Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism von Zhang, Xuxiao, Vadas, Oscar, Perisic, Olga, Anderson, Karen E., Clark, Jonathan, Hawkins, Phillip T., Stephens, Len R., Williams, Roger L.

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Lysophosphatidylinositol-acyltransferase-1 (LPIAT1) is required to maintain physiological levels of PtdIns and PtdInsP(2) in the mouse von Anderson, Karen E, Kielkowska, Anna, Durrant, Tom N, Juvin, Veronique, Clark, Jonathan, Stephens, Len R, Hawkins, Phillip T

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Quantification of PtdInsP3 molecular species in cells and tissues by mass spectrometry von Clark, Jonathan, Anderson, Karen E, Juvin, Veronique, Smith, Trevor S, Karpe, Fredrik, Wakelam, Michael J O, Stephens, Len R, Hawkins, Phillip T

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Phosphoproteomic Analyses of Interleukin 2 Signaling Reveal Integrated JAK Kinase-Dependent and -Independent Networks in CD8+ T Cells von Ross, Sarah H., Rollings, Christina, Anderson, Karen E., Hawkins, Phillip T., Stephens, Len R., Cantrell, Doreen A.

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Two distinct functions for PI3-kinases in macropinocytosis von Hoeller, Oliver, Bolourani, Parvin, Clark, Jonathan, Stephens, Len R, Hawkins, Phillip T, Weiner, Orion D, Weeks, Gerald, Kay, Robert R

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Lysophosphatidylinositol-Acyltransferase-1 (LPIAT1) Is Required to Maintain Physiological Levels of PtdIns and PtdInsP2 in the Mouse von Anderson, Karen E., Kielkowska, Anna, Durrant, Tom N., Juvin, Veronique, Clark, Jonathan, Stephens, Len R., Hawkins, Phillip T.

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PI3Kδ Forms Distinct Multiprotein Complexes at the TCR Signalosome in Naïve and Differentiated CD4 + T Cells von Luff, Daisy H, Wojdyla, Katarzyna, Oxley, David, Chessa, Tamara, Hudson, Kevin, Hawkins, Phillip T, Stephens, Len R, Barry, Simon T, Okkenhaug, Klaus

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Regulation of PTEN inhibition by the pleckstrin homology domain of P-REX2 during insulin signaling and glucose homeostasis von Hodakoski, Cindy, Hopkins, Benjamin D., Barrows, Douglas, Mense, Sarah M., Keniry, Megan, Anderson, Karen E., Kern, Philip A., Hawkins, Phillip T., Stephens, Len R., Parsons, Ramon

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Phosphoinositide 3-kinase-dependent activation of Rac von Welch, Heidi C.E., Coadwell, W.John, Stephens, Len R., Hawkins, Phillip T.

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A new approach to measuring phosphoinositides in cells by mass spectrometry von Kielkowska, Anna, Niewczas, Izabella, Anderson, Karen E., Durrant, Tom N., Clark, Jonathan, Stephens, Len R., Hawkins, Phillip T.

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3D time series analysis of cell shape using Laplacian approaches von Du, Cheng-Jin, Hawkins, Phillip T, Stephens, Len R, Bretschneider, Till

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Investigating the effect of arachidonate supplementation on the phosphoinositide content of MCF10a breast epithelial cells von Anderson, Karen E., Juvin, Veronique, Clark, Jonathan, Stephens, Len R., Hawkins, Phillip T.

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Signaling via class IA Phosphoinositide 3-kinases (PI3K) in human, breast-derived cell lines von Juvin, Veronique, Malek, Mouhannad, Anderson, Karen E, Dion, Carine, Chessa, Tamara, Lecureuil, Charlotte, Ferguson, G John, Cosulich, Sabina, Hawkins, Phillip T, Stephens, Len R

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BMX Acts Downstream of PI3K to Promote Colorectal Cancer Cell Survival and Pathway Inhibition Sensitizes to the BH3 Mimetic ABT-737 von Potter, Danielle S, Kelly, Paul, Denneny, Olive, Juvin, Veronique, Stephens, Len R, Dive, Caroline, Morrow, Christopher J

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PtdIns3P and Rac direct the assembly of the NADPH oxidase on a novel, pre-phagosomal compartment during FcR-mediated phagocytosis in primary mouse neutrophils von Anderson, Karen E., Chessa, Tamara A.M., Davidson, Keith, Henderson, Robert B., Walker, Simon, Tolmachova, Tanya, Grys, Katarzyna, Rausch, Oliver, Seabra, Miguel C., Tybulewicz, Victor L.J., Stephens, Len R., Hawkins, Phillip T.

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The cytotoxic T cell proteome and its shaping by the kinase mTOR von Hukelmann, Jens L, Anderson, Karen E, Sinclair, Linda V, Grzes, Katarzyna M, Murillo, Alejandro Brenes, Hawkins, Phillip T, Stephens, Len R, Lamond, Angus I, Cantrell, Doreen A

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Acyl chain selection couples the consumption and synthesis of phosphoinositides von Barneda, David, Janardan, Vishnu, Niewczas, Izabella, Collins, Daniel M, Cosulich, Sabina, Clark, Jonathan, Stephens, Len R, Hawkins, Phillip T

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PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K von Malek, Mouhannad, Kielkowska, Anna, Chessa, Tamara, Anderson, Karen E., Barneda, David, Pir, Pınar, Nakanishi, Hiroki, Eguchi, Satoshi, Koizumi, Atsushi, Sasaki, Junko, Juvin, Véronique, Kiselev, Vladimir Y., Niewczas, Izabella, Gray, Alexander, Valayer, Alexandre, Spensberger, Dominik, Imbert, Marine, Felisbino, Sergio, Habuchi, Tomonori, Beinke, Soren, Cosulich, Sabina, Le Novère, Nicolas, Sasaki, Takehiko, Clark, Jonathan, Hawkins, Phillip T., Stephens, Len R.

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PTEN Regulates PI(3,4)P 2 Signaling Downstream of Class I PI3K von Malek, Mouhannad, Kielkowska, Anna, Chessa, Tamara, Anderson, Karen E, Barneda, David, Pir, Pınar, Nakanishi, Hiroki, Eguchi, Satoshi, Koizumi, Atsushi, Sasaki, Junko, Juvin, Véronique, Kiselev, Vladimir Y, Niewczas, Izabella, Gray, Alexander, Valayer, Alexandre, Spensberger, Dominik, Imbert, Marine, Felisbino, Sergio, Habuchi, Tomonori, Beinke, Soren, Cosulich, Sabina, Le Novère, Nicolas, Sasaki, Takehiko, Clark, Jonathan, Hawkins, Phillip T, Stephens, Len R

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In-depth PtdIns(3,4,5)P3 signalosome analysis identifies DAPP1 as a negative regulator of GPVI-driven platelet function von Durrant, Tom N., Hutchinson, James L., Heesom, Kate J., Anderson, Karen E., Stephens, Len R., Hawkins, Phillip T., Marshall, Aaron J., Moore, Samantha F., Hers, Ingeborg

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