Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes von Dubovsky, Jason A., Beckwith, Kyle A., Natarajan, Gayathri, Woyach, Jennifer A., Jaglowski, Samantha, Zhong, Yiming, Hessler, Joshua D., Liu, Ta-Ming, Chang, Betty Y., Larkin, Karilyn M., Stefanovski, Matthew R., Chappell, Danielle L., Frissora, Frank W., Smith, Lisa L., Smucker, Kelly A., Flynn, Joseph M., Jones, Jeffrey A., Andritsos, Leslie A., Maddocks, Kami, Lehman, Amy M., Furman, Richard, Sharman, Jeff, Mishra, Anjali, Caligiuri, Michael A., Satoskar, Abhay R., Buggy, Joseph J., Muthusamy, Natarajan, Johnson, Amy J., Byrd, John C.

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Bruton's tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL) von Woyach, Jennifer A., Bojnik, Engin, Ruppert, Amy S., Stefanovski, Matthew R., Goettl, Virginia M., Smucker, Kelly A., Smith, Lisa L., Dubovsky, Jason A., Towns, William H., MacMurray, Jessica, Harrington, Bonnie K., Davis, Melanie E., Gobessi, Stefania, Laurenti, Luca, Chang, Betty Y., Buggy, Joseph J., Efremov, Dimitar G., Byrd, John C., Johnson, Amy J.

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Pharmacokinetics and Tissue Disposition of Lenalidomide in Mice von Rozewski, Darlene M., Herman, Sarah E. M., Towns, William H., Mahoney, Emilia, Stefanovski, Matthew R., Shin, Jungook D., Yang, Xiaoxia, Gao, Yue, Li, Xiaobai, Jarjoura, David, Byrd, John C., Johnson, Amy J., Phelps, Mitch A.

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The CD37-targeted antibody–drug conjugate IMGN529 is highly active against human CLL and in a novel CD37 transgenic murine leukemia model von Beckwith, K A, Frissora, F W, Stefanovski, M R, Towns, W H, Cheney, C, Mo, X, Deckert, J, Croce, C M, Flynn, J M, Andritsos, L A, Jones, J A, Maddocks, K J, Lozanski, G, Byrd, J C, Muthusamy, N

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Therapeutic role of interleukin 22 in abdominal bacterial infection in mice (VAC8P.1049) von Zheng, Mingquan, Kumar, Pawan, Stefanovski, Matthew, Pociask, Derek, Good, Misty

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The role of CD4+ T cell subsets in the clearance of Pneumocystis murina pneumonia in mice (MPF6P.734) von Zheng, Mingquan, Ripple, Michael, Yu, Amy, Cleveland, Hillary, Stefanovski, Matthew, Chen, Kong, Kolls, Jay

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Milatuzumab-Conjugated Liposomes as Targeted Dexamethasone Carriers for Therapeutic Delivery in CD74+ B-cell Malignancies von YICHENG MAO, TRIANTAFILLOU, Georgia, GOLDENBERG, David M, LEE, Robert J, BYRD, John C, MUTHUSAMY, Natarajan, HERTLEIN, Erin, TOWNS, William, STEFANOVSKI, Matthew, XIAOKUI MO, JARJOURA, David, PHELPS, Mitch, MARCUCCI, Guido, JAMES LEE, Ly

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A Transgenic Mouse Model of Aggressive B-Cell Malignancy for Evaluating Anti-Human CD37 Therapeutics von Beckwith, Kyle A, Frissora, Frank W, Stefanovski, Matthew R, Deckert, Jutta, Croce, Carlo M, Mo, Xiaokui, Jarjoura, David, Byrd, John C., Muthusamy, Natarajan

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Global Inhibition of Bruton's Tyrosine Kinase (BTK) Delays the Development and Expansion of Chronic Lymphocytic Leukemia (CLL) in the TCL1 Mouse Model of Disease von Woyach, Jennifer A., Stefanovski, Matthew R, Goettl, Virginia, Ruppert, Amy S., Smucker, Kelly A, Smith, Lisa L., Dubovsky, Jason A, Towns, William H., MacMurray, Jessica, Davis, Melanie E., Mao, Yicheng, Chang, Betty Y., Buggy, Joseph J., Byrd, John C., Johnson, Amy J

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Ibrutinib Is an Irreversible Molecular Inhibitor of Interleukin-2 Inducible Kinase: Expanding Therapeutic Potential and Modulating a Th1 Selective Pressure in CD4 T-Cells von Dubovsky, Jason A, Beckwith, Kyle A, Woyach, Jennifer A., Jaglowski, Samantha M., Hessler, Joshua, Chang, Betty Y., Larkin, Karilyn, Stefanovski, Matthew R, Frissora, Frank W, Smith, Lisa L., Smucker, Kelly A, Flynn, Joseph M., Jones, Jeffrey A., Andritsos, Leslie A, Maddocks, Kami, Lehman, Amy, Furman, Richard R., Sharman, Jeff, Mishra, Anjali, Caligiuri, Michael A., Buggy, Joseph J., Muthusamy, Natarajan, Johnson, Amy J, Byrd, John C.

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Abstract 492: Ibrutinib inhibits Interleukin-2 inducible kinase, driving a Th1 selective pressure in human leukemia patients that serves to alleviate tumor-induced immunosupression von Dubovsky, Jason A., Beckwith, Kyle A., Natarajan, Gayathri, Woyach, Jennifer A., Jaglowski, Samantha, Hessler, Joshua, Liu, Ta-Ming, Chang, Betty Y., Larkin, Karilyn M., Stefanovski, Matthew R., Frissora, Frank W., Smith, Lisa L., Smucker, Kelly A., Flynn, Joseph M., Jones, Jeffrey A., Andritsos, Leslie A., Maddocks, Kami, Lehman, Amy M., Furman, Richard, Sharman, Jeff, Mishra, Anjali, Caligiuri, Michael A., Satoskar, Abhay R., Buggy, Joseph J., Muthusamy, Natarajan, Johnson, Amy J., Byrd, John C.

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The the TypeScript Workshop: A Practical Guide to Confident, Effective TypeScript Programming von Grynhaus, Ben, Hudgens, Jordan, Hunte, Rayon, Morgan, Matt, Stefanovski, Wekoslav

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Saturated fatty acid concentrations are predictive of insulin sensitivity and beta cell compensation in dogs von Peloquin, Matthew, Tovar, Ashley, Graves, Jessica L., Stefanovski, Darko, Tucker, Katya, Marietti, Entonio, Greenwood, Karen, Halioua-Haubold, Celine-Lea, Juarez-Salinas, Dina

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Investigation of synovial fluid lubricants and inflammatory cytokines in the horse: a comparison of recombinant equine interleukin 1 beta-induced synovitis and joint lavage models von Watkins, Amanda, Fasanello, Diana, Stefanovski, Darko, Schurer, Sydney, Caracappa, Katherine, D'Agostino, Albert, Costello, Emily, Freer, Heather, Rollins, Alicia, Read, Claire, Su, Jin, Colville, Marshall, Paszek, Matthew, Wagner, Bettina, Reesink, Heidi

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Evaluation of locking compression plate fixation of the distal phalanx to the hoof wall as a potential therapy for laminitis von Lean, Natasha E., Zedler, Steven T., Van Eps, Andrew William, Engiles, Julie B., Ford, Matthew, Stefanovski, Darko, Walsh, Donald Mark, Pollitt, Christopher C.

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Pharmacokinetics and pharmacodynamics of oral and intravenous metoprolol tartrate in clinically healthy horses von Luethy, Daniela, Robinson, Mary A., Stefanovski, Darko, Haughan, Joanne, Torcivia, Catherine, Kowalski, Alycia, Ford, Matthew, You, Youwen, Missanelli, Jaclyn, Slack, Joann

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Common variant at 16p11.2 conferring risk of psychosis von Steinberg, S, de Jong, S, Pietiläinen, O P H, Lin, K, Papiol, S, Huttenlocher, J, Sigurdsson, E, Giegling, I, Breuer, R, Fraser, G, Walker, N, Melle, I, Djurovic, S, Tuulio-Henriksson, A, Suvisaari, J, Lönnqvist, J, Paunio, T, Olsen, L, Ingason, A, Pirinen, M, Strengman, E, Hougaard, D M, Ørntoft, T, Didriksen, M, Abramova, L, Kaleda, V, Arrojo, M, Arango, C, Etain, B, Bellivier, F, Méary, A, Schürhoff, F, Szoke, A, Ribolsi, M, Magni, V, Siracusano, A, Sperling, S, Rossner, M, Christiansen, C, Kiemeney, L A, Franke, B, Veldink, J, Curran, S, Bolton, P, Poot, M, Rehnstrom, K, Freitag, C M, Magnusson, P, Saemundsen, E, Martsenkovsky, I, Bikshaieva, I, Martsenkovska, I, Vashchenko, O, Raleva, M, Paketchieva, K, Pejovic Milovancevic, M, Naneishvili, N, Mikeladze, N, Vincent, J B, Farmer, A, Mitchell, P B, Wright, A, Schofield, P R, Fullerton, J M, Montgomery, G W, Rubino, I A, Kenis, G, Bitter, I, Terenius, L, Jönsson, E G, Bakker, S, van Os, J, Jablensky, A, Powell, J, Murray, R, Corvin, A, Gill, M, Morris, D, O'Neill, F A, Kendler, K, Riley, B, Craddock, N, O'Donovan, M C, Thorsteinsdottir, U, Ehrenreich, H, Carracedo, A, Golimbet, V, Børglum, A D, Mortensen, P B, Werge, T, Ophoff, R A, Rietschel, M, Cichon, S, Ruggeri, M, Tosato, S, Palotie, A, St Clair, D, Rujescu, D, Collier, D A, Stefansson, K

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Fracture Limits of Maxillary Fourth Premolar Teeth in Domestic Dogs Under Applied Forces von Soltero-Rivera, Maria, Elliott, Matthew I, Hast, Michael W, Shetye, Snehal S, Castejon-Gonzalez, Ana C, Villamizar-Martinez, Lenin A, Stefanovski, Darko, Reiter, Alexander M

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Estimating Hepatic Glucokinase Activity Using a Simple Model of Lactate Kinetics von Stefanovski, Darko, Youn, Jang H, Rees, Matthew, Watanabe, Richard M, Ader, Marilyn, Ionut, Viorica, Jackson, Anne U, Boehnke, Michael, Collins, Francis S, Bergman, Richard N

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FAHRZEUGSYSTEM ZUM BEREITSTELLEN EINER ERINNERUNG, DASS ZUMINDEST EINE MOBILE ELEKTRONISCHE EINRICHTUNG IN EINEM FAHRGASTRAUM EINES FAHRZEUGS NACH EINEM FAHRZEUGZUGRIFFSEREIGNIS ZU... von Hansen, Cody R, Stefanovski, James A, Highstrom, Matthew M, Gellatly, Andrew W, Grost, Timothy J

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