Inhibition of autotransporter biogenesis by small molecules von Steenhuis, Maurice, Abdallah, Abdallah M., de Munnik, Sabrina M., Kuhne, Sebastiaan, Sterk, Geert‐Jan, van den Berg van Saparoea, Bart, Westerhausen, Sibel, Wagner, Samuel, van der Wel, Nicole N., Wijtmans, Maikel, van Ulsen, Peter, Jong, Wouter S. P., Luirink, Joen

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Identification of Phenylphthalazinones as a New Class of Leishmania infantum Inhibitors von Sijm, Maarten, Heuvel, Erik, Matheeussen, An, Caljon, Guy, Maes, Louis, Sterk, Geert‐Jan, Esch, Iwan J. P., Leurs, Rob

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Structural Optimization of BIPPO Analogs as Potent Antimalarials von Zheng, Yang, Matheeussen, An, Maes, Louis, Caljon, Guy, Sterk, Geert Jan, Leurs, Rob

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Exploring the interaction of N-(benzothiazol-2-yl)pyrrolamide DNA gyrase inhibitors with the GyrB ATP-binding site lipophilic floor: A medicinal chemistry and QTAIM study von Zidar, Nace, Emanuel Cotman, Andrej, Sinnige, Wessel, Benek, Ondrej, Barančokova, Michaela, Zega, Anamarija, Peterlin Mašič, Lucija, Tomašič, Tihomir, Ilaš, Janez, Henderson, Sara R., Mundy, Julia E.A., Maxwell, Anthony, Stevenson, Clare E.M., Lawson, David M., Jan Sterk, Geert, Tosso, Rodrigo, Gutierrez, Lucas, Enriz, Ricardo D., Kikelj, Danijel

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Lead Optimization of Phthalazinone Phosphodiesterase Inhibitors as Novel Antitrypanosomal Compounds von Salado, Irene G, Singh, Abhimanyu K, Moreno-Cinos, Carlos, Sakaine, Guna, Siderius, Marco, Van der Veken, Pieter, Matheeussen, An, van der Meer, Tiffany, Sadek, Payman, Gul, Sheraz, Maes, Louis, Sterk, Geert-Jan, Leurs, Rob, Brown, David, Augustyns, Koen

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The single cyclic nucleotide-specific phosphodiesterase of the intestinal parasite Giardia lamblia represents a potential drug target von Kunz, Stefan, Balmer, Vreni, Sterk, Geert Jan, Pollastri, Michael P, Leurs, Rob, Müller, Norbert, Hemphill, Andrew, Spycher, Cornelia

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Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors von de Heuvel, Erik, Singh, Abhimanyu K., Edink, Ewald, van der Meer, Tiffany, van der Woude, Melanie, Sadek, Payman, Krell-Jørgensen, Mikkel P., van den Bergh, Toine, Veerman, Johan, Caljon, Guy, Kalejaiye, Titilola D., Wijtmans, Maikel, Maes, Louis, de Koning, Harry P., Jan Sterk, Geert, Siderius, Marco, de Esch, Iwan J.P., Brown, David G., Leurs, Rob

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To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A? von Zheng, Yang, Schroeder, Susanne, Kanev, Georgi K, Botros, Sanaa S, William, Samia, Sabra, Abdel-Nasser A, Maes, Louis, Caljon, Guy, Gil, Carmen, Martinez, Ana, Salado, Irene G, Augustyns, Koen, Edink, Ewald, Sijm, Maarten, de Heuvel, Erik, de Esch, Iwan J P, van der Meer, Tiffany, Siderius, Marco, Sterk, Geert Jan, Brown, David, Leurs, Rob

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3-nitroimidazo[1,2-b]pyridazine as a novel scaffold for antiparasitics with sub-nanomolar anti-Giardia lamblia activity von Zheng, Yang, Müller, Joachim, Kunz, Stefan, Siderius, Marco, Maes, Louis, Caljon, Guy, Müller, Norbert, Hemphill, Andrew, Sterk, Geert Jan, Leurs, Rob

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Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages von Munday, Jane C, Kunz, Stefan, Kalejaiye, Titilola D, Siderius, Marco, Schroeder, Susanne, Paape, Daniel, Alghamdi, Ali H, Abbasi, Zainab, Huang, Sheng Xiang, Donachie, Anne-Marie, William, Samia, Sabra, Abdel Nasser, Sterk, Geert Jan, Botros, Sanaa S, Brown, David G, Hoffman, Charles S, Leurs, Rob, de Koning, Harry P

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Structure Activity Relationship of N -Substituted Phenyldihydropyrazolones Against Trypanosoma cruzi Amastigotes von Sijm, Maarten, Maes, Louis, de Esch, Iwan J P, Caljon, Guy, Sterk, Geert Jan, Leurs, Rob

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Adhesion of Crithidia fasciculata promotes a rapid change in developmental fate driven by cAMP signaling von Denecke, Shane, Malfara, Madeline F, Hodges, Kelly R, Holmes, Nikki A, Williams, Andre R, Gallagher-Teske, Julia H, Pascarella, Julia M, Daniels, Abigail M, Sterk, Geert Jan, Leurs, Rob, Ruthel, Gordon, Hoang, Rachel, Povelones, Megan L, Povelones, Michael

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Discovery of Diaryl Ether Substituted Tetrahydrophthalazinones as TbrPDEB1 Inhibitors Following Structure-Based Virtual Screening von de Heuvel, Erik, Kooistra, Albert J, Edink, Ewald, van Klaveren, Sjors, Stuijt, Jeffrey, van der Meer, Tiffany, Sadek, Payman, Mabille, Dorien, Caljon, Guy, Maes, Louis, Siderius, Marco, de Esch, Iwan J P, Sterk, Geert Jan, Leurs, Rob

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Lead Optimization of the 5‑Phenylpyrazolopyrimidinone NPD-2975 toward Compounds with Improved Antitrypanosomal Efficacy von Zheng, Yang, van den Kerkhof, Magali, Ibrahim, Mohamed, De Esch, Iwan J. P., Maes, Louis, Sterk, Geert Jan, Caljon, Guy, Leurs, Rob

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Discovery of 5‑Phenylpyrazolopyrimidinone Analogs as Potent Antitrypanosomal Agents with In Vivo Efficacy von Zheng, Yang, van den Kerkhof, Magali, van der Meer, Tiffany, Gul, Sheraz, Kuzikov, Maria, Ellinger, Bernhard, de Esch, Iwan J. P., Siderius, Marco, Matheeussen, An, Maes, Louis, Sterk, Geert Jan, Caljon, Guy, Leurs, Rob

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Pharmacological Validation of Trypanosoma brucei Phosphodiesterases as Novel Drug Targets von de Koning, Harry P., Gould, Matthew K., Sterk, Geert Jan, Tenor, Hermann, Kunz, Stefan, Luginbuehl, Edith, Seebeck, Thomas

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Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa von Cotman, Andrej Emanuel, Durcik, Martina, Benedetto Tiz, Davide, Fulgheri, Federica, Secci, Daniela, Sterle, Maša, Možina, Štefan, Skok, Žiga, Zidar, Nace, Zega, Anamarija, Ilaš, Janez, Peterlin Mašič, Lucija, Tomašič, Tihomir, Hughes, Diarmaid, Huseby, Douglas L., Cao, Sha, Garoff, Linnéa, Berruga Fernández, Talía, Giachou, Paraskevi, Crone, Lisa, Simoff, Ivailo, Svensson, Richard, Birnir, Bryndis, Korol, Sergiy V., Jin, Zhe, Vicente, Francisca, Ramos, Maria C., de la Cruz, Mercedes, Glinghammar, Björn, Lenhammar, Lena, Henderson, Sara R., Mundy, Julia E. A., Maxwell, Anthony, Stevenson, Clare E. M., Lawson, David M., Janssen, Guido V., Sterk, Geert Jan, Kikelj, Danijel

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New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus von Durcik, Martina, Cotman, Andrej Emanuel, Toplak, Žan, Možina, Štefan, Skok, Žiga, Szili, Petra Eva, Czikkely, Márton, Maharramov, Elvin, Vu, Thu Hien, Piras, Maria Vittoria, Zidar, Nace, Ilaš, Janez, Zega, Anamarija, Trontelj, Jurij, Pardo, Luis A., Hughes, Diarmaid, Huseby, Douglas, Berruga-Fernández, Tália, Cao, Sha, Simoff, Ivailo, Svensson, Richard, Korol, Sergiy V., Jin, Zhe, Vicente, Francisca, Ramos, Maria C., Mundy, Julia E. A., Maxwell, Anthony, Stevenson, Clare E. M., Lawson, David M., Glinghammar, Björn, Sjöström, Eva, Bohlin, Martin, Oreskär, Joanna, Alvér, Sofie, Janssen, Guido V., Sterk, Geert Jan, Kikelj, Danijel, Pal, Csaba, Tomašič, Tihomir, Peterlin Mašič, Lucija

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To Target or Not to Target ISchistosoma mansoni/I Cyclic Nucleotide Phosphodiesterase 4A? von Zheng, Yang, Schroeder, Susanne, Kanev, Georgi K, Botros, Sanaa S, William, Samia, Sabra, Abdel-Nasser A, Maes, Louis, Caljon, Guy, Gil, Carmen, Ma, Salado, Irene G, Augustyns, Koen, Edink, Ewald, Sijm, Maarten, de Heuvel, Erik, de Esch, Iwan J. P, van der Meer, Tiffany, Siderius, Marco, Sterk, Geert Jan, Brown, David, Leurs, Rob

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Lead Optimization of Phthalazinone Phosphodiesterase Inhibitors as Novel Antitrypanosomal Compounds von Salado, Irene G, Singh, Abhimanyu K, Moreno-Cinos, Carlos, Sakaine, Guna, Siderius, Marco, Van der Veken, Pieter, Matheeussen, An, van der Meer, Tiffany, Sadek, Payman, Gul, Sheraz, Maes, Louis, Sterk, Geert-Jan, Leurs, Rob, Brown, David, Augustyns, Koen

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