Discovery of Novel 2-Aminobenzamide Inhibitors of Heat Shock Protein 90 as Potent, Selective and Orally Active Antitumor Agents von Huang, Kenneth H, Veal, James M, Fadden, R. Patrick, Rice, John W, Eaves, Jeron, Strachan, Jon-Paul, Barabasz, Amy F, Foley, Briana E, Barta, Thomas E, Ma, Wei, Silinski, Melanie A, Hu, Mei, Partridge, Jeffrey M, Scott, Anisa, DuBois, Laura G, Freed, Tiffany, Steed, Paul M, Ommen, Andy J, Smith, Emilie D, Hughes, Philip F, Woodward, Angela R, Hanson, Gunnar J, McCall, W. Stephen, Markworth, Christopher J, Hinkley, Lindsay, Jenks, Matthew, Geng, Lifeng, Lewis, Meredith, Otto, James, Pronk, Bert, Verleysen, Katleen, Hall, Steven E

Volltext

Effects of Orbital Ordering on Electronic Communication in Multiporphyrin Arrays von Strachan, Jon-Paul, Gentemann, Steve, Seth, Jyoti, Kalsbeck, William A., Lindsey, Jonathan S., Holten, Dewey, Bocian, David F.

Volltext

α4β2 nicotinic receptors play a role in the nAChR-mediated decline in l-dopa-induced dyskinesias in parkinsonian rats von Quik, Maryka, Campos, Carla, Bordia, Tanuja, Strachan, Jon-Paul, Zhang, Jenny, McIntosh, J. Michael, Letchworth, Sharon, Jordan, Kristen

Volltext

Rational Synthesis of Meso-Substituted Chlorin Building Blocks von Strachan, Jon-Paul, O'Shea, Donal F, Balasubramanian, Thiagarajan, Lindsey, Jonathan S

Volltext

Synthesis of 2-(Pyridin-3-yl)-1-azabicyclo[3.2.2]nonane, 2-(Pyridin-3-yl)-1-azabicyclo[2.2.2]octane, and 2-(Pyridin-3-yl)-1-azabicyclo[3.2.1]octane, a Class of Potent Nicotinic Ace... von Bhatti, Balwinder S, Strachan, Jon-Paul, Breining, Scott R, Miller, Craig H, Tahiri, Persida, Crooks, Peter A, Deo, Niranjan, Day, Cynthia S, Caldwell, William S

Volltext

Computational studies of novel carbonyl-containing diazabicyclic ligands interacting with α4β2 nicotinic acetylcholine receptor (nAChR) reveal alternative binding modes von Kombo, David C., Mazurov, Anatoly A., Strachan, Jon-Paul, Bencherif, Merouane

Volltext

Identification and pharmacological characterization of 3,6-diazabicyclo[3.1.1]heptane-3-carboxamides as novel ligands for the α4β2 and α6/α3β2β3 nicotinic acetylcholine receptors (... von Strachan, Jon-Paul, Kombo, David C., Mazurov, Anatoly, Heemstra, Ronald, Bhatti, Balwinder S., Akireddy, Rao, Murthy, Srinivasa, Miao, Lan, Jett, John E., Speake, Jason, Bencherif, Merouane

Volltext

Discovery of 3‑(5-Chloro-2-furoyl)-3,7-diazabicyclo[3.3.0]octane (TC-6683, AZD1446), a Novel Highly Selective α4β2 Nicotinic Acetylcholine Receptor Agonist for the Treatment of Cog... von Mazurov, Anatoly A, Miao, Lan, Bhatti, Balwinder S, Strachan, Jon-Paul, Akireddy, Srinivasa, Murthy, Srinivasa, Kombo, David, Xiao, Yun-de, Hammond, Philip, Zhang, Jenny, Hauser, Terry A, Jordan, Kristen G, Miller, Craig H, Speake, Jason D, Gatto, Gregory J, Yohannes, Daniel

Volltext

Diazaspirocyclic compounds as selective ligands for the α4β2 nicotinic acetylcholine receptor von Strachan, Jon-Paul, Farias, Jarrett J., Zhang, Jenny, Caldwell, William S., Bhatti, Balwinder S.

Volltext

Synthesis and Characterization of Tetrachlorodiarylethyne-Linked Porphyrin Dimers. Effects of Linker Architecture on Intradimer Electronic Communication von Strachan, Jon-Paul, Gentemann, Steve, Seth, Jyoti, Kalsbeck, William A, Lindsey, Jonathan S, Holten, Dewey, Bocian, David F

Volltext

Pharmacological properties and predicted binding mode of arylmethylene quinuclidine-like derivatives at the α3β4 nicotinic acetylcholine receptor (nAChR) von Kombo, David C., Hauser, Terry A., Grinevich, Vladimir P., Melvin, Matthew S., Strachan, Jon-Paul, Sidach, Serguei S., Chewning, Joseph, Fedorov, Nikolai, Tallapragada, Kartik, Breining, Scott R., Miller, Craig H.

Volltext

Synthesis of Bicyclic Tertiary α-Amino Acids von Strachan, Jon-Paul, Whitaker, Regina C, Miller, Craig H, Bhatti, Balwinder S

Volltext

Trans-Substituted porphyrin building blocks bearing iodo and ethynyl groups for applications in bioorganic and materials chemistry von Ravikanth, M., Strachan, Jon-Paul, Li, Feirong, Lindsey, Jonathan S.

Volltext

alpha 4 beta 2 nicotinic receptors play a role in the nAChR-mediated decline in l-dopa-induced dyskinesias in parkinsonian rats von Quik, Maryka, Campos, Carla, Bordia, Tanuja, Strachan, Jon-Paul, Zhang, Jenny, McIntosh, JMichael, Letchworth, Sharon, Jordan, Kristen

Volltext

Computational studies of novel carbonyl-containing diazabicyclic ligands interacting with I-4I22 nicotinic acetylcholine receptor (nAChR) reveal alternative binding modes von Kombo, David, Mazurov, Anatoly, Strachan, Jon-Paul, Bencherif, Merouane

Volltext

The preparation of some 1,7b-disubstituted cyclopropa[c]isoquinolines via nitrile ylide cyclisations and their rearrangement to 2-benzazepines and 4-alkenyl-1,4-dihydroisoquinoline... von Strachan, Jon-Paul, Sharp, John T., Parsons, Simon

Volltext

Rational Synthesis of β-Substituted Chlorin Building Blocks von Balasubramanian, Thiagarajan, Strachan, Jon-Paul, Boyle, Paul D, Lindsey, Jonathan S

Volltext

ChemInform Abstract: Rational Synthesis of meso-Substituted Chlorin Building Blocks von Strachan, Jon-Paul, O'Shea, Donal F., Balasubramanian, Thiagarajan, Lindsey, Jonathan S.

Volltext

ChemInform Abstract: A Route to 1,4-Prop[2]enoisoquinolines via the Cyclization of Triene-Conjugated Nitrile Ylides von Strachan, Jon-Paul, Sharp, John T., Crawshaw, Melanie J.

Volltext

Rational Synthesis of Meso-Substituted Chlorin Building Blocks von Strachan, Jon-Paul, O'Shea, Donal F, Balasubramanian, Thiagarajan, Lindsey, Jonathan S

Volltext