Glioma IL13Rα2 is associated with mesenchymal signature gene expression and poor patient prognosis von Brown, Christine E, Warden, Charles D, Starr, Renate, Deng, Xutao, Badie, Behnam, Yuan, Yate-Ching, Forman, Stephen J, Barish, Michael E

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Spatial organization of heterogeneous immunotherapy target antigen expression in high-grade glioma von Barish, Michael E., Weng, Lihong, Awabdeh, Dina, Zhai, Yubo, Starr, Renate, D'Apuzzo, Massimo, Rockne, Russell C., Li, Haiqing, Badie, Behnam, Forman, Stephen J., Brown, Christine E.

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Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3 von Yang, Fan, Brown, Christine, Buettner, Ralf, Hedvat, Michael, Starr, Renate, Scuto, Anna, Schroeder, Anne, Jensen, Michael, Jove, Richard

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Targeting Wnt signaling for improved glioma immunotherapy von Gutova, Margarita, Hibbard, Jonathan C, Ma, Eric, Natri, Heini M, Adhikarla, Vikram, Chimge, Nyam-Osor, Qiu, Runxiang, Nguyen, Cu, Melendez, Elizabeth, Aguilar, Brenda, Starr, Renate, Yin, Holly, Rockne, Russel C, Ono, Masaya, Banovich, Nicholas E, Yuan, Yate-Ching, Brown, Christine E, Kahn, Michael

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A novel berbamine derivative inhibits cell viability and induces apoptosis in cancer stem-like cells of human glioblastoma, via up-regulation of miRNA-4284 and JNK/AP-1 signaling von Yang, Fan, Nam, Sangkil, Brown, Christine E, Zhao, Robin, Starr, Renate, Ma, Yuelong, Xie, Jun, Horne, David A, Malkas, Linda H, Jove, Richard, Hickey, Robert J

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580 Mapping interstitial fluid flow in the brain to improve CAR T cell trafficking and efficacy von Gutova, Margarita, Woodall, Ryan, Ma, Eric, Esparza, Cora, Salvary, Vanessa, Aguilar, Brenda, Starr, Renate, Badie, Behnam, Alizadeh, Darya, Munson, Jennifer M, Rockne, Russell C, Brown, Christine

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Antibody-based redirection of universal Fabrack-CAR T cells selectively kill antigen bearing tumor cells von Kuo, Yi-Chiu, Kuo, Cheng-Fu, Jenkins, Kurt, Hung, Alfur Fu-Hsin, Chang, Wen-Chung, Park, Miso, Aguilar, Brenda, Starr, Renate, Hibbard, Jonathan, Brown, Christine, Williams, John C

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1525 Initial clinical experience with chlorotoxin-redirected CAR T cells for patients with recurrent glioblastoma von Aftabizadeh, Maryam, Blanchard, Marie Suzette, Stiller, Tracey, Natri, Heini M, Aguilar, Brenda, Wagner, Jamie R, Paul, Jinny A, Starr, Renate, Ressler, Julie A, Kilpatrick, Julie, Myers-McNamara, Paige, D’Apuzzo, Massimo, Benovich, Nicholas, Forman, Stephen J, Barish, Michael E, Badie, Behnam, Brown, Christine E

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1520 Phase I trial evaluating locoregionally-delivered IL13Rα2-targeting CAR T cells in high-grade glioma von Brown, Christine E, Hibbard, Jonathan C, Alizadeh, Darya, Blanchard, Marie Suzette, Natri, Heini M, Wang, Dongrui, Ostberg, Julie R, Aguilar, Brenda, Wagner, Jamie R, Paul, Jinny A, Starr, Renate, Filippov, Aleksandr, Chaudhry, Ammar, Ressler, Julie A, Kilpatrick, Julie, Myers-McNamara, Paige, Chen, Mike, Wang, Leo D, Rockne, Russell C, Georges, Joseph, Portnow, Jana, Barish, Michael E, D’Apuzzo, Massimo, Banovich, Nicholas E, Forman, Stephen J, Badie, Behnam

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Cytokine induction of VCAM-1 but not IL13Rα2 on glioma cells: a tale of two antibodies von Mahadev, Vaidehi, Starr, Renate, Wright, Sarah L, Martinez, Catalina, Jensen, Michael C, Barish, Michael E, Forman, Stephen J, Brown, Christine E

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Bioactivity and Safety of IL13R alpha 2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma von Brown, Christine E, Badie, Behnam, Barish, Michael E, Weng, Lihong, Ostberg, Julie R, Chang, Wen-Chung, Naranjo, Araceli, Starr, Renate, Wagner, Jamie, Wright, Christine, Zhai, Yubo, Bading, James R, Ressler, Julie A, Portnow, Jana, D'Apuzzo, Massimo, man, Stephen J, Jensen, Michael C

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Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy von Brown, Christine E, Alizadeh, Darya, Starr, Renate, Weng, Lihong, Wagner, Jamie R, Naranjo, Araceli, Ostberg, Julie R, Blanchard, M. Suzette, Kilpatrick, Julie, Simpson, Jennifer, Kurien, Anita, Priceman, Saul J, Wang, Xiuli, Harshbarger, Todd L, D’Apuzzo, Massimo, Ressler, Julie A, Jensen, Michael C, Barish, Michael E, Chen, Mike, Portnow, Jana, Forman, Stephen J, Badie, Behnam

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Optimization of IL13Rα2-Targeted Chimeric Antigen Receptor T Cells for Improved Anti-tumor Efficacy against Glioblastoma von Brown, Christine E., Aguilar, Brenda, Starr, Renate, Yang, Xin, Chang, Wen-Chung, Weng, Lihong, Chang, Brenda, Sarkissian, Aniee, Brito, Alfonso, Sanchez, James F., Ostberg, Julie R., D’Apuzzo, Massimo, Badie, Behnam, Barish, Michael E., Forman, Stephen J.

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Bioactivity and Safety of IL13Rα2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma von Brown, Christine E, Badie, Behnam, Barish, Michael E, Weng, Lihong, Ostberg, Julie R, Chang, Wen-Chung, Naranjo, Araceli, Starr, Renate, Wagner, Jamie, Wright, Christine, Zhai, Yubo, Bading, James R, Ressler, Julie A, Portnow, Jana, D'Apuzzo, Massimo, Forman, Stephen J, Jensen, Michael C

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IL15 Enhances CAR-T Cell Antitumor Activity by Reducing mTORC1 Activity and Preserving Their Stem Cell Memory Phenotype von Alizadeh, Darya, Wong, Robyn A, Yang, Xin, Wang, Dongrui, Pecoraro, Joseph R, Kuo, Cheng-Fu, Aguilar, Brenda, Qi, Yue, Ann, David K, Starr, Renate, Urak, Ryan, Wang, Xiuli, Forman, Stephen J, Brown, Christine E

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T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia von Mardiros, Armen, Dos Santos, Cedric, McDonald, Tinisha, Brown, Christine E., Wang, Xiuli, Budde, L. Elizabeth, Hoffman, Lauren, Aguilar, Brenda, Chang, Wen-Chung, Bretzlaff, William, Chang, Brenda, Jonnalagadda, Mahesh, Starr, Renate, Ostberg, Julie R., Jensen, Michael C., Bhatia, Ravi, Forman, Stephen J.

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CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies von Wang, Dongrui, Prager, Briana C, Gimple, Ryan C, Aguilar, Brenda, Alizadeh, Darya, Tang, Hongzhen, Lv, Deguan, Starr, Renate, Brito, Alfonso, Wu, Qiulian, Kim, Leo J Y, Qiu, Zhixin, Lin, Peng, Lorenzini, Michael H, Badie, Behnam, Forman, Stephen J, Xie, Qi, Brown, Christine E, Rich, Jeremy N

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PET of Adoptively Transferred Chimeric Antigen Receptor T Cells with 89Zr-Oxine von Weist, Michael R, Starr, Renate, Aguilar, Brenda, Chea, Junie, Miles, Joshua K, Poku, Erasmus, Gerdts, Ethan, Yang, Xin, Priceman, Saul J, man, Stephen J, Colcher, David, Brown, Christine E, Shively, John E

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IFNγ Is Critical for CAR T Cell-Mediated Myeloid Activation and Induction of Endogenous Immunity von Alizadeh, Darya, Wong, Robyn A, Gholamin, Sharareh, Maker, Madeleine, Aftabizadeh, Maryam, Yang, Xin, Pecoraro, Joseph R, Jeppson, John D, Wang, Dongrui, Aguilar, Brenda, Starr, Renate, Larmonier, Claire B, Larmonier, Nicolas, Chen, Min-Hsuan, Wu, Xiwei, Ribas, Antoni, Badie, Behnam, Forman, Stephen J, Brown, Christine E

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3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T cells von Wang, Zhiqiang, McWilliams-Koeppen, Helen P., Reza, Hernan, Ostberg, Julie R., Chen, Wuyang, Wang, Xiuli, Huynh, Christian, Vyas, Vibhuti, Chang, Wen-Chung, Starr, Renate, Wagner, Jamie R., Aguilar, Brenda, Yang, Xin, Wu, Xiwei, Wang, Jinhui, Chen, Wei, Koelker-Wolfe, Ellery, Seet, Christopher S., Montel-Hagen, Amélie, Crooks, Gay M., Forman, Stephen J., Brown, Christine E.

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