Cellular Mechanisms of β -Amyloid Production and Secretion von Sinha, S, Lieberburg, I

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Partial Reduction of BACE1 Has Dramatic Effects on Alzheimer Plaque and Synaptic Pathology in APP Transgenic Mice von McConlogue, Lisa, Buttini, Manuel, Anderson, John P., Brigham, Elizabeth F., Chen, Karen S., Freedman, Stephen B., Games, Dora, Johnson-Wood, Kelly, Lee, Michael, Zeller, Michelle, Liu, Weiqun, Motter, Ruth, Sinha, Sukanto

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Plasma Kallikrein Mediates Retinal Vascular Dysfunction and Induces Retinal Thickening in Diabetic Rats von CLERMONT, Allen, CHILCOTE, TamieJ, KITA, Takeshi, JIA LIU, RIVA, Priscilla, SINHA, Sukanto, FEENER, Edward P

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Hyperglycemia-induced cerebral hematoma expansion is mediated by plasma kallikrein von Flaumenhaft, Robert, Clermont, Allen C, Gao, Ben-Bo, Blair, Price, Feener, Edward P, Liu, Jia, Sinha, Sukanto, Chilcote, Tamie J

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Plasma Kallikrein Mediates Angiotensin II Type 1 Receptor–Stimulated Retinal Vascular Permeability von Phipps, Joanna A, Clermont, Allen C, Sinha, Sukanto, Chilcote, Tamie J, Bursell, Sven-Erik, Feener, Edward P

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Design and synthesis of cell potent BACE-1 inhibitors: Structure–activity relationship of P1′ substituents von Sealy, Jennifer M., Truong, Anh P., Tso, Luke, Probst, Gary D., Aquino, Jose, Hom, Roy K., Jagodzinska, Barbara M., Dressen, Darren, Wone, David W.G., Brogley, Louis, John, Varghese, Tung, Jay S., Pleiss, Michael A., Tucker, John A., Konradi, Andrei W., Dappen, Michael S., Toth, Gergely, Pan, Hu, Ruslim, Lany, Miller, Jim, Bova, Michael P., Sinha, Sukanto, Quinn, Kevin P., Sauer, John-Michael

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Phosphorylation of Ser-129 Is the Dominant Pathological Modification of α-Synuclein in Familial and Sporadic Lewy Body Disease von Anderson, John P., Walker, Donald E., Goldstein, Jason M., de Laat, Rian, Banducci, Kelly, Caccavello, Russell J., Barbour, Robin, Huang, Jiping, Kling, Kristin, Lee, Michael, Diep, Linnea, Keim, Pamela S., Shen, Xiaofeng, Chataway, Tim, Schlossmacher, Michael G., Seubert, Peter, Schenk, Dale, Sinha, Sukanto, Gai, Wei Ping, Chilcote, Tamie J.

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The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II von Oltersdorf, Tilman, Fritz, Lawrence C, Schenk, Dale B, Lieberburg, Ivan, Johnson-Wood, Kelly L, Beattie, Eric C, Ward, Pamela J, Blacher, Russell W, Dovey, Harry F, Sinha, Sukanto

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BACE1 gene deletion: Impact on behavioral function in a model of Alzheimer's disease von Kobayashi, Dione, Zeller, Michelle, Cole, Tracy, Buttini, Manuel, McConlogue, Lisa, Sinha, Sukanto, Freedman, Stephen, Morris, Richard G.M, Chen, Karen S

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Therapeutic Approaches Related to Amyloid-.beta. Peptide and Alzheimer's Disease von Schenk, Dale B, Rydel, Russell E, May, Patrick, Little, Sheila, Panetta, Jill, Lieberburg, Ivan, Sinha, Sukanto

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Human β-Secretase (BACE) and BACE Inhibitors von John, Varghese, Beck, James P, Bienkowski, Michael J, Sinha, Sukanto, Heinrikson, Robert L

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Purification and cloning of amyloid precursor protein β-secretase from human brain von Sinha, Sukanto, Anderson, John P, Barbour, Robin, Basi, Guriqbal S, Caccavello, Russell, Davis, David, Doan, Minhtam, Dovey, Harry F, Frigon, Normand, Hong, Jin, Jacobson-Croak, Kirsten, Jewett, Nancy, Keim, Pamela, Knops, Jeroen, Lieberburg, Ivan, Power, Michael, Tan, Hua, Tatsuno, Gwen, Tung, Jay, Schenk, Dale, Seubert, Peter, Suomensaari, Susanna M, Wang, Shuwen, Walker, Donald, Zhao, Jun, McConlogue, Lisa, John, Varghese

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Design, Synthesis, and Crystal Structure of Hydroxyethyl Secondary Amine-Based Peptidomimetic Inhibitors of Human β-Secretase von Maillard, Michel C, Hom, Roy K, Benson, Timothy E, Moon, Joseph B, Mamo, Shumeye, Bienkowski, Michael, Tomasselli, Alfredo G, Woods, Danielle D, Prince, D. Bryan, Paddock, Donna J, Emmons, Thomas L, Tucker, John A, Dappen, Michael S, Brogley, Louis, Thorsett, Eugene D, Jewett, Nancy, Sinha, Sukanto, John, Varghese

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Antagonistic Effects of β-Site Amyloid Precursor Protein-cleaving Enzymes 1 and 2 on β-Amyloid Peptide Production in Cells von Basi, Guriqbal, Frigon, Normand, Barbour, Robin, Doan, Tam, Gordon, Grace, McConlogue, Lisa, Sinha, Sukanto, Zeller, Michelle

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The metabolism of the amyloid precursor protein and its relevance to Alzheimer's disease von Sinha, Sukanto

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Plasma Kallikrein Mediates Retinal Vascular Dysfunction and Induces Retinal Thickening in Diabetic Rats von Clermont, Allen Charles, Chilcote, Tamie J, Kita, Takeshi, Liu, Jia, Riva, Priscilla, Sinha, Sukanto, Feener, Edward Paul

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Design of Substrate-Based Inhibitors of Human β-Secretase von Tung, Jay S, Davis, David L, Anderson, John P, Walker, Don E, Mamo, Shumeye, Jewett, Nancy, Hom, Roy K, Sinha, Sukanto, Thorsett, Eugene D, John, Varghese

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Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids von Seubert, Peter, Vigo-Pelfrey, Carmen, Esch, Fred, Lee, Michael, Dovey, Harry, Davis, Dave, Sinha, Sukanto, Schiossmacher, Michael, Whaley, Justine, Swindlehurst, Cathy, McCormack, Robert, Wolfert, Robert, Selkoe, Dennis, Lieberburg, Ivan, Schenk, Dale

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The protease inhibitory properties of the Alzheimer's beta-amyloid precursor protein von SUKANTO SINHA, DOVEY, H. F, SEUBERT, P, WARD, P. J, BLACHER, R. W, BLABER, M, BRADSHAW, R. A, ARICI, L, MOBLEY, W. C, LIEBERBURG, I

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Design and Synthesis of Statine-Based Cell-Permeable Peptidomimetic Inhibitors of Human β-Secretase von Hom, Roy K, Fang, Larry Y, Mamo, Shumeye, Tung, Jay S, Guinn, Ashley C, Walker, Don E, Davis, David L, Gailunas, Andrea F, Thorsett, Eugene D, Sinha, Sukanto, Knops, Jeroen E, Jewett, Nancy E, Anderson, John P, John, Varghese

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