Subfield-specific immediate early gene expression associated with hippocampal long-term potentiation in vivo von French, P. J., O'Connor, V., Jones, M. W., Davis, S., Errington, M. L., Voss, K., Truchet, B., Wotjak, C., Stean, T., Doyère, V., Maroun, M., Laroche, S., Bliss, T. V. P.

Volltext

SB-243213; a selective 5-HT2C receptor inverse agonist with improved anxiolytic profile : Lack of tolerance and withdrawal anxiety von WOOD, M. D, REAVILL, C, RILEY, G, HOLLAND, V, BROMIDGE, S. M, FORBES, I. T, MIDDLEMISS, D. N, TRAIL, B, WILSON, A, STEAN, T, KENNETT, G. A, LIGHTOWLER, S, BLACKBURN, T. P, THOMAS, D, GAGER, T. L

Volltext

Seizure-induced gene expression in area CA1 of the mouse hippocampus von French, P. J., O'Connor, V., Voss, K., Stean, T., Hunt, S. P., Bliss, T. V. P.

Volltext

The voltage-gated sodium channel Na(v)1.9 is an effector of peripheral inflammatory pain hypersensitivity von Amaya, Fumimasa, Wang, Haibin, Costigan, Michael, Allchorne, Andrew J, Hatcher, Jon P, Egerton, Julie, Stean, Tania, Morisset, Valerie, Grose, David, Gunthorpe, Martin J, Chessell, Iain P, Tate, Simon, Green, Paula J, Woolf, Clifford J

Volltext

Identification of (-)-cis-6-acetyl-4S-(3-chloro-4-fluoro-benzoylamino)-3,4-dihydro-2,2-dimethyl-2H-benzo[b]pyran-3S-ol as a potential antimigraine agent von CHAN, W. N, EVANS, J. M, HADLEY, M. S, HERDON, H. J, JERMAN, J. C, PARSONS, A. A, READ, S. J, STEAN, T. O, THOMPSON, M, UPTON, N

Volltext

LTP but not seizure is associated with up-regulation of AKAP-150 von Génin, A., French, P., Doyère, V., Davis, S., Errington, M. L., Maroun, M., Stean, T., Truchet, B., Webber, M., Wills, T., Richter-Levin, G., Sanger, G., Hunt, S. P., Mallet, J., Laroche, S., Bliss, T. V. P., O'Connor, V.

Volltext

Profile of SB‐204269, a mechanistically novel anticonvulsant drug, in rat models of focal and generalized epileptic seizures von Upton, Neil, Blackburn, Tom P., Campbell, Colin A., Cooper, Duncan, Evans, Martyn L., Herdon, Hugh J., King, Penny D., Ray, Alison M., Stean, Tania O., Chan, Wai N., Evans, John M., Thompson, Mervyn

Volltext

Synthesis of Novel trans-4-(Substituted-benzamido)-3,4-dihydro-2H-benzo[b]pyran-3-ol Derivatives as Potential Anticonvulsant Agents with a Distinctive Binding Profile von Chan, Wai N, Evans, John M, Hadley, Michael S, Herdon, Hugh J, Jerman, Jeffrey C, Morgan, Helen K. A, Stean, Tania O, Thompson, Mervyn, Upton, Neil, Vong, Antonio K

Volltext

Characterization of the binding of [3H]‐SB‐204269, a radiolabelled form of the new anticonvulsant SB‐204269, to a novel binding site in rat brain membranes von Herdon, Hugh J., Jerman, Jeffrey C., Stean, Tania O., Middlemiss, Derek N., Chan, Wai N., Vong, Antonio K., Evans, John M., Thompson, Mervyn, Upton, Neil

Volltext

Evaluation of a series of anticonvulsant 1,2,3,4-tetrahydroisoquinolinyl-benzamides von CHAN, W. N, HADLEY, M. S, WARD, R. W, HARLING, J. D, HERDON, H. J, ORLEK, B. S, RILEY, G. J, STEAD, R. E. A, STEAN, T. O, THOMPSON, M, UPTON, N

Volltext

Characterization of SB‐269970‐A, a selective 5‐HT7 receptor antagonist von Hagan, Jim J, Price, Gary W, Jeffrey, Phillip, Deeks, Nigel J, Stean, Tania, Piper, David, Smith, Martin I, Upton, Neil, Medhurst, Andrew D, Middlemiss, Derek N, Riley, Graham J, Lovell, Peter J, Bromidge, Steven M, Thomas, David R

Volltext

GABA(B(1)) splice variant mRNAs are differentially affected by electroshock induced seizure in rats von Billinton, A, Stean, T O, Bowery, N G, Upton, N

Volltext

Identification of a series of 1,2,3,4-tetrahydroisoquinolinyl- benzamides with potential anticonvulsant activity von Chan, Wai N., Hadley, Michael S, Harling, John D., Herdon, Hugh J., Jerman, Jeffrey C., Orlek, Barry S., Stean, Tania O., Thompson, Mervyn, Upton, Neil, Ward, Robert W.

Volltext

SB‐656104‐A, a novel selective 5‐HT7 receptor antagonist, modulates REM sleep in rats von Thomas, David R, Melotto, Sergio, Massagrande, Mario, Gribble, Andrew D, Jeffrey, Phillip, Stevens, Alexander J, Deeks, Nigel J, Eddershaw, Peter J, Fenwick, Susan H, Riley, Graham, Stean, Tania, Scott, Claire M, Hill, Matthew J, Middlemiss, Derek N, Hagan, Jim J, Price, Gary W, Forbes, Ian T

Volltext

SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist von Kennett, G A, Wood, M D, Bright, F, Trail, B, Riley, G, Holland, V, Avenell, K Y, Stean, T, Upton, N, Bromidge, S, Forbes, I T, Brown, A M, Middlemiss, D N, Blackburn, T P

Volltext

Epileptogenesis and enhanced prepulse inhibition in GABA(B1)-deficient mice von Prosser, H M, Gill, C H, Hirst, W D, Grau, E, Robbins, M, Calver, A, Soffin, E M, Farmer, C E, Lanneau, C, Gray, J, Schenck, E, Warmerdam, B S, Clapham, C, Reavill, C, Rogers, D C, Stean, T, Upton, N, Humphreys, K, Randall, A, Geppert, M, Davies, C H, Pangalos, M N

Volltext

Characterization of SB‐271046: A potent, selective and orally active 5‐HT6 receptor antagonist von Routledge, Carol, Bromidge, Steven M, Moss, Stephen F, Price, Gary W, Hirst, Warren, Newman, Helen, Riley, Graham, Gager, Tracey, Stean, Tania, Upton, Neil, Clarke, Stephen E, Brown, Anthony M, Middlemiss, Derek N

Volltext

SB 242084, a Selective and Brain Penetrant 5-HT 2C Receptor Antagonist von KENNETT, G.A., WOOD, M.D., BRIGHT, F., TRAIL, B., RILEY, G., HOLLAND, V., AVENELL, K.Y., STEAN, T., UPTON, N., BROMIDGE, S., FORBES, I.T., BROWN, A.M., MIDDLEMISS, D.N., BLACKBURN, T.P.

Volltext

Studies on the role of 5-HT2C and 5-HT2B receptors in regulating generalised seizure threshold in rodents von UPTON, N, STEAN, T, MIDDLEMISS, D, BLACKBURN, T, KENNETT, G

Volltext

LABORAS™: Initial pharmacological validation of a system allowing continuous monitoring of laboratory rodent behaviour von Quinn, Leann P, Stean, Tania O, Trail, Brenda, Duxon, Mark S, Stratton, Sharon C, Billinton, Andrew, Upton, Neil

Volltext