, Nadiya, Slafer, Brian

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Abstract 5517: PTC596-induced Bmi1 hyper-phosphorylation via Cdk1/2 activation resulting in tumor stem cell depletion von Kim, Min Jung, Cao, Liangxian, Sheedy, Josephine, Risher, Nicole, Dumble, Melissa, Lee, Chang-Sun, Sydorenko, Nadiya, Baiazitov, Ramil, Du, Wu, Moon, Young-Choon, Weetall, Marla L., Colacino, Joseph, Davis, Thomas W.

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Unexpected Observation of the Dimroth Rearrangement in the Ribosylation of 4‑Aminopyrimidines von Baiazitov, Ramil Y, Sydorenko, Nadiya, Ren, Hongyu, Moon, Young-Choon

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BMI-1 Targeting Interferes with Patient-Derived Tumor-Initiating Cell Survival and Tumor Growth in Prostate Cancer von Bansal, Nitu, Bartucci, Monica, Yusuff, Shamila, Davis, Stephani, Flaherty, Kathleen, Huselid, Eric, Patrizii, Michele, Jones, Daniel, Cao, Liangxian, Sydorenko, Nadiya, Moon, Young-Choon, Zhong, Hua, Medina, Daniel J, Kerrigan, John, Stein, Mark N, Kim, Isaac Y, Davis, Thomas W, DiPaola, Robert S, Bertino, Joseph R, Sabaawy, Hatem E

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Discovery and SAR Studies of Potent Modulators of BMI‐1 Expression von Baiazitov, Ramil Y., Sydorenko, Nadiya, Du, Wu, Ren, Hongyu, Cao, Liang, Davis, Thomas, Cintron‐Lue, Katherine, Kim, Min‐Jung, Zhuo, Jin, Mody, Shreshtha, Weetall, Marla, Sheedy, Josephine, Risher, Nicole, Almstead, Neil, Moon, Young‐Choon

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Torquoselective 6π-Electron Electrocyclic Ring Closure of 1-Azatrienes Containing Acyclic Chirality at the C-Terminus von Sydorenko, Nadiya, Hsung, Richard P, Vera, Eymi L

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Abstract 2529: Optimization of small molecules targeting BMI1 protein expression. Part 1. Amino-thiazoles: the first-in-class highly potent inhibitors of BMI1 protein von Sydorenko, Nadiya, Baiazitov, Ramil, Choi, Soongyu, Lee, Chang-Sun, Cao, Liangxian, Davis, Thomas W., Almstead, Neil G., Moon, Young-Choon

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Abstract 2528: Optimization of small molecules targeting BMI1 protein expression. Part 2. Improved potency, oral bioavailability, and in vivo efficacy of amino-pyrazines and amino-... von Baiazitov, Ramil, Sydorenko, Nadiya, Ren, Hongyu, Du, Wu, Paget, Steve, Wilde, Richard, Liu, Ronggang, Lee, Chang-Sun, Cao, Liangxian, Davis, Thomas W., Almstead, Neil G., Moon, Young-Choon

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A Lewis Acid-Catalyzed Formal [3 + 3] Cycloaddition of α,β-Unsaturated Aldehydes with 4-Hydroxy-2-Pyrone, Diketones, and Vinylogous Esters von Kurdyumov, Aleksey V, Lin, Nan, Hsung, Richard P, Gullickson, Glen C, Cole, Kevin P, Sydorenko, Nadiya, Swidorski, Jacob J

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Tetronamides as Latent Acyclic Vinylogous Amides in Formal Aza-[3 + 3] Cycloaddition Reactions with α,β-Unsaturated Iminium Salts. An Unexpected Rearrangement and an Approach to Sy... von Sydorenko, Nadiya, Hsung, Richard P, Darwish, Ossama Saleh, Hahn, Juliet M, Liu, Jia

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Total syntheses of enantiomerically enriched R-(+)- and S-(-)-deplancheine von Sydorenko, Nadiya, Zificsak, Craig A, Gerasyuto, Aleksey I, Hsung, Richard P

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Torquoselective 6pi-electron electrocyclic ring closure of 1-azatrienes containing acyclic chirality at the C-terminus von Sydorenko, Nadiya, Hsung, Richard P, Vera, Eymi L

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METHODS FOR TREATING HUNTINGTON'S DISEASE von JANI, Minakshi B, SYDORENKO, Nadiya, BHATTACHARYYA, Anuradha, WOLL, Matthew G

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Compounds for treating huntington's disease von Sydorenko, Nadiya, Moon, Young-Choon, Babu, Suresh, Narasimhan, Jana, Patel, Jigar S, Bhattacharyya, Anuradha

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COMPOUNDS AND METHODS FOR TREATING HUNTINGTON'S DISEASE von JANI, MINAKSHI, BABU, SURESH, BHATTACHARYYA, ANURADHA, HWANG, SEONGWOO, MOON, YOUNGOON, SYDORENKO, NADIYA

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Canadian Society of Surgical Oncology Nineteenth Annual Scientific MeetingWhat provider volume is appropriate for gastric cancer resection? Results of a RAND/UCLA expert panelSelf-... von Coburn, Natalie, Kreso, Antonija, Nadler, Ashlie, Hamilton, Trevor, Wei, Alice C., Smith, Myles J., Hebbard, Pamela, McConnell, Yarrow J., Nessim, Carolyn, Pathak, K. Alok, Quereshy, Fayez A., Dixon, Matthew, Mahar, Alyson, Paszat, Lawrence, McLeod, Robin, Law, Calvin, Swallow, Carol, Helyer, Lucy, Seevaratnam, Rajini, Cardoso, Roberta, van Galen, Peter, Davis, Thomas, Cao, Liangxian, Baiazitov, Ramil, Du, Wu, Sydorenko, Nadiya, Moon, Young-Choon, Szentgyorgyi, Eva, Gallinger, Steven, O’Brien, Catherine A., Dick, John E., Cukier, Moises, Singh, Simron, Milot, Laurent, Leuger, Derek, Kopachuk, Karen, Dixon, Elijah, Sutherland, Francis, Bathe, Oliver, Coburn, Natalie G., Devitt, Katharine S., Moulton, Carol-anne, Cleary, Sean P., Greig, Paul D., Heffron, Cynthia C., Rothwell, Jane R., Loftus, Barbara M., Jeffers, Michael, Geraghty, James G., Baxter, Nancy, Yun, Lingsong, Rakovitch, Eileen, Wright, Frances, Warner, Ellen, McCready, David, Hodgson, Nicole, Quan, May Lynn, Mack, Lloyd A., Temple, Walley J., McConnell, Yarrow, Sade, Shachar, McKinnon, Gregory, Mazurat, Andrea, Lambert, Pascal, Klonisch, Thomas C., Nason, Richard W., Poon, Jensen T.C., Law, W.L.

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