Are Metformin Doses Used in Murine Cancer Models Clinically Relevant? von Chandel, Navdeep S., Avizonis, Dania, Reczek, Colleen R., Weinberg, Samuel E., Menz, Stephan, Neuhaus, Roland, Christian, Sven, Haegebarth, Andrea, Algire, Carolyn, Pollak, Michael

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Identification of the Highly Active, Species Cross-Reactive Complex I Inhibitor BAY-179 von Mowat, Jeffrey, Ehrmann, Alexander H. M, Christian, Sven, Sperl, Carolyn, Menz, Stephan, Günther, Judith, Hillig, Roman C, Bauser, Marcus, Schwede, Wolfgang

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Drug-class specific impact of antivirals on the reproductive capacity of HIV von von Kleist, Max, Menz, Stephan, Huisinga, Wilhelm

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Estimating HIV-1 fitness characteristics from cross-sectional genotype data von Gopalakrishnan, Sathej, Montazeri, Hesam, Menz, Stephan, Beerenwinkel, Niko, Huisinga, Wilhelm

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HIV quasispecies dynamics during pro-active treatment switching: impact on multi-drug resistance and resistance archiving in latent reservoirs von von Kleist, Max, Menz, Stephan, Stocker, Hartmut, Arasteh, Keikawus, Schütte, Christof, Huisinga, Wilhelm

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Prediction of Oral Bioavailability in Rats: Transferring Insights from in Vitro Correlations to (Deep) Machine Learning Models Using in Silico Model Outputs and Chemical Structure... von Schneckener, Sebastian, Grimbs, Sergio, Hey, Jessica, Menz, Stephan, Osmers, Maren, Schaper, Steffen, Hillisch, Alexander, Göller, Andreas H

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Prediction of human pharmacokinetics from chemical structure: combining mechanistic modeling with machine learning von Gruber, Andrea, Führer, Florian, Menz, Stephan, Diedam, Holger, Göller, Andreas H, Schneckener, Sebastian

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A deep neural network: mechanistic hybrid model to predict pharmacokinetics in rat von Führer, Florian, Gruber, Andrea, Diedam, Holger, Göller, Andreas H., Menz, Stephan, Schneckener, Sebastian

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Binding Kinetics Survey of the Drugged Kinome von Georgi, Victoria, Schiele, Felix, Berger, Benedict-Tilman, Steffen, Andreas, Marin Zapata, Paula A, Briem, Hans, Menz, Stephan, Preusse, Cornelia, Vasta, James D, Robers, Matthew B, Brands, Michael, Knapp, Stefan, Fernández-Montalván, Amaury

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sOAR: a tool for modelling optimal animal life‐history strategies in cyclic environments von Schaefer, Merlin, Menz, Stephan, Jeltsch, Florian, Zurell, Damaris

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Abstract 3248: Identification and optimization of a highly active, cross reactive Complex-1 inhibitor von Mowat, Jeffrey, Christian, Sven, Sperl, Carolyn, Ehrmann, Alexander, Menz, Stephan, Guenther, Judith, Hillig, Roman, Bauser, Marcus, Haegebarth, Andrea, Schwede, Wolfgang

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Estimating HIV-1 Fitness Characteristics from Cross-Sectional Genotype Data: e1003886 von Gopalakrishnan, Sathej, Montazeri, Hesam, Menz, Stephan, Beerenwinkel, Niko, Huisinga, Wilhelm

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Abstract 1126: Differential effects of metformin and phenformin vs. other complex 1 inhibitors in vitro and in vivo von Algire, Carolyn, Ehrmann, Alexander, Christian, Sven, Neuhaus, Roland, Menz, Stephan, Schwede, Wolfgang, Haerter, Michael, Haegebarth, Andrea

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Abstract 223: Comparison of human-specific versus cross-reactive Complex I inhibitor for in vivo tumor efficacy von Christian, Sven, Algire, Carolyn, Schwede, Wolfgang, Mowat, Jeffrey S., Ehrmann, Alexander, Menz, Stephan, Bauser, Marcus, Haegebarth, Andrea

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BRD-810 is a highly selective MCL1 inhibitor with optimized in vivo clearance and robust efficacy in solid and hematological tumor models von Rauh, Ulrike, Wei, Guo, Serrano-Wu, Michael, Kosmidis, Georgios, Kaulfuss, Stefan, Siegel, Franziska, Thede, Kai, McFarland, James, Lemke, Christopher T., Werbeck, Nicolas, Nowak-Reppel, Katrin, Pilari, Sabine, Menz, Stephan, Ocker, Matthias, Zhang, Weiqun, Davis, Kyle, Poncet-Montange, Guillaume, Roth, Jennifer, Daniels, Douglas, Kaushik, Virendar K., Hubbard, Brian, Ziegelbauer, Karl, Golub, Todd R.

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Abstract 506: ANJ810 is a highly selective novel MCL1 inhibitor with optimized in vivo clearance showing robust efficacy in preclinical solid and hematological tumor models von Rauh, Ulrike, Wei, Guo, Serrano-Wu, Michael, Kosmidis, Georgios, Kaulfuss, Stefan, Siegel, Franziska, Thede, Kai, McFarland, James, Lemke, Christopher, Werbeck, Nicolas, Nowak-Reppel, Katrin, Pillari, Sabine, Menz, Stephan, Ocker, Matthias, Hubbard, Brian, Kaushik, Virendar, Ziegelbauer, Karl, Golub, Todd

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Hybrid Stochastic--Deterministic Solution of the Chemical Master Equation von Menz, Stephan, Latorre, Juan C, Schutte, Christof, Huisinga, Wilhelm

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Drug-Class Specific Impact of Antivirals on the Reproductive Capacity of HIV: e1000720 von Kleist, Max von, Menz, Stephan, Huisinga, Wilhelm

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Hybrid stochastic-deterministic approaches for simulation and analysis of biochemical reaction networks von Menz, Stephan

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Quantifying the degree of persistence in random amoeboid motion based on the Hurst exponent of fractional Brownian motion von Makarava, Natallia, Menz, Stephan, Theves, Matthias, Huisinga, Wilhelm, Beta, Carsten, Holschneider, Matthias

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