Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2 von Verma, Sharad K, Tian, Xinrong, LaFrance, Louis V, Duquenne, Céline, Suarez, Dominic P, Newlander, Kenneth A, Romeril, Stuart P, Burgess, Joelle L, Grant, Seth W, Brackley, James A, Graves, Alan P, Scherzer, Daryl A, Shu, Art, Thompson, Christine, Ott, Heidi M, Aller, Glenn S. Van, Machutta, Carl A, Diaz, Elsie, Jiang, Yong, Johnson, Neil W, Knight, Steven D, Kruger, Ryan G, McCabe, Michael T, Dhanak, Dashyant, Tummino, Peter J, Creasy, Caretha L, Miller, William H

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Inhibition Of LSD1 As a Therapeutic Strategy For The Treatment Of Acute Myeloid Leukemia von Kruger, Ryan G., Mohammad, Helai, Smitheman, Kimberly, Cusan, Monica, Liu, Yan, Pappalardi, Melissa, Federowicz, Kelly, Van Aller, Glenn, Kasparec, Jiri, Tian, Xinrong, Suarez, Dominic, Rouse, Meagan, Schneck, Jessica, Carson, Jeffrey, McDevitt, Patrick, Ho, Thau, McHugh, Charles, Miller, William, Johnson, Neil, Armstrong, Scott A., Tummino, Peter

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Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors von Goodman, Krista B., Bury, Michael J., Cheung, Mui, Cichy-Knight, Maria A., Dowdell, Sarah E., Dunn, Allison K., Lee, Dennis, Lieby, Jeffrey A., Moore, Michael L., Scherzer, Daryl A., Sha, Deyou, Suarez, Dominic P., Murphy, Dennis J., Harpel, Mark R., Manas, Eric S., McNulty, Dean E., Annan, Roland S., Matico, Rosalie E., Schwartz, Benjamin K., Trill, John J., Sweitzer, Thomas D., Wang, Da-yuan, Keller, Paul M., Krawiec, John A., Jaye, Michael C.

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Discovery of Proline-Based p300/CBP Inhibitors Using DNA-Encoded Library Technology in Combination with High-Throughput Screening von Tian, Xinrong, Suarez, Dominic, Thomson, Douglas, Li, William, King, Elizabeth A., LaFrance, Louis, Boehm, Jeffrey, Barton, Linda, Di Marco, Christina, Martyr, Cuthbert, Thalji, Reema, Medina, Jesus, Knight, Steven, Heerding, Dirk, Gao, Enoch, Nartey, Eldridge, Cecconie, Ted, Nixon, Christopher, Zhang, Guofeng, Berrodin, Thomas J., Phelps, Christopher, Patel, Amish, Bai, Xiaopeng, Lind, Ken, Prabhu, Ninad, Messer, Jeffrey, Zhu, Zhengrong, Shewchuk, Lisa, Reid, Rob, Graves, Alan P., McHugh, Charles, Mangatt, Biju

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An efficient and practical synthesis of 2,4-substituted pyrido[4,3-d]pyrimidin-5(6H)-ones von Tian, Xinrong, Suarez, Dominic P., Li, William Hoi Hong, McSherry, Allison K., Sanchez, Robert M., Moore, Michael L., Axten, Jeffrey M.

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Cell-Based Drug Discovery: Identification and Optimization of Small Molecules that Reduce c‑MYC Protein Levels in Cells von Medina, Jesús R, Tian, Xinrong, Li, William H, Suarez, Dominic, Mack, James F, LaFrance, Louis, Martyr, Cuthbert, Brackley, James, Di Marco, Christina, Rivero, Ralph, Heerding, Dirk A, McHugh, Charles, Minthorn, Elisabeth, Bhaskar, Aishwarya, Rubin, Jacob, Butticello, Michael, Carpenter, Christopher, Nartey, Eldridge N, Berrodin, Thomas J, Kallal, Lorena A, Mangatt, Biju

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New generation of protox-inhibiting herbicides von Theodoridis, George, Bahr, James T, Hotzman, Frederick W, Saroj Sehgel, Suarez, Dominic P

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Abstract 3513: Inhibition of LSD1 for the treatment of cancer von Smitheman, Kimberly, Cusan, Monica, Liu, Yan, Butticello, Michael, Pappalardi, Melissa, Foley, James, Federowicz, Kelly, Van Aller, Glenn, Kasparec, Jiri, Tian, Xinrong, Suarez, Dominic, Schneck, Jess, Carson, Jeff, McDevitt, Patrick, Ho, Thau, McHugh, Charles, Miller, William, Armstrong, Scott, Hann, Christine, Johnson, Neil, Kruger, Ryan G., Mohammad, Helai P., Kamat, Shekhar

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Abstract 5379: A potent EZH2 inhibitor exhibits long residence time and anti-tumor activity von Ott, Heidi, van Aller, Glenn, Ward, Jessica, Le, BaoChau, Rominger, Cynthia, Foley, James, Korenchuk, Susan, McHugh, Charles, Butticello, Michael, Blackledge, Charles, Brackley, James, Burgess, Joelle, Duquenne, Celine, Johnson, Neil, Kasparec, Jiri, LaFrance, Louis, Li, Mei, McNulty, Kenneth, Newlander, Kenneth, Romeril, Stuart, Schmidt, Stanley, Schulz, Mark, Su, Dai-Shi, Suarez, Dominic, Tian, Xinrong, Carpenter, Christopher, Luengo, Juan, Kruger, Ryan, Knight, Steven, McCabe, Michael T.

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Abstract 2939: Discovery and synthesis of highly potent and selective small molecule inhibitors of the histone methyltransferase EZH2 von Verma, Sharad K., LaFrance, Louis V., Tian, Xinrong, Newlander, Ken, Duquenne, Céline, Suarez, Dominic, Knight, Steven D., Burgess, Joelle, Brackley, James, Johnson, Neil W., Graves, Alan P., Mellinger, Mark, Romeril, Stuart, Grant, Seth W., Scherzer, Daryl, Shu, Art, Creasy, Caretha L., Kruger, Ryan, Diaz, Elsie, Le, Baochau, Thompson, Christine, Morgan-Ott, Heidi, McCabe, Michael T., McHugh, Charles F., Miller, William H., Tummino, Peter, Dhanak, Dash

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CYCLOPROPYLAMINES AS LSD1 INHIBITORS von SUAREZ, Dominic, JOHNSON, Neil, W, KASPAREC, Jiri, TIAN, Xinrong, MILLER, William, Henry, ROUSE, Meagan, B

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CYCLOPROPYLAMINES AS LSD1 INHIBITORS von Jiri KASPAREC, Meagan B. ROUSE, William Henry MILLER, Neil W. JOHNSON, Xinrong TIAN, Dominic SUAREZ

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CYCLOPROPYLAMINES AS LSD1 INHIBITORS von MILLER, WILLIAM HENRY, TIAN, XINRONG, JOHNSON, NEIL W, KASPAREC, JIRI, SUAREZ, DOMINIC, ROUSE, MEAGAN B

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CYCLOPROPYLAMINES AS LSD1 INHIBITORS von MILLER, WILLIAM HENRY, TIAN, XINRONG, JOHNSON, NEIL W, KASPAREC, JIRI, SUAREZ, DOMINIC, ROUSE, MEAGAN B

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Compostos de ciclopropilaminas como inibidores lsd1 e composições farmacêuticas compreendendo ditos compostos von KASPAREC JIRI, TIAN XINRONG, SUAREZ DOMINIC, MEAGAN B. ROUSE, WILLIAM HENRY MILLER, NEIL W. JOHNSON

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Cyclopropylamines as LSD1 inhibitors von KASPAREC JIRI, TIAN XINRONG, SUAREZ DOMINIC, ROUSE MEAGAN B, MILLER WILLIAM HENRY, JOHNSON NEIL W

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Cyclopropylamines as LSD1 inhibitors von MILLER, WILLIAM HENRY, TIAN, XINRONG, JOHNSON, NEIL W, KASPAREC, JIRI, SUAREZ, DOMINIC, ROUSE, MEAGAN B

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Cyclopropylamines as lsd1 inhibitors von KASPAREC JIRI, TIAN XINRONG, SUAREZ DOMINIC, ROUSE MEAGAN B, MILLER WILLIAM HENRY, JOHNSON NEIL W

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CYCLOPROPYLAMINES AS LSD1 INHIBITORS von TIAN, XINRONG, KASPAREC, JIRI, ROUSE, MEAGAN, B, JOHNSON, NEIL, W, SUAREZ, DOMINIC, MILLER, WILLIAM, HENRY

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CYCLOPROPYLAMINES AS LSD1 INHIBITORS von KASPAREC JIRI, TIAN XINRONG, SUAREZ DOMINIC, ROUSE MEAGAN B, MILLER WILLIAM HENRY, JOHNSON NEIL W

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