Site and strain-specific variation in gut microbiota profiles and metabolism in experimental mice von Friswell, Melissa K, Gika, Helen, Stratford, Ian J, Theodoridis, Georgios, Telfer, Brian, Wilson, Ian D, McBain, Andrew J

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Inhibition of monocarboxylate transporter-1 (MCT1) by AZD3965 enhances radiosensitivity by reducing lactate transport von Bola, Becky M, Chadwick, Amy L, Michopoulos, Filippos, Blount, Kathryn G, Telfer, Brian A, Williams, Kaye J, Smith, Paul D, Critchlow, Susan E, Stratford, Ian J

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The CD44‐Mediated Uptake of Hyaluronic Acid‐Based Carriers in Macrophages von Rios de la Rosa, Julio M., Tirella, Annalisa, Gennari, Arianna, Stratford, Ian J., Tirelli, Nicola

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Inhibition of PARP-1 by olaparib (AZD2281) increases the radiosensitivity of a lung tumor xenograft von Senra, Joana M, Telfer, Brian A, Cherry, Kim E, McCrudden, Cian M, Hirst, David G, O'Connor, Mark J, Wedge, Stephen R, Stratford, Ian J

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Hypoxia-Mediated Down-Regulation of Bid and Bax in Tumors Occurs via Hypoxia-Inducible Factor 1-Dependent and -Independent Mechanisms and Contributes to Drug Resistance von Erler, Janine T., Cawthorne, Christopher J., Williams, Kaye J., Koritzinsky, Marianne, Wouters, Bradley G., Wilson, Clare, Miller, Crispin, Demonacos, Costas, Stratford, Ian J., Dive, Caroline

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Targeting Hypoxia-Inducible Factor-1α in Pancreatic Cancer: siRNA Delivery Using Hyaluronic Acid-Displaying Nanoparticles von Spadea, Alice, Tirella, Annalisa, Rios de la Rosa, Julio Manuel, Lallana, Enrique, Mehibel, Manal, Telfer, Brian, Tirelli, Nicola, Lawrence, Margaret Jayne, Williams, Kaye J, Stratford, Ian J, Ashford, Marianne

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Monocarboxylate Transporter 1 (MCT1) is an independent prognostic biomarker in endometrial cancer von Latif, Ayşe, Chadwick, Amy L, Kitson, Sarah J, Gregson, Hannah J, Sivalingam, Vanitha N, Bolton, James, McVey, Rhona J, Roberts, Stephen A, Marshall, Kay M, Williams, Kaye J, Stratford, Ian J, Crosbie, Emma J

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Acquired resistance to fractionated radiotherapy can be overcome by concurrent PD-L1 blockade von Dovedi, Simon J, Adlard, Amy L, Lipowska-Bhalla, Grazyna, McKenna, Conor, Jones, Sherrie, Cheadle, Eleanor J, Stratford, Ian J, Poon, Edmund, Morrow, Michelle, Stewart, Ross, Jones, Hazel, Wilkinson, Robert W, Honeychurch, Jamie, Illidge, Tim M

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Synthesis and Biological Evaluation of Coumarin-Based Inhibitors of NAD(P)H: Quinone Oxidoreductase-1 (NQO1) von Nolan, Karen A, Doncaster, Jeremy R, Dunstan, Mark S, Scott, Katherine A, Frenkel, A. David, Siegel, David, Ross, David, Barnes, John, Levy, Colin, Leys, David, Whitehead, Roger C, Stratford, Ian J, Bryce, Richard A

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Akt inhibition improves long‐term tumour control following radiotherapy by altering the microenvironment von Searle, Emma J, Telfer, Brian A, Mukherjee, Debayan, Forster, Duncan M, Davies, Barry R, Williams, Kaye J, Stratford, Ian J, Illidge, Tim M

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iNOS as a therapeutic target for treatment of human tumors von Fitzpatrick, Brian, Mehibel, Manal, Cowen, Rachel L., Stratford, Ian J.

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Evaluating the Efficiency of Hyaluronic Acid for Tumor Targeting via CD44 von Spadea, Alice, Rios de la Rosa, Julio Manuel, Tirella, Annalisa, Ashford, Marianne B, Williams, Kaye J, Stratford, Ian J, Tirelli, Nicola, Mehibel, Manal

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Expression of vascular endothelial growth factor (VEGF) in locally invasive prostate cancer is prognostic for radiotherapy outcome von Green, Melanie M.L., Ph.D, Hiley, Crispin T., M.B.Ch.B, Shanks, Jonathan H., M.R.C.Path, Bottomley, Ian C., B.A.Hons, West, Catharine M.L., Ph.D, Cowan, Richard A., F.R.C.R, Stratford, Ian J., Ph.D

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Chitosan/Hyaluronic Acid Nanoparticles: Rational Design Revisited for RNA Delivery von Lallana, Enrique, Rios de la Rosa, Julio M, Tirella, Annalisa, Pelliccia, Maria, Gennari, Arianna, Stratford, Ian J, Puri, Sanyogitta, Ashford, Marianne, Tirelli, Nicola

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Reversing Hypoxic Cell Chemoresistance in Vitro Using Genetic and Small Molecule Approaches Targeting Hypoxia Inducible Factor-1 von Brown, Louisa M, Cowen, Rachel L, Debray, Camille, Eustace, Amanda, Erler, Janine T, Sheppard, Freda C D, Parker, Catriona A, Stratford, Ian J, Williams, Kaye J

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GLUT‐1 and CAIX as intrinsic markers of hypoxia in carcinoma of the cervix: Relationship to pimonidazole binding von Airley, Rachel E., Loncaster, Juliette, Raleigh, James A., Harris, Adrian L., Davidson, Susan E., Hunter, Robert D., West, Catharine M.L., Stratford, Ian J.

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The Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase Kinase 1/2 Inhibitor AZD6244 (ARRY-142886) Enhances the Radiation Responsiveness of Lung and Colorectal Tumor Xe... von Shannon, Aoife M, Telfer, Brian A, Smith, Paul D, Babur, Muhammed, Logie, Armelle, Wilkinson, Robert W, Debray, Camille, Stratford, Ian J, Williams, Kaye J, Wedge, Stephen R

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Dissecting the Role of Multiple Reductases in Bioactivation and Cytotoxicity of the Antitumor Agent 2,5-Diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone (RH1) von Yan, Chao, Kepa, Jadwiga K, Siegel, David, Stratford, Ian J, Ross, David

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Discovery of Potent Benzothiazole Inhibitors of Oxidoreductase NQO2, a Target for Inflammation and Cancer von Belgath, Asma A., Emam, Aya M., Taujanskas, Joshua, Bryce, Richard A., Freeman, Sally, Stratford, Ian J.

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In vivo activation of the hypoxia-targeted cytotoxin AQ4N in human tumor xenografts von Williams, Kaye J, Albertella, Mark R, Fitzpatrick, Brian, Loadman, Paul M, Shnyder, Steven D, Chinje, Edwin C, Telfer, Brian A, Dunk, Chris R, Harris, Peter A, Stratford, Ian J

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