BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design von Farnaby, William, Koegl, Manfred, Roy, Michael J., Whitworth, Claire, Diers, Emelyne, Trainor, Nicole, Zollman, David, Steurer, Steffen, Karolyi-Oezguer, Jale, Riedmueller, Carina, Gmaschitz, Teresa, Wachter, Johannes, Dank, Christian, Galant, Michael, Sharps, Bernadette, Rumpel, Klaus, Traxler, Elisabeth, Gerstberger, Thomas, Schnitzer, Renate, Petermann, Oliver, Greb, Peter, Weinstabl, Harald, Bader, Gerd, Zoephel, Andreas, Weiss-Puxbaum, Alexander, Ehrenhöfer-Wölfer, Katharina, Wöhrle, Simon, Boehmelt, Guido, Rinnenthal, Joerg, Arnhof, Heribert, Wiechens, Nicola, Wu, Meng-Ying, Owen-Hughes, Tom, Ettmayer, Peter, Pearson, Mark, McConnell, Darryl B., Ciulli, Alessio

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Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor von Martin, Laetitia J, Koegl, Manfred, Bader, Gerd, Cockcroft, Xiao-Ling, Fedorov, Oleg, Fiegen, Dennis, Gerstberger, Thomas, Hofmann, Marco H, Hohmann, Anja F, Kessler, Dirk, Knapp, Stefan, Knesl, Petr, Kornigg, Stefan, Müller, Susanne, Nar, Herbert, Rogers, Catherine, Rumpel, Klaus, Schaaf, Otmar, Steurer, Steffen, Tallant, Cynthia, Vakoc, Christopher R, Zeeb, Markus, Zoephel, Andreas, Pearson, Mark, Boehmelt, Guido, McConnell, Darryl

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Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6 von Kerres, Nina, Steurer, Steffen, Schlager, Stefanie, Bader, Gerd, Berger, Helmut, Caligiuri, Maureen, Dank, Christian, Engen, John R., Ettmayer, Peter, Fischerauer, Bernhard, Flotzinger, Gerlinde, Gerlach, Daniel, Gerstberger, Thomas, Gmaschitz, Teresa, Greb, Peter, Han, Bingsong, Heyes, Elizabeth, Iacob, Roxana E., Kessler, Dirk, Kölle, Heike, Lamarre, Lyne, Lancia, David R., Lucas, Simon, Mayer, Moriz, Mayr, Katharina, Mischerikow, Nikolai, Mück, Katja, Peinsipp, Christoph, Petermann, Oliver, Reiser, Ulrich, Rudolph, Dorothea, Rumpel, Klaus, Salomon, Carina, Scharn, Dirk, Schnitzer, Renate, Schrenk, Andreas, Schweifer, Norbert, Thompson, Diane, Traxler, Elisabeth, Varecka, Roland, Voss, Tilman, Weiss-Puxbaum, Alexander, Winkler, Sandra, Zheng, Xiaozhang, Zoephel, Andreas, Kraut, Norbert, McConnell, Darryl, Pearson, Mark, Koegl, Manfred

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Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions von Popow, Johannes, Arnhof, Heribert, Bader, Gerd, Berger, Helmut, Ciulli, Alessio, Covini, David, Dank, Christian, Gmaschitz, Teresa, Greb, Peter, Karolyi-Özguer, Jale, Koegl, Manfred, McConnell, Darryl B, Pearson, Mark, Rieger, Maria, Rinnenthal, Joerg, Roessler, Vanessa, Schrenk, Andreas, Spina, Markus, Steurer, Steffen, Trainor, Nicole, Traxler, Elisabeth, Wieshofer, Corinna, Zoephel, Andreas, Ettmayer, Peter

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Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition von Hohmann, Anja F, Martin, Laetitia J, Minder, Jessica L, Roe, Jae-Seok, Shi, Junwei, Steurer, Steffen, Bader, Gerd, McConnell, Darryl, Pearson, Mark, Gerstberger, Thomas, Gottschamel, Teresa, Thompson, Diane, Suzuki, Yutaka, Koegl, Manfred, Vakoc, Christopher R

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A Novel RAF Kinase Inhibitor with DFG-Out-Binding Mode: High Efficacy in BRAF-Mutant Tumor Xenograft Models in the Absence of Normal Tissue Hyperproliferation von Waizenegger, Irene C, Baum, Anke, Steurer, Steffen, Stadtmüller, Heinz, Bader, Gerd, Schaaf, Otmar, Garin-Chesa, Pilar, Schlattl, Andreas, Schweifer, Norbert, Haslinger, Christian, Colbatzky, Florian, Mousa, Sien, Kalkuhl, Arno, Kraut, Norbert, Adolf, Günther R

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Abstract 3849: Structure-based PROTAC design demonstrates BAF complex ATPase vulnerabilities in cancer von Koegl, Manfred, Farnaby, William, Whitworth, Claire, Roy, Michael, Diers, Emelyne, Trainor, Nicole, Steurer, Steffen, Riedmueller, Carina, Gmaschitz, Teresa, Wachter, Johannes, Dank, Christian, Gallant, Michael, Sharps, Bernadette, Rumpel, Klaus, Traxler, Elisabeth, Lorenz, Romario, Petermann, Oliver, Greb, Peter, Weinstabl, Harald, Bader, Gerd, Zoephel, Andreas, Weiss-Puxbaum, Alexander, Rinnenthal, Joerg, Arnnhof, Heribert, Wiechens, Nicola, Wu, Meng-Ying, Owen-Hughes, Tom, Ettmayer, Peter, Pearson, Mark, McConnell, Darryl B., Ciulli, Alessio

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Abstract 3354: Chemically induced degradation of the transcription factor BCL6 von Kerres, Nina, Steurer, Steffen, Schlager, Stefanie, Bader, Gerd, Caligiuri, Maureen, Dank, Christian, Engen, John R., Ettmayer, Peter, Gerlach, Daniel, Gerstberger, Thomas, Han, Bingsong, Iacob, Roxana E., Kessler, Dirk, Lancia, David R., Moriz, Mayer, Mischerikow, Nikolai, Rumpel, Klaus, Schnitzer, Renate, Voss, Tilman, Zheng, Xiaozhang, Zoephel, Andreas, Kraut, Norbert, McConnell, Darryl, Pearson, Mark, Koegl, Manfred

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Publisher Correction: BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design von Farnaby, William, Koegl, Manfred, Roy, Michael J., Whitworth, Claire, Diers, Emelyne, Trainor, Nicole, Zollman, David, Steurer, Steffen, Karolyi-Oezguer, Jale, Riedmueller, Carina, Gmaschitz, Teresa, Wachter, Johannes, Dank, Christian, Galant, Michael, Sharps, Bernadette, Rumpel, Klaus, Traxler, Elisabeth, Gerstberger, Thomas, Schnitzer, Renate, Petermann, Oliver, Greb, Peter, Weinstabl, Harald, Bader, Gerd, Zoephel, Andreas, Weiss-Puxbaum, Alexander, Ehrenhöfer-Wölfer, Katharina, Wöhrle, Simon, Boehmelt, Guido, Rinnenthal, Joerg, Arnhof, Heribert, Wiechens, Nicola, Wu, Meng-Ying, Owen-Hughes, Tom, Ettmayer, Peter, Pearson, Mark, McConnell, Darryl B., Ciulli, Alessio

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Abstract LB-206: A bromodomain-swap allele demonstrates that on-target chemical inhibition of BRD9 limits the proliferation of acute myeloid leukemia cells von Hohmann, Anja F., Martin, Laetitia J., Minder, Jessica, Roe, Jae-Seok, Shi, Junwei, Steurer, Steffen, Bader, Gerd, McConnell, Darryl, Pearson, Mark, Gerstberger, Thomas, Gottschamel, Teresa, Thompson, Diane, Suzuki, Yutaka, Koegl, Manfred, Vakoc, Christopher

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Abstract 1525: Chemically induced degradation of the oncogenic transcription factor BCL6 von Kerres, Nina, Steurer, Steffen, Schlager, Stefanie, Bader, Gerd, Berger, Helmut, Blake, Sophia, Caligiuri, Maureen, Engen, John, Ettmayer, Peter, Gerstberger, Thomas, Gerlach, Daniel, Jacob, Roxana, Lucas, Simon, Mayer, Moriz, Nikolai, Mischerikow, Klaus, Rumpel, Dirk, Scharn, Renate, Schnitzer, Voss, Tilman, Andreas, Zoephel, Kraut, Norbert, McConnell, Darryl, Mark, Pearson, Koegl, Manfred

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Abstract 2344: Modeling 1st- and 2nd-line therapy of BRAF mutant melanoma using a novel BRAF inhibitor with DFG-out binding mode von Waizenegger, Irene C., Baum, Anke, Stadtmüller, Heinz, Steurer, Steffen, Bader, Gerd, Garin-Chesa, Pilar, Schweifer, Norbert, Bernthaler, Andreas, Haslinger, Christian, Schaaf, Otmar, Mousa, Sien, Colbatzky, Florian, Adolf, Günther R.

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Synthesis of Highly Functionalized Amino Acid and Hydroxy Acid Derivatives from γ-Aminoalkyl-Substituted α-Methylene-γ-butyrolactones von Steurer, Steffen, Podlech, Joachim

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Aminoalkyl-Substituted α-Methylene-γ-butyrolactones from α-Amino Acids Using an Indium-Mediated Barbier Allyl Addition von Steurer, Steffen, Podlech, Joachim

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Indium-Catalyzed Barbier-Reactions of Amino Aldehydes von Steurer, Steffen, Podlech, Joachim

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A Chiral, Oxidatively Cleavable Auxiliary in β-Lactam Synthesis - Double Diastereocontrol with p-Methoxyphenethyl-Substituted Imines von Podlech, Joachim, Steurer, Steffen

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Indium-Induced Addition of Bromomethylacrylates to Phthaloyl-Protected Amino Aldehydes von Steurer, Steffen, Podlech, Joachim

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NEW PYRIDINONES AND ISOQUINOLINONES AS INHIBITORS OF THE BROMODOMAIN BRD9 von MARTIN, Laetitia, COCKCROFT, Xiao-Ling, STEURER, Steffen

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Pyridinones and isoquinolinones as inhibitors of the bromodomain BRD9 von Martin, Laetitia, Steurer, Steffen, Cockcroft, Xiao-Ling

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NEW TRIAZOLYLPHENYL SULFONAMIDES AS SERINE/THREONINE KINASE INHIBITORS von STEURER, STEFFEN

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