Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19 von Hoffman, Robert L, Kania, Robert S, Brothers, Mary A, Davies, Jay F, Ferre, Rose A, Gajiwala, Ketan S, He, Mingying, Hogan, Robert J, Kozminski, Kirk, Li, Lilian Y, Lockner, Jonathan W, Lou, Jihong, Marra, Michelle T, Mitchell, Lennert J, Murray, Brion W, Nieman, James A, Noell, Stephen, Planken, Simon P, Rowe, Thomas, Ryan, Kevin, Smith, George J, Solowiej, James E, Steppan, Claire M, Taggart, Barbara

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Accelerating SLC Transporter Research: Streamlining Knowledge and Validated Tools von Wiedmer, Tabea, Ingles‐Prieto, Alvaro, Goldmann, Ulrich, Steppan, Claire M., Superti‐Furga, Giulio

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Acoustic Ejection Mass Spectrometry for High-Throughput Analysis von Zhang, Hui, Liu, Chang, Hua, Wenyi, Ghislain, Lucien P, Liu, Jianhua, Aschenbrenner, Lisa, Noell, Stephen, Dirico, Kenneth J, Lanyon, Lorraine F, Steppan, Claire M, West, Mike, Arnold, Don W, Covey, Thomas R, Datwani, Sammy S, Troutman, Matthew D

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The current biology of resistin von Steppan, Claire M., Lazar, Mitchell A.

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An Overview of Cell-Based Assay Platforms for the Solute Carrier Family of Transporters von Dvorak, Vojtech, Wiedmer, Tabea, Ingles-Prieto, Alvaro, Altermatt, Patrick, Batoulis, Helena, Bärenz, Felix, Bender, Eckhard, Digles, Daniela, Dürrenberger, Franz, Heitman, Laura H, IJzerman, Adriaan P, Kell, Douglas B, Kickinger, Stefanie, Körzö, Daniel, Leippe, Philipp, Licher, Thomas, Manolova, Vania, Rizzetto, Riccardo, Sassone, Francesca, Scarabottolo, Lia, Schlessinger, Avner, Schneider, Vanessa, Sijben, Hubert J, Steck, Anna-Lena, Sundström, Hanna, Tremolada, Sara, Wilhelm, Maria, Wright Muelas, Marina, Zindel, Diana, Steppan, Claire M, Superti-Furga, Giulio

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Regulation of Fasted Blood Glucose by Resistin von Banerjee, Ronadip R., Rangwala, Shamina M., Shapiro, Jennifer S., Rich, A. Sophie, Rhoades, Ben, Qi, Yong, Wang, Juan, Rajala, Michael W., Pocai, Alessandro, Scherer, Phillipp E., Steppan, Claire M., Ahima, Rexford S., Obici, Silvana, Rossetti, Luciano, Lazar, Mitchell A.

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Activation of SOCS-3 by Resistin von Steppan, Claire M., Wang, Juan, Whiteman, Eileen L., Birnbaum, Morris J., Lazar, Mitchell A.

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Discovery of Small-Molecule CD33 Pre-mRNA Splicing Modulators von Chappie, Thomas A, Abdelmessih, Mario, Ambroise, Claude W, Boehm, Markus, Cai, Mi, Green, Michael, Guilmette, Edward, Steppan, Claire M, Stevens, Lucy M, Wei, Liuqing, Xi, Simon, Hasson, Samuel A

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Structural basis for the in vitro efficacy of nirmatrelvir against SARS-CoV-2 variants von Greasley, Samantha E., Noell, Stephen, Plotnikova, Olga, Ferre, RoseAnn, Liu, Wei, Bolanos, Ben, Fennell, Kimberly, Nicki, Jennifer, Craig, Tim, Zhu, Yuao, Stewart, Al E., Steppan, Claire M.

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A futile metabolic cycle activated in adipocytes by antidiabetic agents von Lazar, Mitchell A, Guan, Hong-Ping, Li, Yong, Jensen, Mette Valentin, Newgard, Christopher B, Steppan, Claire M

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A Family of Tissue-Specific Resistin-like Molecules von Steppan, Claire M., Brown, Elizabeth J., Wright, Christopher M., Bhat, Savitha, Banerjee, Ronadip R., Dai, Charlotte Y., Enders, Gregory H., Silberg, Debra G., Wen, Xiaoming, Wu, Gary D., Lazar, Mitchell A.

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An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19 von Owen, Dafydd R, Allerton, Charlotte M N, Anderson, Annaliesa S, Aschenbrenner, Lisa, Avery, Melissa, Berritt, Simon, Boras, Britton, Cardin, Rhonda D, Carlo, Anthony, Coffman, Karen J, Dantonio, Alyssa, Li, Di, Eng, Heather, Ferre, RoseAnn, Gajiwala, Ketan S, Gibson, Scott A, Greasley, Samantha E, Hurst, Brett L, Kadar, Eugene P, Kalgutkar, Amit S, Lee, Jack C, Lee, Jisun, Liu, Wei, Mason, Stephen W, Noell, Stephen, Novak, Jonathan J, Obach, R Scott, Ogilvie, Kevin, Patel, Nandini C, Pettersson, Martin, Rai, Devendra K, Reese, Matthew R, Sammons, Matthew F, Sathish, Jean G, Singh, Ravi Shankar P, Steppan, Claire M, Stewart, Al E, Tuttle, Jamison B, Updyke, Lawrence, Verhoest, Patrick R, Wei, Liuqing, Yang, Qingyi, Zhu, Yuao

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Hit Triage and Validation in Phenotypic Screening: Considerations and Strategies von Vincent, Fabien, Loria, Paula M., Weston, Andrea D., Steppan, Claire M., Doyonnas, Regis, Wang, Yue-Ming, Rockwell, Kristin L., Peakman, Marie-Claire

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Modeling the mechanism of action of a DGAT1 inhibitor using a causal reasoning platform von Enayetallah, Ahmed E, Ziemek, Daniel, Leininger, Michael T, Randhawa, Ranjit, Yang, Jianxin, Manion, Tara B, Mather, Dawn E, Zavadoski, William J, Kuhn, Max, Treadway, Judith L, des Etages, Shelly Ann G, Gibbs, E Michael, Greene, Nigel, Steppan, Claire M

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Mouse and Human Resistins Impair Glucose Transport in Primary Mouse Cardiomyocytes, and Oligomerization Is Required for This Biological Action von Graveleau, Christophe, Zaha, Vlad G., Mohajer, Arash, Banerjee, Ronadip R., Dudley-Rucker, Nicole, Steppan, Claire M., Rajala, Michael W., Scherer, Philipp E., Ahima, Rexford S., Lazar, Mitchell A., Abel, E. Dale

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C-Aryl glycoside inhibitors of SGLT2: Exploration of sugar modifications including C-5 spirocyclization von Robinson, Ralph P., Mascitti, Vincent, Boustany-Kari, Carine M., Carr, Christopher L., Foley, Patrick M., Kimoto, Emi, Leininger, Michael T., Lowe, Andre, Klenotic, Michelle K., MacDonald, James I., Maguire, Robert J., Masterson, Victoria M., Maurer, Tristan S., Miao, Zhuang, Patel, Jigna D., Préville, Cathy, Reese, Matthew R., She, Li, Steppan, Claire M., Thuma, Benjamin A., Zhu, Tong

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Generation of a VeroE6 Pgp gene knock out cell line and its use in SARS-CoV-2 antiviral study von Zhu, Yuao, Binder, Joe, Yurgelonis, Irina, Rai, Devendra K., Lazarro, Sarah, Costales, Chester, Kobylarz, Keith, McMonagle, Patricia, Steppan, Claire M., Aschenbrenner, Lisa, Anderson, Annaliesa S., Cardin, Rhonda D.

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Resistin and obesity-associated insulin resistance von Steppan, Claire M, Lazar, Mitchell A

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Human Pluripotent Stem Cell-Derived Kidney Model for Nephrotoxicity Studies von Bajaj, Piyush, Rodrigues, A David, Steppan, Claire M, Engle, Sandra J, Mathialagan, Sumathy, Schroeter, Thomas

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The hormone resistin links obesity to diabetes von Lazar, Mitchell A, Steppan, Claire M, Bailey, Shannon T, Bhat, Savitha, Brown, Elizabeth J, Banerjee, Ronadip R, Wright, Christopher M, Patel, Hiralben R, Ahima, Rexford S

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