Antitumor activities of the targeted multi-tyrosine kinase inhibitor lenvatinib (E7080) against RET gene fusion-driven tumor models von Okamoto, Kiyoshi, Kodama, Kotaro, Takase, Kazuma, Sugi, Naoko Hata, Yamamoto, Yuji, Iwata, Masao, Tsuruoka, Akihiko

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Discovery of a potent and selective Axl inhibitor in preclinical model von Inoue, Satoshi, Yamane, Yoshinobu, Tsukamoto, Shuntaro, Azuma, Hiroshi, Nagao, Satoshi, Murai, Norio, Nishibata, Kyoko, Fukushima, Sayo, Ichikawa, Kenji, Nakagawa, Takayuki, Hata Sugi, Naoko, Ito, Daisuke, Kato, Yu, Goto, Aya, Kakiuchi, Dai, Ueno, Takashi, Matsui, Junji, Matsushima, Tomohiro

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Discovery of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine derivatives as novel selective Axl inhibitors von Inoue, Satoshi, Yamane, Yoshinobu, Tsukamoto, Shuntaro, Murai, Norio, Azuma, Hiroshi, Nagao, Satoshi, Nishibata, Kyoko, Fukushima, Sayo, Ichikawa, Kenji, Nakagawa, Takayuki, Hata Sugi, Naoko, Ito, Daisuke, Kato, Yu, Goto, Aya, Kakiuchi, Dai, Ueno, Takashi, Matsui, Junji, Matsushima, Tomohiro

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E7090, a Novel Selective Inhibitor of Fibroblast Growth Factor Receptors, Displays Potent Antitumor Activity and Prolongs Survival in Preclinical Models von Watanabe Miyano, Saori, Yamamoto, Yuji, Kodama, Kotaro, Miyajima, Yukiko, Mikamoto, Masaki, Nakagawa, Takayuki, Kuramochi, Hiroko, Funasaka, Setsuo, Nagao, Satoshi, Sugi, Naoko Hata, Okamoto, Kiyoshi, Minoshima, Yukinori, Nakatani, Yusuke, Karoji, Yuki, Ohashi, Isao, Yamane, Yoshinobu, Okada, Toshimi, Matsushima, Tomohiro, Matsui, Junji, Iwata, Masao, Uenaka, Toshimitsu, Tsuruoka, Akihiko

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Characterization of Rat Aortic Fragment within Collagen Gel as an Angiogenesis Model; Capillary Morphology may Reflect the Action Mechanisms of Angiogenesis Inhibitors von Hata-Sugi, Naoko, Kawase-Kageyama, Rena, Wakabayashi, Toshiaki

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Profiling Novel Sulfonamide Antitumor Agents with Cell-based Phenotypic Screens and Array-based Gene Expression Analysis von Yokoi, Akira, Kuromitsu, Junro, Kawai, Takatoshi, Nagasu, Takeshi, Sugi, Naoko Hata, Yoshimatsu, Kentaro, Yoshino, Hiroshi, Owa, Takashi

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A focused compound library of novel N-(7-indolyl)benzenesulfonamides for the discovery of potent cell cycle inhibitors von OWA, T, OKAUCHI, T, YOSHIMATSU, K, SUGI, N. H, OZAWA, Y, NAGASU, T, KOYANAGI, N, OKABE, T, KITOH, K, YOSHINO, H

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ER-851, a Novel Selective Inhibitor of AXL, Overcomes Resistance to Antimitotic Drugs von Tsukamoto, Shuntaro, Sugi, Naoko Hata, Nishibata, Kyoko, Nakazawa, Youya, Ito, Daisuke, Fukushima, Sayo, Nakagawa, Takayuki, Ichikawa, Kenji, Kato, Yu, Kakiuchi, Dai, Goto, Aya, Itoh-Yagi, Machiko, Aota, Tomoki, Inoue, Satoshi, Yamane, Yoshinobu, Murai, Norio, Azuma, Hiroshi, Nagao, Satoshi, Sasai, Ken, Akagi, Tsuyoshi, Imai, Toshio, Matsui, Junji, Matsushima, Tomohiro

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Abstract 3778: In vitro and in vivo characterization of E7090, a novel and selective FGFR inhibitor, for the treatment of endometrial cancer von Miyano, Saori Watanabe, Yamamoto, Yuji, Kodama, Kotaro, Sugi, Naoko Hata, Minoshima, Yukinori, Matsui, Junji, Iwata, Masao

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Synthesis and biological evaluation of N-(7-indolyl)-3-pyridinesulfonamide derivatives as potent antitumor agents von Owa, Takashi, Yoshino, Hiroshi, Okauchi, Tatsuo, Okabe, Tadashi, Ozawa, Yoichi, Hata Sugi, Naoko, Yoshimatsu, Kentaro, Nagasu, Takeshi, Koyanagi, Nozomu, Kitoh, Kyosuke

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Abstract 1376: Receptor tyrosine kinase (RTK) signaling pathway in preclinical thyroid cancer models: Antitumor and antiangiogenic activity of lenvatinib to target VEGFR/FGFR/RET von Tohyama, Osamu, Matsui, Junji, Kodama, Kotaro, Sugi, Naoko Hata, Kimura, Takayuki, Okamoto, Kiyoshi, Minoshima, Yukinori, Iwata, Masao, Funahashi, Yasuhiro

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An Angiogenesis Inhibitor E7820 Shows Broad-Spectrum Tumor Growth Inhibition in a Xenograft Model von Semba, Taro, Funahashi, Yasuhiro, Ono, Naoto, Yamamoto, Yuji, Sugi, Naoko Hata, Asada, Makoto, Yoshimatsu, Kentaro, Wakabayashi, Toshiaki

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Selective degradation of splicing factor CAPER[alpha] by anticancer sulfonamides von Uehara, Taisuke, Minoshima, Yukinori, Sagane, Koji, Sugi, Naoko Hata, Mitsuhashi, Kaoru Ogawa, Yamamoto, Noboru, Kamiyama, Hiroshi, Takahashi, Kentaro, Kotake, Yoshihiko, Uesugi, Mai, Yokoi, Akira, Inoue, Atsushi, Yoshida, Taku, Mabuchi, Miyuki, Tanaka, Akito, Owa, Takashi

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Anticancer Agent E7070 Inhibits Amino Acid and Uracil Transport in Fission Yeast von Tsukahara, K, Watanabe, T, Hata-Sugi, N, Yoshimatsu, K, Okayama, H, Nagasu, T

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An angiogenesis inhibitor E7820 shows broad-spectrum tumor growth inhibition in a xenograft model: Possible value of integrin α2 on platelets as a biological marker von SEMBA, Taro, FUNAHASHI, Yasuhiro, ONO, Naoto, YAMAMOTO, Yuji, SUGI, Naoko Hata, ASADA, Makoto, YOSHIMATSU, Kentaro, WAKABAYASHI, Toshiaki

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An angiogenesis inhibitor E7820 shows broad-spectrum tumor growth inhibition in a xenograft model: possible value of integrin alpha2 on platelets as a biological marker von Semba, Taro, Funahashi, Yasuhiro, Ono, Naoto, Yamamoto, Yuji, Sugi, Naoko Hata, Asada, Makoto, Yoshimatsu, Kentaro, Wakabayashi, Toshiaki

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Sulfonamide derivative, E7820, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium von Funahashi, Yasuhiro, Sugi, Naoko Hata, Semba, Taro, Yamamoto, Yuji, Hamaoka, Shinichi, Tsukahara-Tamai, Naoko, Ozawa, Yoichi, Tsuruoka, Akihiko, Nara, Kazumasa, Takahashi, Keiko, Okabe, Tadashi, Kamata, Junichi, Owa, Takashi, Ueda, Norihiro, Haneda, Toru, Yonaga, Masahiro, Yoshimatsu, Kentaro, Wakabayashi, Toshiaki

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ChemInform Abstract: A Focused Compound Library of Novel N-(7-Indolyl)benzenesulfonamides for the Discovery of Potent Cell Cycle Inhibitors von Owa, Takashi, Okauchi, Tatsuo, Yoshimatsu, Kentaro, Sugi, Naoko Hata, Ozawa, Yoichi, Nagasu, Takeshi, Koyanagi, Nozomu, Okabe, Tadashi, Kitoh, Kyosuke, Yoshino, Hiroshi

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