Medulloblastomics revisited: biological and clinical insights from thousands of patients von Hovestadt, Volker, Ayrault, Olivier, Swartling, Fredrik J., Robinson, Giles W., Pfister, Stefan M., Northcott, Paul A.

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Batch-normalization of cerebellar and medulloblastoma gene expression datasets utilizing empirically defined negative control genes von Weishaupt, Holger, Johansson, Patrik, Sundström, Anders, Lubovac-Pilav, Zelmina, Olsson, Björn, Nelander, Sven, Swartling, Fredrik J

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Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease von Hill, Rebecca M., Kuijper, Sanne, Lindsey, Janet C., Petrie, Kevin, Schwalbe, Ed C., Barker, Karen, Boult, Jessica K.R., Williamson, Daniel, Ahmad, Zai, Hallsworth, Albert, Ryan, Sarra L., Poon, Evon, Robinson, Simon P., Ruddle, Ruth, Raynaud, Florence I., Howell, Louise, Kwok, Colin, Joshi, Abhijit, Nicholson, Sarah Leigh, Crosier, Stephen, Ellison, David W., Wharton, Stephen B., Robson, Keith, Michalski, Antony, Hargrave, Darren, Jacques, Thomas S., Pizer, Barry, Bailey, Simon, Swartling, Fredrik J., Weiss, William A., Chesler, Louis, Clifford, Steven C.

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Distinct Neural Stem Cell Populations Give Rise to Disparate Brain Tumors in Response to N-MYC von Swartling, Fredrik J., Savov, Vasil, Persson, Anders I., Chen, Justin, Hackett, Christopher S., Northcott, Paul A., Grimmer, Matthew R., Lau, Jasmine, Chesler, Louis, Perry, Arie, Phillips, Joanna J., Taylor, Michael D., Weiss, William A.

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Utilizing the Dog Genome in the Search for Novel Candidate Genes Involved in Glioma Development-Genome Wide Association Mapping followed by Targeted Massive Parallel Sequencing Ide... von Truvé, Katarina, Dickinson, Peter, Xiong, Anqi, York, Daniel, Jayashankar, Kartika, Pielberg, Gerli, Koltookian, Michele, Murén, Eva, Fuxelius, Hans-Henrik, Weishaupt, Holger, Swartling, Fredrik J, Andersson, Göran, Hedhammar, Åke, Bongcam-Rudloff, Erik, Forsberg-Nilsson, Karin, Bannasch, Danika, Lindblad-Toh, Kerstin

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Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis von Huang, Miller, Tailor, Jignesh, Zhen, Qiqi, Gillmor, Aaron H., Miller, Matthew L., Weishaupt, Holger, Chen, Justin, Zheng, Tina, Nash, Emily K., McHenry, Lauren K., An, Zhenyi, Ye, Fubaiyang, Takashima, Yasuhiro, Clarke, James, Ayetey, Harold, Cavalli, Florence M.G., Luu, Betty, Moriarity, Branden S., Ilkhanizadeh, Shirin, Chavez, Lukas, Yu, Chunying, Kurian, Kathreena M., Magnaldo, Thierry, Sevenet, Nicolas, Koch, Philipp, Pollard, Steven M., Dirks, Peter, Snyder, Michael P., Largaespada, David A., Cho, Yoon Jae, Phillips, Joanna J., Swartling, Fredrik J., Morrissy, A. Sorana, Kool, Marcel, Pfister, Stefan M., Taylor, Michael D., Smith, Austin, Weiss, William A.

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Photoinduced Ring-Opening and Phototoxicity of an Indolin-3-one Derivative von Doloczki, Susanne, Kern, Christoph, Holmberg, Karl O, Swartling, Fredrik J, Streuff, Jan, Dyrager, Christine

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Targeting MYCN in Molecularly Defined Malignant Brain Tumors von Borgenvik, Anna, Čančer, Matko, Hutter, Sonja, Swartling, Fredrik J

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Combined BET bromodomain and CDK2 inhibition in MYC-driven medulloblastoma von Bolin, Sara, Borgenvik, Anna, Persson, Camilla U., Sundström, Anders, Qi, Jun, Bradner, James E., Weiss, William A., Cho, Yoon-Jae, Weishaupt, Holger, Swartling, Fredrik J.

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BET Bromodomain Inhibition of MYC-Amplified Medulloblastoma von BANDOPADHAYAY, Pratiti, BERGTHOLD, Guillaume, FURONG YU, NUJSAUBNUSI VUE, GIBSON, William J, PAOLELLA, Brenton R, MITRA, Siddhartha S, CHESHIER, Samuel H, JUN QI, LIU, Kun-Wei, WECHSLER-REYA, Robert, WEISS, William A, NGUYEN, Brian, SWARTLING, Fredrik J, KIERAN, Mark W, BRADNER, James E, BEROUKHIM, Rameen, CHO, Yoon-Jae, SCHUBERT, Simone, GHOLAMIN, Sharareh, YUJIE TANG, BOLIN, Sara, SCHUMACHER, Steven E, ZEID, Rhamy, MASOUD, Sabran

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ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors von Mainwaring, Oliver J., Weishaupt, Holger, Zhao, Miao, Rosén, Gabriela, Borgenvik, Anna, Breinschmid, Laura, Verbaan, Annemieke D., Richardson, Stacey, Thompson, Dean, Clifford, Steven C., Hill, Rebecca M., Annusver, Karl, Sundström, Anders, Holmberg, Karl O., Kasper, Maria, Hutter, Sonja, Swartling, Fredrik J.

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Medulloblastoma: experimental models and reality von Neumann, Julia E., Swartling, Fredrik J., Schüller, Ulrich

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Profiling chromatin accessibility in formalin-fixed paraffin-embedded samples von Zhang, Hua, Polavarapu, Vamsi Krishna, Xing, Pengwei, Zhao, Miao, Mathot, Lucy, Zhao, Linxuan, Rosen, Gabriela, Swartling, Fredrik J, Sjöblom, Tobias, Chen, Xingqi

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Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy von Čančer, Matko, Hutter, Sonja, Holmberg, Karl O., Rosén, Gabriela, Sundström, Anders, Tailor, Jignesh, Bergström, Tobias, Garancher, Alexandra, Essand, Magnus, Wechsler-Reya, Robert J., Falk, Anna, Weishaupt, Holger, Swartling, Fredrik J.

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The Irradiated Brain Microenvironment Supports Glioma Stemness and Survival via Astrocyte-Derived Transglutaminase 2 von Berg, Tracy J, Marques, Carolina, Pantazopoulou, Vasiliki, Johansson, Elinn, von Stedingk, Kristoffer, Lindgren, David, Jeannot, Pauline, Pietras, Elin J, Bergström, Tobias, Swartling, Fredrik J, Governa, Valeria, Bengzon, Johan, Belting, Mattias, Axelson, Håkan, Squatrito, Massimo, Pietras, Alexander

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FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma von Suryo Rahmanto, Aldwin, Savov, Vasil, Brunner, Andrä, Bolin, Sara, Weishaupt, Holger, Malyukova, Alena, Rosén, Gabriela, Čančer, Matko, Hutter, Sonja, Sundström, Anders, Kawauchi, Daisuke, Jones, David TW, Spruck, Charles, Taylor, Michael D, Cho, Yoon-Jae, Pfister, Stefan M, Kool, Marcel, Korshunov, Andrey, Swartling, Fredrik J, Sangfelt, Olle

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Modeling and Targeting MYC Genes in Childhood Brain Tumors von Hutter, Sonja, Bolin, Sara, Weishaupt, Holger, Swartling, Fredrik J

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Pleiotropic role for MYCN in medulloblastoma von Swartling, Fredrik J, Grimmer, Matthew R, Hackett, Christopher S, Northcott, Paul A, Fan, Qi-Wen, Goldenberg, David D, Lau, Jasmine, Masic, Selma, Nguyen, Kim, Yakovenko, Slava, Zhe, Xiao-Ning, Gilmer, Heather C Flynn, Collins, Rodney, Nagaoka, Mai, Phillips, Joanna J, Jenkins, Robert B, Tihan, Tarik, Vandenberg, Scott R, James, C David, Tanaka, Kohichi, Taylor, Michael D, Weiss, William A, Chesler, Louis

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Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma von Kahn, Suzana A., Wang, Xin, Nitta, Ryan T., Gholamin, Sharareh, Theruvath, Johanna, Hutter, Gregor, Azad, Tej D., Wadi, Lina, Bolin, Sara, Ramaswamy, Vijay, Esparza, Rogelio, Liu, Kun-Wei, Edwards, Michael, Swartling, Fredrik J., Sahoo, Debashis, Li, Gordon, Wechsler-Reya, Robert J., Reimand, Jüri, Cho, Yoon-Jae, Taylor, Michael D., Weissman, Irving L., Mitra, Siddhartha S., Cheshier, Samuel H.

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Development of an orthotopic medulloblastoma zebrafish model for rapid drug testing von van Bree, Niek, Oppelt, Ann-Sophie, Lindström, Susanne, Zhou, Leilei, Boutin, Lola, Coyle, Beth, Swartling, Fredrik J, Johnsen, John Inge, Bräutigam, Lars, Wilhelm, Margareta

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