Facilitating the use of the target product profile in academic research: a systematic review von Ibnidris, Aliaa, Liaskos, Nektarios, Eldem, Ece, Gunn, Angus, Streffer, Johannes, Gold, Michael, Rea, Mike, Teipel, Stefan, Gardiol, Alejandra, Boccardi, Marina

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Regional brain mGlu5 receptor occupancy following single oral doses of mavoglurant as measured by [11C]-ABP688 PET imaging in healthy volunteers von Streffer, Johannes, Treyer, Valerie, Buck, Alfred, Ametamey, Simon M., Blagoev, Milen, Maguire, Ralph P, Gautier, Aurélie, Auberson, Yves P., Schmidt, Mark E., Vranesic, Ivan-Toma, Gomez-Mancilla, Baltazar, Gasparini, Fabrizio

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Allosteric alpha-7 nicotinic receptor modulation and P50 sensory gating in schizophrenia: A proof-of-mechanism study von Winterer, Georg, Gallinat, Jürgen, Brinkmeyer, Jürgen, Musso, Francesco, Kornhuber, Johannes, Thuerauf, Norbert, Rujescu, Dan, Favis, Reyna, Sun, Yu, Franc, Monique A., Ouwerkerk-Mahadevan, Sivi, Janssens, Luc, Timmers, Maarten, Streffer, Johannes R.

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Antibodies against β-Amyloid Slow Cognitive Decline in Alzheimer's Disease von Hock, Christoph, Konietzko, Uwe, Streffer, Johannes R, Tracy, Jay, Signorell, Andri, Müller-Tillmanns, Britta, Lemke, Ulrike, Henke, Katharina, Moritz, Eva, Garcia, Esmeralda, Wollmer, M.Axel, Umbricht, Daniel, de Quervain, Dominique J.F, Hofmann, Marc, Maddalena, Alessia, Papassotiropoulos, Andreas, Nitsch, Roger M

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Reproducibility, reliability and variability of FA and MD in the older healthy population: A test-retest multiparametric analysis von Luque Laguna, Pedro A., Combes, Anna J.E., Streffer, Johannes, Einstein, Steven, Timmers, Maarten, Williams, Steve C.R., Dell'Acqua, Flavio

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Test-retest reliability of time-varying patterns of brain activity across single band and multiband resting-state functional magnetic resonance imaging in healthy older adults von Cahart, Marie-Stephanie, Dell'Acqua, Flavio, Giampietro, Vincent, Cabral, Joana, Timmers, Maarten, Streffer, Johannes, Einstein, Steven, Zelaya, Fernando, Williams, Steven C R, O'Daly, Owen

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Decreased Deposition of Beta-Amyloid 1-38 and Increased Deposition of Beta-Amyloid 1-42 in Brain Tissue of Presenilin-1 E280A Familial Alzheimer’s Disease Patients von Dinkel, Felix, Trujillo-Rodriguez, Diana, Villegas, Andres, Streffer, Johannes, Mercken, Marc, Lopera, Francisco, Glatzel, Markus, Sepulveda-Falla, Diego

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Impaired trunk stability in individuals at high risk for Parkinson's disease von Maetzler, Walter, Mancini, Martina, Liepelt-Scarfone, Inga, Müller, Katharina, Becker, Clemens, van Lummel, Rob C, Ainsworth, Erik, Hobert, Markus, Streffer, Johannes, Berg, Daniela, Chiari, Lorenzo

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Long-term safety and tolerability of atabecestat (JNJ-54861911), an oral BACE1 inhibitor, in early Alzheimer's disease spectrum patients: a randomized, double-blind, placebo-contro... von Novak, Gerald, Streffer, Johannes Rolf, Timmers, Maarten, Henley, David, Brashear, H Robert, Bogert, Jennifer, Russu, Alberto, Janssens, Luc, Tesseur, Ina, Tritsmans, Luc, Van Nueten, Luc, Engelborghs, Sebastiaan

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The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimer's pathology von Westwood, Sarah, Liu, Benjamine, Baird, Alison L, Anand, Sneha, Nevado-Holgado, Alejo J, Newby, Danielle, Pikkarainen, Maria, Hallikainen, Merja, Kuusisto, Johanna, Streffer, Johannes R, Novak, Gerald, Blennow, Kaj, Andreasson, Ulf, Zetterberg, Henrik, Smith, Ulf, Laakso, Markku, Soininen, Hilkka, Lovestone, Simon

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Something Is Better Than Nothing: The Value of Active Intervention in Stated Preferences for Treatments to Delay Onset of Alzheimer's Disease Symptoms von Johnson, F. Reed, PhD, DiSantostefano, Rachael L., MS, PhD, Yang, Jui-Chen, MEM, Reed, Shelby D., PhD, Streffer, Johannes, MD, Levitan, Bennett, MD, PhD

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Zilucoplan in patients with acute hypoxic respiratory failure due to COVID-19 (ZILU-COV): A structured summary of a study protocol for a randomised controlled trial von Declercq, Jozefien, Bosteels, Cedric, Van Damme, Karel, De Leeuw, Elisabeth, Maes, Bastiaan, Vandecauter, Ans, Vermeersch, Stefanie, Delporte, Anja, Demeyere, Bénédicte, Vuylsteke, Marnik, Lalla, Marianna, Smart, Trevor, Detalle, Laurent, Bouw, René, Streffer, Johannes, Degeeter, Thibo, Vergotte, Marie, Guisez, Tanguy, Van Braeckel, Eva, Van Der Straeten, Catherine, Lambrecht, Bart N

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Pharmacodynamics of atabecestat (JNJ-54861911), an oral BACE1 inhibitor in patients with early Alzheimer's disease: randomized, double-blind, placebo-controlled study von Timmers, Maarten, Streffer, Johannes Rolf, Russu, Alberto, Tominaga, Yushin, Shimizu, Hiroko, Shiraishi, Ayako, Tatikola, Kanaka, Smekens, Pascale, Börjesson-Hanson, Anne, Andreasen, Niels, Matias-Guiu, Jorge, Baquero, Miquel, Boada, Mercè, Tesseur, Ina, Tritsmans, Luc, Van Nueten, Luc, Engelborghs, Sebastiaan

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Executive Function Is Related to the Urinary Urgency in Non-demented Patients With Parkinson's Disease von Tkaczynska, Zuzanna, Becker, Sara, Maetzler, Walter, Timmers, Maarten, Van Nueten, Luc, Sulzer, Patricia, Salvadore, Giacomo, Schäffer, Eva, Brockmann, Kathrin, Streffer, Johannes, Berg, Daniela, Liepelt-Scarfone, Inga

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Normative data from linear and nonlinear quantile regression in CANTAB: Cognition in mid-to-late life in an epidemiological sample von Abbott, Rosemary A., Skirrow, Caroline, Jokisch, Martha, Timmers, Maarten, Streffer, Johannes, van Nueten, Luc, Krams, Michael, Winkler, Angela, Pundt, Noreen, Nathan, Pradeep J., Rock, Philippa, Cormack, Francesca K., Weimar, Christian

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Biomarker candidates of neurodegeneration in Parkinson’s disease for the evaluation of disease-modifying therapeutics von Gerlach, Manfred, Maetzler, Walter, Broich, Karl, Hampel, Harald, Rems, Lucas, Reum, Torsten, Riederer, Peter, Stöffler, Albrecht, Streffer, Johannes, Berg, Daniela

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NRP-1 Receptor Expression Mismatch in Skin of Subjects with Experimental and Diabetic Small Fiber Neuropathy von Van Acker, Nathalie, Ragé, Michael, Vermeirsch, Hilde, Schrijvers, Dorien, Nuydens, Rony, Byttebier, Geert, Timmers, Maarten, De Schepper, Stefanie, Streffer, Johannes, Andries, Luc, Plaghki, Léon, Cras, Patrick, Meert, Theo

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Prerequisites to launch neuroprotective trials in Parkinson's disease: An industry perspective von Streffer, Johannes R., Grachev, Igor D., Fitzer-Attas, Cheryl, Gomez-Mancilla, Baltazar, Boroojerdi, Babak, Bronzova, Juliana, Ostrowitzki, Susanne, Victor, Stephen J., Fontoura, Paulo, Alexander, Robert

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ABCA1 modulates CSF cholesterol levels and influences the age at onset of Alzheimer’s disease von Wollmer, M.Axel, Streffer, Johannes R, Lütjohann, Dieter, Tsolaki, Magdalini, Iakovidou, Vassiliki, Hegi, Thomas, Pasch, Thomas, Jung, Hans H, Bergmann, Klaus von, Nitsch, Roger M, Hock, Christoph, Papassotiropoulos, Andreas

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The β-Secretase BACE1 in Alzheimer’s Disease von Hampel, Harald, Vassar, Robert, De Strooper, Bart, Hardy, John, Willem, Michael, Singh, Neeraj, Zhou, John, Yan, Riqiang, Vanmechelen, Eugeen, De Vos, Ann, Nisticò, Robert, Corbo, Massimo, Imbimbo, Bruno Pietro, Streffer, Johannes, Voytyuk, Iryna, Timmers, Maarten, Tahami Monfared, Amir Abbas, Irizarry, Michael, Albala, Bruce, Koyama, Akihiko, Watanabe, Naoto, Kimura, Teiji, Yarenis, Lisa, Lista, Simone, Kramer, Lynn, Vergallo, Andrea

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