Dimethyl fumarate dosing in humans increases frataxin expression: A potential therapy for Friedreich's Ataxia von Jasoliya, Mittal, Sacca, Francesco, Sahdeo, Sunil, Chedin, Frederic, Pane, Chiara, Brescia Morra, Vincenzo, Filla, Alessandro, Pook, Mark, Cortopassi, Gino

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Precision genetic cellular models identify therapies protective against ER stress von Lebedeva, Irina V., Wagner, Michelle V., Sahdeo, Sunil, Lu, Yi-Fan, Anyanwu-Ofili, Anuli, Harms, Matthew B., Wadia, Jehangir S., Rajagopal, Gunaretnam, Boland, Michael J., Goldstein, David B.

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Development of an HTS assay for EPHX2 phosphatase activity and screening of nontargeted libraries von Morisseau, Christophe, Sahdeo, Sunil, Cortopassi, Gino, Hammock, Bruce D.

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Effects of alkyl side chain modification of coenzyme Q₁₀ on mitochondrial respiratory chain function and cytoprotection von Fash, David M, Khdour, Omar M, Sahdeo, Sunil J, Goldschmidt, Ruth, Jaruvangsanti, Jennifer, Dey, Sriloy, Arce, Pablo M, Collin, Valérie C, Cortopassi, Gino A, Hecht, Sidney M

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Isoproterenol acts as a biased agonist of the alpha-1A-adrenoceptor that selectively activates the MAPK/ERK pathway von Copik, Alicja J, Baldys, Aleksander, Nguyen, Khanh, Sahdeo, Sunil, Ho, Hoangdung, Kosaka, Alan, Dietrich, Paul J, Fitch, Bill, Raymond, John R, Ford, Anthony P D W, Button, Donald, Milla, Marcos E

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High-throughput screening of FDA-approved drugs using oxygen biosensor plates reveals secondary mitofunctional effects von Sahdeo, Sunil, Tomilov, Alexey, Komachi, Kelly, Iwahashi, Christine, Datta, Sandipan, Hughes, Owen, Hagerman, Paul, Cortopassi, Gino

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Translating amyotrophic lateral sclerosis genes into drug development leads von Sahdeo, Sunil, Goldstein, David B.

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Dimethyl fumarate mediates Nrf2-dependent mitochondrial biogenesis in mice and humans von Hayashi, Genki, Jasoliya, Mittal, Sahdeo, Sunil, Saccà, Francesco, Pane, Chiara, Filla, Alessandro, Marsili, Angela, Puorro, Giorgia, Lanzillo, Roberta, Brescia Morra, Vincenzo, Cortopassi, Gino

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In Vitro Evaluation of Mitochondrial Function and Estrogen Signaling in Cell Lines Exposed to the Antiseptic Cetylpyridinium Chloride von Datta, Sandipan, He, Guochun, Tomilov, Alexey, Sahdeo, Sunil, Denison, Michael S, Cortopassi, Gino

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Discovery of modulators of oxygen consumption for use in mitochondrial disease von Sahdeo, Sunil, Cortopassi, Gino

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Pharmacology of JNJ-28583113: A novel TRPM2 antagonist von Fourgeaud, Lawrence, Dvorak, Curt, Faouzi, Malika, Starkus, John, Sahdeo, Sunil, Wang, Qi, Lord, Brian, Coate, Heather, Taylor, Natalie, He, Yingbo, Qin, Ning, Wickenden, Alan, Carruthers, Nicholas, Lovenberg, Timothy W., Penner, Reinhold, Bhattacharya, Anindya

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Dyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia von Sahdeo, Sunil, Scott, Brian D, McMackin, Marissa Z, Jasoliya, Mittal, Brown, Brandon, Wulff, Heike, Perlman, Susan L, Pook, Mark A, Cortopassi, Gino A

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In Vitro and In Vivo Profile of GB001, a Potent and Selective DP2 Antagonist for the Treatment of Moderate-Severe Asthma von Meadows, Kristen Taylor, Murphy, Susan, Salter-Cid, Tomas, Sahdeo, Sunil, Opiteck, Gregory, Carter, Laura, Ortega, Hector, Salter-Cid, Luisa

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Coupling to Gq Signaling Is Required for Cardioprotection by an Alpha-1A-Adrenergic Receptor Agonist von Myagmar, Bat-Erdene, Ismaili, Taylor, Swigart, Philip M, Raghunathan, Anaha, Baker, Anthony J, Sahdeo, Sunil, Blevitt, Jonathan M, Milla, Marcos E, Simpson, Paul C

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Coupling to Gq Signaling Is Required for Cardioprotection by an Alpha-1A-Adrenergic Receptor Agonist von Myagmar, Bat-Erdene, Ismaili, Taylor, Swigart, Philip, Raghunathan, Anaha, Baker, Anthony, Sahdeo, Sunil, Blevitt, Jonathan, Milla, Marcos, Simpson, Paul

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A high-throughput screen for mitochondrial function reveals known and novel mitochondrial toxicants in a library of environmental agents von Datta, Sandipan, Sahdeo, Sunil, Gray, Jennifer A, Morriseau, Christophe, Hammock, Bruce D, Cortopassi, Gino

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Characterization of RO5126946, a Novel α7 Nicotinic Acetylcholine Receptor–Positive Allosteric Modulator von Sahdeo, Sunil, Wallace, Tanya, Hirakawa, Ryoko, Knoflach, Frederic, Bertrand, Daniel, Maag, Hans, Misner, Dinah, Tombaugh, Geoffrey C., Santarelli, Luca, Brameld, Ken, Milla, Marcos E., Button, Donald C.

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Development of an HTS assay for EPHX2 phosphatase activity and screening of non-targeted libraries von Morisseau, Christophe, Sahdeo, Sunil, Cortopassi, Gino, Hammock, Bruce D.

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Shc depletion stimulates brown fat activity in vivo and in vitro von Tomilov, Alexey, Bettaieb, Ahmed, Kim, Kyoungmi, Sahdeo, Sunil, Tomilova, Natalia, Lam, Adam, Hagopian, Kevork, Connell, Michelle, Fong, Jennifer, Rowland, Douglas, Griffey, Stephen, Ramsey, Jon, Haj, Fawaz, Cortopassi, Gino

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855 Diacylglycerol kinase alpha and zeta dual inhibitors enhance T cell responses and promote robust and durable anti-tumor T cell immunity von Steinberg, Marcos, Spasova, Darina, Eto, Danelle, Pferdekamper, AnneMarie, Nguyen, Phuong, Le, Brian, Naiman, Zachary, Murphy, Susan, Gozo, Maricel, Skipper, James, Taylor Ismaili, Liu, Xikui, Sahdeo, Sunil, Hu, Xiao, Isharat Yusuf, Kristen Taylor Meadows, Carter, Laura

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