Impaired Inflammatory and Pain Responses in Mice Lacking an Inducible Prostaglandin E Synthase von Trebino, Catherine E., Stock, Jeffrey L., Gibbons, Colleen P., Naiman, Brian M., Wachtmann, Timothy S., Umland, John P., Pandher, Karamjeet, Lapointe, Jean-Martin, Saha, Sipra, Roach, Marsha L., Carter, Demetrius, Thomas, Nathalie A., Durtschi, Becky A., McNeish, John D., Hambor, John E., Jakobsson, Per-Johan, Carty, Thomas J., Perez, Jose R., Audoly, Laurent P.

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Genetic deletion of the striatum-enriched phosphodiesterase PDE10A: Evidence for altered striatal function von Siuciak, Judith A., McCarthy, Sheryl A., Chapin, Douglas S., Fujiwara, Remie A., James, Larry C., Williams, Robert D., Stock, Jeffrey L., McNeish, John D., Strick, Christine A., Menniti, Frank S., Schmidt, Christopher J.

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Targeted Disruption of Murine Organic Anion-Transporting Polypeptide 1b2 (oatp1b2/Slco1b2) Significantly Alters Disposition of Prototypical Drug Substrates Pravastatin and Rifampin von Zaher, Hani, Meyer zu Schwabedissen, Henriette E, Tirona, Rommel G, Cox, Melissa L, Obert, Leslie A, Agrawal, Nidhi, Palandra, Joe, Stock, Jeffrey L, Kim, Richard B, Ware, Joseph A

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Targeted Disruption of the Osteoblast/Osteocyte Factor 45 Gene (OF45) Results in Increased Bone Formation and Bone Mass von Gowen, Lori C., Petersen, Donna N., Mansolf, Amy L., Qi, Hong, Stock, Jeffrey L., Tkalcevic, George T., Simmons, Hollis A., Crawford, David T., Chidsey-Frink, Kristen L., Ke, Hua Zhu, McNeish, John D., Brown, Thomas A.

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Kinase Suppressor of Ras (KSR) Is a Scaffold Which Facilitates Mitogen-Activated Protein Kinase Activation In Vivo von Nguyen, AnhCo, Burack, W. Richard, Stock, Jeffrey L., Kortum, Robert, Chaika, Oleg V., Afkarian, Maryam, Muller, William J., Murphy, Kenneth M., Morrison, Deborah K., Lewis, Robert E., McNeish, John, Shaw, Andrey S.

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Genetically Engineered Mouse Models in Drug Discovery Research von Sacca, Rosalba, Engle, Sandra J., Qin, Wenning, Stock, Jeffrey L., McNeish, John D.

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Receptors and Signaling Mechanisms Required for Prostaglandin E2-Mediated Regulation of Mast Cell Degranulation and IL-6 Production von Nguyen, MyTrang, Solle, Michael, Audoly, Laurent P, Tilley, Stephen L, Stock, Jeffrey L, McNeish, John D, Coffman, Thomas M, Dombrowicz, David, Koller, Beverly H

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Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta von Garofalo, Robert S, Orena, Stephen J, Rafidi, Kristina, Torchia, Anthony J, Stock, Jeffrey L, Hildebrandt, Audrey L, Coskran, Timothy, Black, Shawn C, Brees, Dominique J, Wicks, Joan R, McNeish, John D, Coleman, Kevin G

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Identification of specific EP receptors responsible for the hemodynamic effects of PGE2 von Audoly, Laurent P, Tilley, Stephen L, Goulet, Jennifer, Key, Mikelle, Nguyen, Mytrang, Stock, Jeffrey L, McNeish, John D, Koller, Beverly H, Coffman, Thomas M

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Glycemic Control in Mice with Targeted Disruption of the Glucagon Receptor Gene von Parker, Janice C., Andrews, Kim M., Allen, Melanie R., Stock, Jeffrey L., McNeish, John D.

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The prostaglandin E2 EP1 receptor mediates pain perception and regulates blood pressure von Stock, J L, Shinjo, K, Burkhardt, J, Roach, M, Taniguchi, K, Ishikawa, T, Kim, H S, Flannery, P J, Coffman, T M, McNeish, J D, Audoly, L P

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Engineering Autoactivating Forms of Matrix Metalloproteinase-9 and Expression of the Active Enzyme in Cultured Cells and Transgenic Mouse Brain von Fisher, Katherine E, Fei, Qing, Laird, Ellen R, Stock, Jeffrey L, Allen, Melanie R, Sahagan, Barbara G, Strick, Christine A

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Defects in embryonic development of EGLN1/PHD2 knockdown transgenic mice are associated with induction of Igfbp in the placenta von Ozolinš, Terence R.S., Fisher, Timothy S., Nadeau, Diane M., Stock, Jeffrey L., Klein, Anne S., Milici, Anthony J., Morton, Daniel, Wilhelms, Margaret B., Brissette, William H., Li, Baiyong

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E-Prostanoid-3 Receptors Mediate the Proinflammatory Actions of Prostaglandin E2 in Acute Cutaneous Inflammation von Goulet, Jennifer L, Pace, Amy J, Key, Mikelle L, Byrum, Robert S, Nguyen, MyTrang, Tilley, Stephen L, Morham, Scott G, Langenbach, Robert, Stock, Jeffrey L, McNeish, John D, Smithies, Oliver, Coffman, Thomas M, Koller, Beverly H

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Analysis of the role of the HIF hydroxylase family members in erythropoiesis von Fisher, Timothy S., Lira, Paul D., Stock, Jeffrey L., Perregaux, David G., Brissette, William H., Ozolinš, Terence R.S., Li, Baiyong

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Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta von Garofalo, R S, Orena, S J, Rafidi, K, Torchia, A J, Stock, J L, Hildebrandt, AL, Coskran, T, Black, S C, Brees, D J, Wicks, J R, McNeish, J D, Coleman, K G

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Collagen-induced arthritis is reduced in 5-lipoxygenase-activating protein-deficient mice von Griffiths, R J, Smith, M A, Roach, M L, Stock, J L, Stam, E J, Milici, A J, Scampoli, D N, Eskra, J D, Byrum, R S, Koller, B H, McNeish, J D

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Gsh‐1: A novel murine homeobox gene expressed in the central nervous system von Valerius, M. Todd, Li, Hung, Stock, Jeffrey L., Weinstein, Michael, Kaur, Satbir, Singh, Gurparkash, Potter, S. Steven

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A New Embryonic Stem Cell Line from DBA/1lacJ Mice Allows Genetic Modification in a Murine Model of Human Inflammation von Roach, Marsha L., Stock, Jeffrey L., Byrum, Robert, Koller, Beverly H., McNeish, John D.

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Abstract 2336: Assessment of mechanisms of action (MOAs) of the Fc-engineered integrin α5β1 targeting antibody PF-04605412 in human integrin α5 knock-in mice von Zhang, Lianglin, Stock, Jeffrey L., Elliott, Mark W., Chen, Enhong, Nguyen, Thao, Wong, Anthony, Davis, Craig B., Christensen, James G.

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