MK-8353: Discovery of an Orally Bioavailable Dual Mechanism ERK Inhibitor for Oncology von Boga, Sobhana Babu, Deng, Yongqi, Zhu, Liang, Nan, Yang, Cooper, Alan B., Shipps, Gerald W., Doll, Ronald, Shih, Neng-Yang, Zhu, Hugh, Sun, Robert, Wang, Tong, Paliwal, Sunil, Tsui, Hon-Chung, Gao, Xiaolei, Yao, Xin, Desai, Jagdish, Wang, James, Alhassan, Abdul Basit, Kelly, Joseph, Patel, Mehul, Muppalla, Kiran, Gudipati, Subrahmanyam, Zhang, Li-Kang, Buevich, Alexei, Hesk, David, Carr, Donna, Dayananth, Priya, Black, Stuart, Mei, Hong, Cox, Kathleen, Sherborne, Bradley, Hruza, Alan W., Xiao, Li, Jin, Weihong, Long, Brian, Liu, Gongjie, Taylor, Stacey A., Kirschmeier, Paul, Windsor, William T., Bishop, Robert, Samatar, Ahmed A.

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Discovery of 3(S)-thiomethyl pyrrolidine ERK inhibitors for oncology von Boga, Sobhana Babu, Alhassan, Abdul-Basit, Cooper, Alan B., Doll, Ronald, Shih, Neng-Yang, Shipps, Gerald, Deng, Yongqi, Zhu, Hugh, Nan, Yang, Sun, Robert, Zhu, Liang, Desai, Jagdish, Patel, Mehul, Muppalla, Kiran, Gao, Xiaolei, Wang, James, Yao, Xin, Kelly, Joseph, Gudipati, Subrahmanyam, Paliwal, Sunil, Tsui, Hon-Chung, Wang, Tong, Sherborne, Bradley, Xiao, Li, Hruza, Alan, Buevich, Alexei, Zhang, Li-Kang, Hesk, David, Samatar, Ahmed A., Carr, Donna, Long, Brian, Black, Stuart, Dayananth, Priya, Windsor, William, Kirschmeier, Paul, Bishop, Robert

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Structure-based drug design of clinical compound MK-8353, a novel inhibitor of ERK von Hruza, Alan, Boga, Sobhana Babu, Alhassan, Abdul-Basit, Cooper, Alan B., Doll, Ronald, Shih, Neng-Yang, Shipps, Gerald, Deng, Yongqi, Zhu, Hugh, Nan, Yang, Sun, Robert, Zhu, Liang, Desai, Jagdish, Patel, Mehul, Muppalla, Kiran, Gao, Xiaolei, Wang, James, Kelly, Joseph, Gudipati, Subrahmanyam, Paliwal, Sunil, Tsui, Hon-Chung, Wang, Tong, Sherborne, Bradley, Xiao, Li, Buevich, Alexei, Hesk, David, Samatar, Ahmed A., Carr, Donna, Long, Brian, Black, Stuart, Dayananth, Priya, Windsor, William, Kirschmeier, Paul, Bishop, Robert

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Alkenenitriles:  Conjugate Additions of Alkyl Iodides with a Silica-Supported Zinc−Copper Matrix in Water von Fleming, Fraser F, Gudipati, Subrahmanyam, Aitken, Jennifer A

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Alkenenitriles:  Zn−Cu Promoted Conjugate Additions of Alkyl Iodides in Water von Fleming, Fraser F, Gudipati, Subrahmanyam

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Cyclic Nitriles:  Diastereoselective Alkylations von Fleming, Fraser F, Gudipati, Subrahmanyam, Zhang, Zhiyu, Liu, Wang, Steward, Omar W

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Grignard Reagents:  Alkoxide-Directed Iodine−Magnesium Exchange at sp3 Centers von Fleming, Fraser F, Gudipati, Subrahmanyam, Vu, Viet Anh, Mycka, Robert J, Knochel, Paul

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Grignard Reagents:  Alkoxide-Directed Iodine−Magnesium Exchange at sp 3 Centers von Fleming, Fraser F., Gudipati, Subrahmanyam, Vu, Viet Anh, Mycka, Robert J., Knochel, Paul

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ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY von Su, Jing, Boyce, Christopher W, Wu, Heping, Hoover, Andrew J, Kim, Jae-Hun, Kelly, Joseph M, Lim, Yeon-Hee, Yu, Younong, Lo, Michael Man-Chu, Cumming, Jared N, Zhu, Xiaohong, Ali, Amjad, Huang, Xianhai, DeMong, Duane, Kuang, Rongze, Graham, Thomas H, Moreno, Jesus, Gudipati, Subrahmanyam, Xiao, Dong

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ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY von GUDIPATI, Subrahmanyam, CUMMING, Jared, N, MORENO, Jesus, ALI, Amjad, HOOVER, Andrew, J, ZHU, Xiaohong, DEMONG, Duane, HUANG, Xianhai, KIM, Jae-Hun, WU, Heping, YU, Younong, GRAHAM, Thomas, H, KUANG, Rongze, LIM, Yeon-Hee, SU, Jing, XIAO, Dong, BOYCE, Christopher, W, KELLY, Joseph, M, LO, Michael, Man-Chu

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ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY von GUDIPATI, Subrahmanyam, KELLY, Joseph, MORENO, Jesus, BOYCE, Christopher, GRAHAM, Thomas, ALI, Amjad, ZHU, Xiaohong, CUMMING, Jared, DEMONG, Duane, HUANG, Xianhai, KIM, Jae-Hun, WU, Heping, YU, Younong, KUANG, Rongze, LIM, Yeon-Hee, SU, Jing, XIAO, Dong, HOOVER, Andrew, LO, Michael

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Alkenenitriles: Zn-Cu Promoted Conjugate Additions of Alkyl Iodides in Water von Fleming, Fraser F., Gudipati, Subrahmanyam

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NOVEL COMPOUNDS THAT ARE ERK INHIBITORS von Gao, , Xiaolei, Lo, , Sie-Mun, Alhassan, , Abdul-Basit, Yao, , Xin, Zhu, , Liang, Boga, , Sobhana Babu, Wang, , James J-S, Zhu, , Hugh, Y, Gudipati, , Subrahmanyam, Shipps, , Gerald, W., Jr, Kelly, , Joseph, M, Deng, , Yongqi, Cooper, , Alan, B, Desai, , Jagdish, A

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ChemInform Abstract: Alkenenitriles: Conjugate Additions of Alkyl Iodides with a Silica-Supported Zinc-Copper Matrix in Water von Fleming, Fraser F., Gudipati, Subrahmanyam, Aitken, Jennifer A.

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Compuestos que son inhibidores de las ERK von GUDIPATI, Subrahmanyam, PALIWAL, Sunil, DOLL, Ronald J, DENG, Yongqi, SHIH, Neng-Yang, ZHU, Hugh Y, SAMATAR, A. Ahmed, BOGA, Sobhana Babu, PATEL, Mehul F, DESAI, Jagdish A, ALHASSAN, Abdul-Basit, KELLY, Joseph M, WANG, James J-S, COOPER, Alan B, ZHU, Liang, NAN, Yang, TSUI, Hon-Chung, GAO, Xiaolei, YAO, Xin, SHIPPS, Gerald W

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ChemInform Abstract: Grignard Reagents: Alkoxide‐Directed Iodine—Magnesium Exchange at sp 3 Centers von Fleming, Fraser F., Gudipati, Subrahmanyam, Vu, Viet Anh, Mycka, Robert J., Knochel, Paul

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ChemInform Abstract: Grignard Reagents: Alkoxide-Directed Iodine-Magnesium Exchange at sp3 Centers von Fleming, Fraser F., Gudipati, Subrahmanyam, Vu, Viet Anh, Mycka, Robert J., Knochel, Paul

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COMPOUNDS THAT ARE ERK INHIBITORS von GUDIPATI, Subrahmanyam, PALIWAL, Sunil, DOLL, Ronald J, DENG, Yongqi, DESAI, Jagdish, A, SHIPPS, Gerald W., Jr, ZHU, Hugh, Y, BOGA, Sobhana, Babu, COOPER, Alan, B, SHIH, Neng-Yang, PATEL, Mehul, F, ALHASSAN, Abdul-Basit, KELLY, Joseph, M, WANG, James, J-S, ZHU, Liang, NAN, Yang, TSUI, Hon-Chung, GAO, Xiaolei, YAO, Xin, SAMATAR, A.Ahmed

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Compounds that are ERK inhibitors von ZHU HUGH Y, KELLY JOSEPH M, WANG JAMES J-S, DENG YONGQI, ALHASSAN ABDUL-BASIT, DESAI JAGDISH A, LO SIE-MUN, YAO XIN, ZHU LIANG, SHIPPS, JR. GERALD W, COOPER ALAN B, GAO XIAOLEI, BOGA SOBHANA BABU, GUDIPATI SUBRAHMANYAM

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Cyclic Nitriles: Diastereoselective Alkylations von Fleming, Fraser F., Gudipati, Subrahmanyam, Zhang, Zhiyu, Liu, Wang, Steward, Omar W.

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