pH-dependent reaction triggering in PmHMGR crystals for time-resolved crystallography von Purohit, Vatsal, Steussy, Calvin N., Rosales, Anthony R., Critchelow, Chandra J., Schmidt, Tim, Helquist, Paul, Wiest, Olaf, Mesecar, Andrew, Cohen, Aina E., Stauffacher, Cynthia V.

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Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase von Chen, Chun-Liang, Paul, Lake N., Mermoud, James C., Steussy, Calvin Nicklaus, Stauffacher, Cynthia V.

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The Increasingly Complex Mechanism of HMG-CoA Reductase von Haines, Brandon E, Wiest, Olaf, Stauffacher, Cynthia V

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Mevalonate 5-diphosphate mediates ATP binding to the mevalonate diphosphate decarboxylase from the bacterial pathogen Enterococcus faecalis von Chen, Chun-Liang, Mermoud, James C., Paul, Lake N., Steussy, Calvin Nicklaus, Stauffacher, Cynthia V.

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Heterogeneity in Lowe Syndrome: Mutations Affecting the Phosphatase Domain of OCRL1 Differ in Impact on Enzymatic Activity and Severity of Cellular Phenotypes von Lee, Jennifer J, Ramadesikan, Swetha, Black, Adrianna F, Christoffer, Charles, Pacheco, Andres F Pacheco, Subramanian, Sneha, Hanna, Claudia B, Barth, Gillian, Stauffacher, Cynthia V, Kihara, Daisuke, Aguilar, Ruben Claudio

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Molecular Modeling of the Reaction Pathway and Hydride Transfer Reactions of HMG-CoA Reductase von Haines, Brandon E, Steussy, C. Nicklaus, Stauffacher, Cynthia V, Wiest, Olaf

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Targeting Enterococcus faecalis HMG-CoA reductase with a non-statin inhibitor von Bose, Sucharita, Steussy, C. Nicklaus, López-Pérez, Daneli, Schmidt, Tim, Kulathunga, Samadhi C., Seleem, Mohamed N., Lipton, Mark, Mesecar, Andrew D., Rodwell, Victor W., Stauffacher, Cynthia V.

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Computational Study of Base-Catalyzed Thiohemiacetal Decomposition in Pseudomonas mevalonii HMG-CoA Reductase von Patel, Himani N., Haines, Brandon E., Stauffacher, Cynthia V., Helquist, Paul, Wiest, Olaf

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Synthesis of Caged HMG-CoA Reductase Substrates for the Elucidation of Cellular Pathways von O’Connell, Ryan J., Dolphin, Nicholas J., Ferraudi, Guillermo, Lee, Mijoon, Stauffacher, Cynthia V., Helquist, Paul, Wiest, Olaf

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Essential amino acids in the Plant-Conserved and Class-Specific Regions of cellulose synthases von Olek, Anna T, Rushton, Phillip S, Kihara, Daisuke, Ciesielski, Peter, Aryal, Uma K, Zhang, Zicong, Stauffacher, Cynthia V, McCann, Maureen C, Carpita, Nicholas C

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The nuclear mitotic apparatus protein NuMA controls rDNA transcription and mediates the nucleolar stress response in a p53-independent manner von Jayaraman, Swaathi, Chittiboyina, Shirisha, Bai, Yunfeng, Abad, Patricia C, Vidi, Pierre-Alexandre, Stauffacher, Cynthia V, Lelièvre, Sophie A

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Conformational Dynamics in the Binding-Protein-Independent Mutant of the Escherichia coli Maltose Transporter, MalG511, and Its Interaction with Maltose Binding Protein von Bajaj, Ruchika, Park, Mariana I, Stauffacher, Cynthia V, Davidson, Amy L

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Microsecond timescale MD simulations at the transition state of PmHMGR predict remote allosteric residues von Quinn, Taylor R, Steussy, Calvin N, Haines, Brandon E, Lei, Jinping, Wang, Wei, Fu Kit Sheong, Stauffacher, Cynthia V, Huang, Xuhui, Per-Ola Norrby, Helquist, Paul, Wiest, Olaf

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Rice Cellulose SynthaseA8 Plant-Conserved Region Is a Coiled-Coil at the Catalytic Core Entrance von Rushton, Phillip S., Olek, Anna T., Makowski, Lee, Badger, John, Steussy, C. Nicklaus, Carpita, Nicholas C., Stauffacher, Cynthia V.

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Microsecond timescale MD simulations at the transition state of Pm HMGR predict remote allosteric residues von Quinn, Taylor R, Steussy, Calvin N, Haines, Brandon E, Lei, Jinping, Wang, Wei, Sheong, Fu Kit, Stauffacher, Cynthia V, Huang, Xuhui, Norrby, Per-Ola, Helquist, Paul, Wiest, Olaf

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Nonfouling NTA-PEG-Based TEM Grid Coatings for Selective Capture of Histidine-Tagged Protein Targets from Cell Lysates von Benjamin, Christopher J, Wright, Kyle J, Hyun, Seok-Hee, Krynski, Kyle, Yu, Guimei, Bajaj, Ruchika, Guo, Fei, Stauffacher, Cynthia V, Jiang, Wen, Thompson, David H

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Crystal Structure of a Statin Bound to a Class II Hydroxymethylglutaryl-CoA Reductase von Tabernero, Lydia, Rodwell, Victor W., Stauffacher, Cynthia V.

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Crystal Structure of the Human B-form Low Molecular Weight Phosphotyrosyl Phosphatase at 1.6-Å Resolution von Zabell, Adam P.R., Schroff, Alfred D., Bain, Bornadata Evans, Van Etten, Robert L., Wiest, Olaf, Stauffacher, Cynthia V.

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Substrate-Induced Closure of the Flap Domain in the Ternary Complex Structures Provides Insights into the Mechanism of Catalysis by 3-hydroxy-3-methylglutaryl-CoA Reductase von Tabernero, Lydia, Bochar, Daniel A., Rodwell, Victor W., Stauffacher, Cynthia V.

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In Vitro Reassembly of the Ribose ATP-binding Cassette Transporter Reveals a Distinct Set of Transport Complexes von Clifton, Matthew C., Simon, Michael J., Erramilli, Satchal K., Zhang, Huide, Zaitseva, Jelena, Hermodson, Mark A., Stauffacher, Cynthia V.

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