Population PK and Exposure–Response Relationships for the Antibody–Drug Conjugate Brentuximab Vedotin in CTCL Patients in the Phase III ALCANZA Study von Suri, Ajit, Mould, Diane R., Liu, Yi, Jang, Graham, Venkatakrishnan, Karthik

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The safety, tolerability and pharmacokinetics of niraparib in Japanese patients with solid tumours: results of a phase I dose-escalation study von Yonemori, Kan, Shimizu, Toshio, Kondo, Shunsuke, Iwasa, Satoru, Koyama, Takafumi, Kitano, Shigehisa, Sato, Jun, Shimomura, Akihiko, Shibaki, Ryota, Suri, Ajit, Kase, Yoichi, Sumino, Shuuji, Tamura, Kenji, Yamamoto, Noboru

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Phase 2 single-arm study on the safety of maintenance niraparib in Japanese patients with platinum-sensitive relapsed ovarian cancer von Takehara, Kazuhiro, Matsumoto, Takashi, Hamanishi, Junzo, Hasegawa, Kosei, Matsuura, Motoki, Miura, Kiyonori, Nagao, Shoji, Nakai, Hidekatsu, Tanaka, Naotake, Tokunaga, Hideki, Ushijima, Kimio, Watari, Hidemichi, Yokoyama, Yoshihito, Kase, Yoichi, Sumino, Shuuji, Suri, Ajit, Itamochi, Hiroaki, Takeshima, Nobuhiro

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Phase 2 single-arm study on the efficacy and safety of niraparib in Japanese patients with heavily pretreated, homologous recombination-deficient ovarian cancer von Okamoto, Aikou, Kondo, Eiji, Nakamura, Toshiaki, Yanagida, Satoshi, Hamanishi, Junzo, Harano, Kenichi, Hasegawa, Kosei, Hirasawa, Takeshi, Hori, Kensuke, Komiyama, Shinichi, Matsuura, Motoki, Nakai, Hidekatsu, Nakamura, Hiroko, Sakata, Jun, Tabata, Tsutomu, Takehara, Kazuhiro, Takekuma, Munetaka, Yokoyama, Yoshihito, Kase, Yoichi, Sumino, Shuuji, Soeda, Junpei, Suri, Ajit, Aoki, Daisuke, Sugiyama, Toru

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Sustained Exposure to the Investigational Kisspeptin Analog, TAK-448, Down-Regulates Testosterone into the Castration Range in Healthy Males and in Patients With Prostate Cancer: R... von MacLean, David B, Matsui, Hisanori, Suri, Ajit, Neuwirth, Rachel, Colombel, Marc

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Population Pharmacokinetics of Brentuximab Vedotin in Adult and Pediatric Patients With Relapsed/Refractory Hematologic Malignancies: Model‐Informed Hypothesis Generation for Pedia... von Suri, Ajit, Mould, Diane R., Song, Gregory, Kinley, Judith, Venkatakrishnan, Karthik

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Effect of Food on the Pharmacokinetics, Safety, and Tolerability of Budesonide Oral Suspension in Healthy Adult Participants: A Randomized Phase 1 Study von Prokopienko, Alexander J, Wang, Junyao, Yajnik, Vijay, Baratta, Mike, Desai, Nirav K, Richmond, Camilla A, Suri, Ajit

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Phase II Study of Gemcitabine Monotherapy as a Salvage Treatment for Japanese Metastatic Breast Cancer Patients after Anthracycline and Taxane Treatment von Suzuki, Yasuhiro, Tokuda, Yutaka, Fujiwara, Yasuhiro, Iwata, Hiroji, Sasaki, Yasutsuna, Saji, Shigehira, Aogi, Kenjiro, Nambu, Yoshihiro, Suri, Ajit, Saeki, Toshiaki, Takashima, Shigemitsu

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Challenges and Opportunities in Dose Finding in Oncology and Immuno‐oncology von Ji, Yan, Jin, Jin Y., Hyman, David M., Kim, Geoffrey, Suri, Ajit

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Population Pharmacokinetic Modeling and Exposure–Response Assessment for the Antibody‐Drug Conjugate Brentuximab Vedotin in Hodgkin's Lymphoma in the Phase III ECHELON‐1 Study... von Suri, Ajit, Mould, Diane R., Song, Gregory, Collins, Graham P., Endres, Christopher J., Gomez‐Navarro, Jesús, Venkatakrishnan, Karthik

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Risk‐Based Pharmacokinetic and Drug–Drug Interaction Characterization of Antibody–Drug Conjugates in Oncology Clinical Development: An International Consortium for Innovation and Q... von Li, Chunze, Menon, Rajeev, Walles, Markus, Singh, Renu, Upreti, Vijay V., Brackman, Deanna, Lee, Anthony J., Endres, Christopher J., Kumar, Seema, Zhang, Donglu, Barletta, Frank, Suri, Ajit, Hainzl, Dominik, Liao, Kai H., Lalovic, Bojan, Beaumont, Maribel, Zuo, Peiying, Mayer, Andrew P., Wei, Dong

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Assessment of cytochrome P450-mediated drug-drug interaction potential of orteronel and exposure changes in patients with renal impairment using physiologically based pharmacokinet... von Lu, Chuang, Suri, Ajit, Shyu, Wen Chyi, Prakash, Shimoga

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Phase 1 Results from a Phase 1/2 Study to Assess the Safety, Tolerability and Recommended Phase 2 Dose (RP2D) of Brentuximab Vedotin Plus Doxorubicin, Vinblastine and Dacarbazine (... von Franklin, Anna, Zecca, Marco, Fagioli, Franca, Luisi, Flavio Augusto, Song, Gregory, Suri, Ajit, Leonard, E. Jane, Locatelli, Franco

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Brentuximab vedotin for paediatric relapsed or refractory Hodgkin's lymphoma and anaplastic large-cell lymphoma: a multicentre, open-label, phase 1/2 study von Locatelli, Franco, Mauz-Koerholz, Christine, Neville, Kathleen, Llort, Anna, Beishuizen, Auke, Daw, Stephen, Pillon, Marta, Aladjidi, Nathalie, Klingebiel, Thomas, Landman-Parker, Judith, Medina-Sanson, Aurora, August, Keith, Sachs, Jessica, Hoffman, Kristen, Kinley, Judith, Song, Sam, Song, Gregory, Zhang, Stephen, Suri, Ajit, Gore, Lia

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A phase 1 study of niraparib in Japanese patients with advanced solid tumors von Shibaki, Ryota, Shimizu, Toshio, Kondo, Shunsuke, Iwasa, Satoru, Koyama, Takafumi, Kitano, Shigehisa, Sato, Jun, Shimomura, Akihiko, Suri, Ajit, Kase, Yoichi, Sumino, Shuuji, Tamura, Kenji, Yamamoto, Noboru, Yonemori, Kan

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P1-198A phase 1 study of niraparib in Japanese patients with advanced solid tumors von Shibaki, Ryota, Shimizu, Toshio, Kondo, Shunsuke, Iwasa, Satoru, Koyama, Takafumi, Kitano, Shigehisa, Sato, Jun, Shimomura, Akihiko, Suri, Ajit, Kase, Yoichi, Sumino, Shuuji, Tamura, Kenji, Yamamoto, Noboru, Yonemori, Kan

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Relationships between food effects, patient adherence to treatment, and pharmacokinetics of oral anticancer drugs von Lin, Huamao Mark, Suri, Ajit, Webb, Iain James, Aggarwal, Saurabh

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Effect of omeprazole on the metabolism of cilostazol von Suri, A, Bramer, S L

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Su497 PHARMACOKINETICS (PK), SAFETY, AND EFFICACY OF INTRAVENOUS (IV) VEDOLIZUMAB IN PEDIATRIC PATIENTS WITH ULCERATIVE COLITIS OR CROHN'S DISEASE: RESULTS FROM THE PHASE 2 HUBBLE... von Hyams, Jeffrey S., Turner, Dan, Cohen, Stanley A., Szakos, Erzsébet, Kowalska-Duplaga, Kinga, Ruemmele, Frank, Croft, Nicholas M., Korczowski, Bartosz, Lawrence, Promise, Bhatia, Siddharth, Kadali, Harisha, Chen, Chunlin, Sun, Wan, Rosario, Maria, Suri, Ajit, Gulati, Parul, Treem, William, Rossiter, Guillermo, Lirio, Richard A.

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Niraparib in Japanese patients with platinum-sensitive recurrent ovarian cancer: final results of a multicenter phase 2 study von Itamochi, Hiroaki, Takeshima, Nobuhiro, Hamanishi, Junzo, Hasegawa, Kosei, Matsuura, Motoki, Miura, Kiyonori, Nagao, Shoji, Nakai, Hidekatsu, Tanaka, Naotake, Tokunaga, Hideki, Nishio, Shin, Watari, Hidemichi, Yokoyama, Yoshihito, Kase, Yoichi, Sumino, Shuuji, Kato, Ai, Suri, Ajit, Yasuoka, Toshiaki, Takehara, Kazuhiro

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