Dual-Action Combination Therapy Enhances Angiogenesis while Reducing Tumor Growth and Spread von Wong, Ping-Pui, Demircioglu, Fevzi, Ghazaly, Essam, Alrawashdeh, Wasfi, Stratford, Michael R.L., Scudamore, Cheryl L., Cereser, Biancastella, Crnogorac-Jurcevic, Tatjana, McDonald, Stuart, Elia, George, Hagemann, Thorsten, Kocher, Hemant M., Hodivala-Dilke, Kairbaan M.

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Design, synthesis and evaluation of molecularly targeted hypoxia-activated prodrugs von O'Connor, Liam J, Cazares-Körner, Cindy, Saha, Jaideep, Evans, Charles N G, Stratford, Michael R L, Hammond, Ester M, Conway, Stuart J

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Mechanistic studies of the inactivation of tyrosinase by resorcinol von Stratford, Michael R.L., Ramsden, Christopher A., Riley, Patrick A.

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The influence of hydroquinone on tyrosinase kinetics von Stratford, Michael R.L., Ramsden, Christopher A., Riley, Patrick A.

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Radiosensitization In Vivo by Histone Deacetylase Inhibition with No Increase in Early Normal Tissue Radiation Toxicity von Groselj, Blaz, Ruan, Jia-Ling, Scott, Helen, Gorrill, Jessica, Nicholson, Judith, Kelly, Jacqueline, Anbalagan, Selvakumar, Thompson, James, Stratford, Michael R L, Jevons, Sarah J, Hammond, Ester M, Scudamore, Cheryl L, Kerr, Martin, Kiltie, Anne E

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Phase I Clinical and Pharmacokinetic Evaluation of the Vascular-Disrupting Agent OXi4503 in Patients with Advanced Solid Tumors von PATTERSON, Dan M, ZWEIFEL, Martin, CHAPLIN, Dai J, PADHANI, Anwar R, RUSTIN, Gordon J. S, MIDDLETON, Mark R, PRICE, Patricia M, FOLKES, Lisa K, STRATFORD, Michael R. L, ROSS, Phil, HALFORD, Sarah, PETERS, Jane, BALKISSOON, Jai

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The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia von Ashton, Thomas M., Fokas, Emmanouil, Kunz-Schughart, Leoni A., Folkes, Lisa K., Anbalagan, Selvakumar, Huether, Melanie, Kelly, Catherine J., Pirovano, Giacomo, Buffa, Francesca M., Hammond, Ester M., Stratford, Michael, Muschel, Ruth J., Higgins, Geoff S., McKenna, William Gillies

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Deoxycytidine kinase expression underpins response to gemcitabine in bladder cancer von Kerr, Martin, Scott, Helen E, Groselj, Blaz, Stratford, Michael R L, Karaszi, Katalin, Sharma, Naomi L, Kiltie, Anne E

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A phase 1 study to assess the safety, tolerability, and pharmacokinetics of CXD101 in patients with advanced cancer von Eyre, Toby A., Collins, Graham P., Gupta, Avinash, Coupe, Nicholas, Sheikh, Semira, Whittaker, John, Wang, Lai Mun, Campo, Leticia, Soilleux, Elizabeth, Tysoe, Finn, Cousins, Richard, La Thangue, Nick, Folkes, Lisa K., Stratford, Michael R. L., Kerr, David, Middleton, Mark R.

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A first-in-human phase I study to determine the maximum tolerated dose of the oral Src/ABL inhibitor AZD0424 von Woodcock, Victoria K, Clive, Sally, Wilson, Richard H, Coyle, Vicky M, Stratford, Michael R L, Folkes, Lisa K, Eastell, Richard, Barton, Claire, Jones, Paul, Kazmi-Stokes, Shamim, Turner, Helen, Halford, Sarah, Harris, Adrian L, Middleton, Mark R

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Oxidative Metabolism of Combretastatin A-1 Produces Quinone Intermediates with the Potential To Bind to Nucleophiles and To Enhance Oxidative Stress via Free Radicals von Folkes, Lisa K, Christlieb, Martin, Madej, Edyta, Stratford, Michael R. L, Wardman, Peter

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Validation of a method for the determination of the anticancer agent Combretastatin A1 phosphate (CA1P, OXi4503) in human plasma by HPLC with post-column photolysis and fluorescenc... von Stratford, Michael R.L., Folkes, Lisa K.

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Oxidative calcium release from catechol von Riley, Patrick A., Stratford, Michael R.L.

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A validated HPLC method with fluorescence detection for the glucuronides of Combretastatin A1 in human plasma, and studies on their cis–trans isomerisation von Stratford, Michael R.L., Folkes, Lisa K.

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Dual Inhibition of the PI3K/mTOR Pathway Increases Tumor Radiosensitivity by Normalizing Tumor Vasculature von FOKAS, Emmanouil, JAE HONG IM, MUSCHEL, Ruth J, HILL, Sally, YAMEEN, Sabira, STRATFORD, Michael, BEECH, John, HACKL, Wolfgang, MAIRA, Sauveur-Michel, BEMHARD, Eric J, GILLIES MCKENNA, W

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The influence of catechol structure on the suicide-inactivation of tyrosinase von Ramsden, Christopher A, Stratford, Michael R L, Riley, Patrick A

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Quantitative determination of the anticancer prodrug combretastatin A1 phosphate (OXi4503, CA1P), the active CA1 and its glucuronide metabolites in human urine and of CA1 in plasma... von Stratford, Michael R.L., Folkes, Lisa K.

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Phase I Clinical Trial of Weekly Combretastatin A4 Phosphate: Clinical and Pharmacokinetic Results von RUSTIN, Gordon J. S, GALBRAITH, Susan M, ANDERSON, Helen, STRATFORD, Michael, FOLKES, Lisa K, SENA, Luiza, GUMBRELL, Lindsey, PRICE, Patricia M

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Enhanced fluorescence detection of cis-combretastatins by post-column photolysis von Stratford, Michael R.L.

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ZD6126: A novel vascular-targeting agent that causes selective destruction of tumor vasculature von DAVIS, Peter D, DOUGHERTY, Graeme J, HILL, Sally A, BLAKEY, David C, GALBRAITH, Susan M, TOZER, Gillian M, HOLDER, Angela L, NAYLOR, Matthew A, NOLAN, John, STRATFORD, Michael R. L, CHAPLIN, David J

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