Efficacy and safety of tralokinumab in patients with severe uncontrolled asthma: a randomised, double-blind, placebo-controlled, phase 2b trial von Brightling, Christopher E, Prof, Chanez, Pascal, Prof, Leigh, Richard, MBChB, O'Byrne, Paul M, Prof, Korn, Stephanie, PhD, She, Dewei, PhD, May, Richard D, PhD, Streicher, Katie, PhD, Ranade, Koustubh, PhD, Piper, Edward, Dr

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The Pathogenesis, Molecular Mechanisms, and Therapeutic Potential of the Interferon Pathway in Systemic Lupus Erythematosus and Other Autoimmune Diseases von Ramaswamy, Madhu, Tummala, Raj, Streicher, Katie, Nogueira da Costa, Andre, Brohawn, Philip Z.

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Genomic Landscape Survey Identifies SRSF1 as a Key Oncodriver in Small Cell Lung Cancer von Jiang, Liyan, Huang, Jiaqi, Higgs, Brandon W, Hu, Zhibin, Xiao, Zhan, Yao, Xin, Conley, Sarah, Zhong, Haihong, Liu, Zheng, Brohawn, Philip, Shen, Dong, Wu, Song, Ge, Xiaoxiao, Jiang, Yue, Zhao, Yizhuo, Lou, Yuqing, Morehouse, Chris, Zhu, Wei, Sebastian, Yinong, Czapiga, Meggan, Oganesyan, Vaheh, Fu, Haihua, Niu, Yanjie, Zhang, Wei, Streicher, Katie, Tice, David, Zhao, Heng, Zhu, Meng, Xu, Lin, Herbst, Ronald, Su, Xinying, Gu, Yi, Li, Shyoung, Huang, Lihua, Gu, Jianren, Han, Baohui, Jallal, Bahija, Shen, Hongbing, Yao, Yihong

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Inhibition of Myogenic MicroRNAs 1, 133, and 206 by Inflammatory Cytokines Links Inflammation and Muscle Degeneration in Adult Inflammatory Myopathies von Georgantas, Robert W., Streicher, Katie, Greenberg, Steven A., Greenlees, Lydia M., Zhu, Wei, Brohawn, Philip Z., Higgs, Brandon W., Czapiga, Meggan, Morehouse, Christopher A., Amato, Anthony, Richman, Laura, Jallal, Bahija, Yao, Yihong, Ranade, Koustubh

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Intramuscular AZD7442 (Tixagevimab–Cilgavimab) for Prevention of Covid-19 von Levin, Myron J., Ustianowski, Andrew, De Wit, Stéphane, Launay, Odile, Avila, Miles, Templeton, Alison, Yuan, Yuan, Seegobin, Seth, Ellery, Adam, Levinson, Dennis J., Ambery, Philip, Arends, Rosalinda H., Beavon, Rohini, Dey, Kanika, Garbes, Pedro, Kelly, Elizabeth J., Koh, Gavin C.K.W., Near, Karen A., Padilla, Kelly W., Psachoulia, Konstantina, Sharbaugh, Audrey, Streicher, Katie, Pangalos, Menelas N., Esser, Mark T.

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Anti-PD-L1 and anti-CD73 combination therapy promotes T cell response to EGFR-mutated NSCLC von Tu, Eric, McGlinchey, Kelly, Wang, Jixin, Martin, Philip, Ching, Steven Lk, Floc'h, Nicolas, Kurasawa, James, Starrett, Jacqueline H, Lazdun, Yelena, Wetzel, Leslie, Nuttall, Barrett, Ng, Felicia Sl, Coffman, Karen T, Smith, Paul D, Politi, Katerina, Cooper, Zachary A, Streicher, Katie

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Mammary gland immunity and mastitis susceptibility von Sordillo, Lorraine M, Streicher, Katie L

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MicroRNA-206 induces G1 arrest in melanoma by inhibition of CDK4 and Cyclin D von Georgantas III, Robert W., Streicher, Katie, Luo, Xiaobing, Greenlees, Lydia, Zhu, Wei, Liu, Zheng, Brohawn, Philip, Morehouse, Christopher, Higgs, Brandon W., Richman, Laura, Jallal, Bahija, Yao, Yihong, Ranade, Koustubh

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Multiple interacting oncogenes on the 8p11-p12 amplicon in human breast cancer von ZENG QUAN YANG, STREICHER, Katie L, RAY, Michael E, ABRAMS, Judith, ETHIER, Stephen P

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Efficacy, Safety, and Pharmacokinetics of AZD7442 (Tixagevimab/Cilgavimab) for Prevention of Symptomatic COVID-19: 15-Month Final Analysis of the PROVENT and STORM CHASER Trials von Levin, Myron J., Ustianowski, Andrew, De Wit, Stephane, Beavon, Rohini, Thissen, Jesse, Seegobin, Seth, Dey, Kanika, Near, Karen A., Streicher, Katie, Kiazand, Alexandre, Esser, Mark T.

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Molecular Characterization of AZD7442 (Tixagevimab-Cilgavimab) Neutralization of SARS-CoV-2 Omicron Subvariants von Roe, Tiffany L, Brady, Tyler, Schuko, Nicolette, Nguyen, Amy, Beloor, Jagadish, Guest, Johnathan D, Aksyuk, Anastasia A, Tuffy, Kevin M, Zhang, Tianhui, Streicher, Katie, Kelly, Elizabeth J, Kijak, Gustavo H

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Effect of Tezepelumab on the Humoral Immune Response to Seasonal Quadrivalent Influenza Vaccination in Patients with Moderate to Severe Asthma: The Phase 3b VECTOR Study von Cole, Jeremy, Cąpała-Szczurko, Iwona, Roseti, Stephanie, Chen, Claudia, Caveney, Scott, Aksyuk, Anastasia A., Streicher, Katie, Ponnarambil, Sandhia, Colice, Gene

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Safety, Efficacy and Pharmacokinetics of AZD7442 (Tixagevimab/Cilgavimab) for Treatment of Mild-to-Moderate COVID-19: 15-Month Final Analysis of the TACKLE Trial von Hobbs, F. D. Richard, Montgomery, Hugh, Padilla, Francisco, Simón-Campos, Jesus Abraham, Arbetter, Douglas, Seegobin, Seth, Kiazand, Alexandre, Streicher, Katie, Martinez-Alier, Nuria, Cohen, Taylor S., Esser, Mark T.

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Outpatient Treatment with AZD7442 (Tixagevimab/Cilgavimab) Prevented COVID-19 Hospitalizations over 6 Months and Reduced Symptom Progression in the TACKLE Randomized Trial von Hobbs, F. D. Richard, Montgomery, Hugh, Padilla, Francisco, Simón-Campos, Jesus Abraham, Kim, Kenneth, Arbetter, Douglas, Padilla, Kelly W., Reddy, Venkatesh Pilla, Seegobin, Seth, Streicher, Katie, Templeton, Alison, Viani, Rolando M., Johnsson, Eva, Koh, Gavin C. K. W., Esser, Mark T.

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Increased CD73 and reduced IFNG signature expression in relation to response rates to anti-PD-1(L1) therapies in EGFR-mutant NSCLC von Streicher, Katie, Higgs, Brandon W., Wu, Song, Coffman, Karen, Damera, Gautam, Durham, Nick, Greenlees, Lydia, Lazdun, Yelena, Cheng, Li, Cooper, Zachary, Ranade, Koustubh

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Serum AZD7442 (tixagevimab–cilgavimab) concentrations and in vitro IC50 values predict SARS‐CoV‐2 neutralising antibody titres von Clegg, Lindsay E, Stepanov, Oleg, Matthews, Sam, White, Tom, Seegobin, Seth, Thomas, Steven, Tuffy, Kevin M, Någård, Mats, Esser, Mark T, Streicher, Katie, Cohen, Taylor S, Aksyuk, Anastasia A

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Analysis of SARS-CoV-2 Emergent Variants Following AZD7442 (Tixagevimab/Cilgavimab) for Early Outpatient Treatment of COVID-19 (TACKLE Trial) von Kijak, Gustavo H., Ahani, Bahar, Arbetter, Douglas, Chuecos, Fernando, Gopalakrishnan, Vancheswaran, Beloor, Jagadish, Brady, Tyler, Nguyen, Amy, Roe, Tiffany L., Schuko, Nicolette, Zhang, Tianhui, Hobbs, F. D. Richard, Padilla, Francisco, Kelly, Elizabeth J., Montgomery, Hugh, Streicher, Katie

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Altered expression of insulin receptor isoforms in breast cancer von Huang, Jiaqi, Morehouse, Chris, Streicher, Katie, Higgs, Brandon W, Gao, Jin, Czapiga, Meggan, Boutrin, Anmarie, Zhu, Wei, Brohawn, Philip, Chang, Yong, Viner, Jaye, LaVallee, Theresa, Richman, Laura, Jallal, Bahija, Yao, Yihong

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Qualification of a Biolayer Interferometry Assay to Support AZD7442 Resistance Monitoring von Brady, Tyler, Zhang, Tianhui, Tuffy, Kevin M, Haskins, Nantaporn, Du, Qun, Lin, Jia, Kaplan, Gilad, Novick, Steven, Roe, Tiffany L, Ren, Kuishu, Rosenthal, Kim, McTamney, Patrick M, Abram, Michael E, Streicher, Katie, Kelly, Elizabeth J

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Development of a new ARCHITECT automated periostin immunoassay von Jeanblanc, Nicolette M., Hemken, Philip M., Datwyler, Maria J., Brophy, Susan E., Manetz, T. Scott, Lee, Rozanne, Liang, Meina, Chowdhury, Partha S., Varkey, Reena, Grant, Ethan P., Streicher, Katie, Greenlees, Lydia, Ranade, Koustubh, Davis, Gerard J.

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