Imbalance Between Xanthine Oxidase and Nitric Oxide Synthase Signaling Pathways Underlies Mechanoenergetic Uncoupling in the Failing Heart von Saavedra, Walter F, Paolocci, Nazareno, St. John, Marcus E, Skaf, Michel W, Stewart, Garrick C, Xie, Jin-Sheng, Harrison, Robert W, Zeichner, Joshua, Mudrick, Daniel, Marbán, Eduardo, Kass, David A, Hare, Joshua M

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Increased levels of uric acid predict haemodynamic compromise in patients with heart failure independently of B-type natriuretic peptide levels von Kittleson, Michelle M, St John, Marcus E, Bead, Valeriani, Champion, Hunter C, Kasper, Edward K, Russell, Stuart D, Wittstein, Ilan S, Hare, Joshua M

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Positive Inotropic and Lusitropic Effects of HNO/NO-in Failing Hearts: Independence from β-Adrenergic Signaling von Paolocci, Nazareno, Katori, Tatsuo, Champion, Hunter C., St. John, Marcus E., Miranda, Katrina M., Fukuto, Jon M., Wink, David A., Kass, David A.

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Elevated Uric Acid Levels Predict Allograft Vasculopathy in Cardiac Transplant Recipients von Kittleson, Michelle M., MD, PhD, Bead, Valeriani, MD, Fradley, Michael, MD, St. John, Marcus E., MD, Champion, Hunter C., MD, PhD, Kasper, Edward K., MD, Russell, Stuart D., MD, Wittstein, Ilan S., MD, Hare, Joshua M., MD

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Intravenous calcium in the treatment of postoperative hypotension von JOHN, Marcus E. St, CHANDRA-STROBOS, Nisha

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Imbalance between xanthine oxidase and nitric oxide synthase signaling pathways underlies mechanoenergetic upcoupling in the failing heart von Saavedra, Walter F, Paolocci, Nazareno, St John, Marcus E, Skaf, Michel W, Tal, E

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Catheter-based percutaneous cellular cardiomyoplasty using allogeneic bone marrow derived mesenchymal stem cells von St. John, Marcus E., Xie, Jinsheng, Heidman, Alan W., Stewart, Garrick C., Cattaneo, Stephen M., Caparrelli, David J., Baumgartner, William A., Martin, Bradley J., Hare, Joshua M.

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Increased levels of uric acid predict haemodynamic compromise in patients with heart failure in ependently of B-type natriuretic peptide levels von KITTLESON, Michelle M, ST JOHN, Marcus E, BEAD, Valeriani, CHAMPION, Hunter C, KASPER, Edward K, RUSSELL, Stuart D, WITTSTEIN, Ilan S, HARE, Joshua M

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FGF23 induces left ventricular hypertrophy von Faul, Christian, Amaral, Ansel P, Oskouei, Behzad, Hu, Ming-Chang, Sloan, Alexis, Isakova, Tamara, Gutiérrez, Orlando M, Aguillon-Prada, Robier, Lincoln, Joy, Hare, Joshua M, Mundel, Peter, Morales, Azorides, Scialla, Julia, Fischer, Michael, Soliman, Elsayed Z, Chen, Jing, Go, Alan S, Rosas, Sylvia E, Nessel, Lisa, Townsend, Raymond R, Feldman, Harold I, St John Sutton, Martin, Ojo, Akinlolu, Gadegbeku, Crystal, Di Marco, Giovana Seno, Reuter, Stefan, Kentrup, Dominik, Tiemann, Klaus, Brand, Marcus, Hill, Joseph A, Moe, Orson W, Kuro-O, Makoto, Kusek, John W, Keane, Martin G, Wolf, Myles

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Mining the human phenome using allelic scores that index biological intermediates von Evans, David M, Brion, Marie Jo A, Paternoster, Lavinia, Kemp, John P, McMahon, George, Munafò, Marcus, Whitfield, John B, Medland, Sarah E, Montgomery, Grant W, Timpson, Nicholas J, St Pourcain, Beate, Lawlor, Debbie A, Martin, Nicholas G, Dehghan, Abbas, Hirschhorn, Joel, Smith, George Davey

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Integrated genomic characterization of oesophageal carcinoma von Reis, R. M., The Cancer Genome Atlas Research Network

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Deregulation of DUX4 and ERG in acute lymphoblastic leukemia von Zhang, Jinghui, McCastlain, Kelly, Yoshihara, Hiroki, Xu, Beisi, Chang, Yunchao, Churchman, Michelle L, Wu, Gang, Li, Yongjin, Wei, Lei, Iacobucci, Ilaria, Liu, Yu, Qu, Chunxu, Wen, Ji, Edmonson, Michael, Payne-Turner, Debbie, Kaufmann, Kerstin B, Takayanagi, Shin-ichiro, Wienholds, Erno, Waanders, Esmé, Ntziachristos, Panagiotis, Bakogianni, Sofia, Wang, Jingjing, Aifantis, Iannis, Roberts, Kathryn G, Ma, Jing, Song, Guangchun, Easton, John, Mulder, Heather L, Chen, Xiang, Newman, Scott, Ma, Xiaotu, Rusch, Michael, Gupta, Pankaj, Boggs, Kristy, Vadodaria, Bhavin, Dalton, James, Liu, Yanling, Valentine, Marcus L, Ding, Li, Lu, Charles, Fulton, Robert S, Fulton, Lucinda, Tabib, Yashodhan, Ochoa, Kerri, Devidas, Meenakshi, Pei, Deqing, Cheng, Cheng, Yang, Jun, Evans, William E, Relling, Mary V, Pui, Ching-Hon, Jeha, Sima, Harvey, Richard C, Chen, I-Ming L, Willman, Cheryl L, Marcucci, Guido, Bloomfield, Clara D, Kohlschmidt, Jessica, Mrózek, Krzysztof, Paietta, Elisabeth, Tallman, Martin S, Stock, Wendy, Foster, Matthew C, Racevskis, Janis, Rowe, Jacob M, Luger, Selina, Kornblau, Steven M, Shurtleff, Sheila A, Raimondi, Susana C, Mardis, Elaine R, Wilson, Richard K, Dick, John E, Hunger, Stephen P, Loh, Mignon L, Downing, James R, Mullighan, Charles G

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The Genomic Landscape of Childhood and Adolescent Melanoma von Lu, Charles, Zhang, Jinghui, Nagahawatte, Panduka, Easton, John, Lee, Seungjae, Liu, Zhifa, Ding, Li, Wyczalkowski, Matthew A., Valentine, Marcus, Navid, Fariba, Mulder, Heather, Tatevossian, Ruth G., Dalton, James, Davenport, James, Yin, Zhirong, Edmonson, Michael, Rusch, Michael, Wu, Gang, Li, Yongjin, Parker, Matthew, Hedlund, Erin, Shurtleff, Sheila, Raimondi, Susana, Bhavin, Vadodaria, Donald, Yergeau, Mardis, Elaine R., Wilson, Richard K., Evans, William E., Ellison, David W., Pounds, Stanley, Dyer, Michael, Downing, James R., Pappo, Alberto, Bahrami, Armita

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Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel von Huang, Jie, Howie, Bryan, McCarthy, Shane, Memari, Yasin, Walter, Klaudia, Min, Josine L., Danecek, Petr, Malerba, Giovanni, Trabetti, Elisabetta, Zheng, Hou-Feng, Gambaro, Giovanni, Richards, J. Brent, Durbin, Richard, Timpson, Nicholas J., Marchini, Jonathan, Soranzo, Nicole

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The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls von de Leeuw, Christiaan A., McQuillin, Andrew, Ripke, Stephan, Trzaskowski, Maciej, Agerbo, Esben, Alliey-Rodriguez, Ney, Andlauer, Till F.M., Awasthi, Swapnil, Badner, Judith A., Bækvad-Hansen, Marie, Bøen, Erlend, Castelao, Enrique, Cerrato, Felecia, Cervantes, Pablo, Colodro-Conde, Lucía, Davies, Gail, Del-Favero, Jurgen, Dumont, Ashley, Fischer, Sascha B., Foo, Jerome C., Forty, Liz, Gordon, Scott D., Green, Melissa J., Grove, Jakob, Hansen, Christine Søholm, Hansen, Thomas F., Heilbronner, Urs, van Hemert, Albert M., Hipolito, Maria, Hoffmann, Per, Holland, Dominic, Jamain, Stéphane, Jansen, Rick, Johnson, Jessica S., de Jong, Simone, Hassan Kiadeh, Farnush Farhadi, Kraft, Julia, Krogh, Jesper, Lawson, William B., Li, Yihan, Maaser, Anna, MacKinnon, Dean F., Mahon, Pamela B., Maier, Robert M., Medland, Sarah E., Mehta, Divya, Mihailov, Evelin, Montgomery, Grant W., Mullins, Niamh, Nyholt, Dale R., Ösby, Urban, Peterson, Roseann E., Pistis, Giorgio, Reinbold, Céline S., Ryu, Euijung, Schoevers, Robert, Schork, Nicholas J., Schulte, Eva C., Shehktman, Tatyana, Streit, Fabian, Thompson, Robert C., Traylor, Matthew, Vedder, Helmut, Viktorin, Alexander, Visscher, Peter M., Watson, Stanley J., Weinsheimer, Shantel Marie, Wu, Yang, Zhang, Peng, Agartz, Ingrid, Backlund, Lena, Bellivier, Frank, Blackwood, Douglas H.R., Domenici, Enrico, Fullerton, Janice M., Goes, Fernando, Hayward, Caroline, Hultman, Christina M., Jones, Ian, Kahn, René S., Kloiber, Stefan, Leboyer, Marion, Li, Qingqin S., Lucae, Susanne, Madden, Pamela A.F., Magnusson, Patrik K., Martin, Nicholas G., Mortensen, Preben Bo, Neale, Benjamin M., Nordentoft, Merete, O'Donovan, Michael C., Pato, Carlos, Pato, Michele T., Penninx, Brenda W.J. H., Posthuma, Danielle, Stefansson, Kari, Vieta, Eduard, Di Florio, Arianna, Ophoff, Roel A., Wray, Naomi R.

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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls von Clayton, David G, Cardon, Lon R, Duncanson, Audrey, Ouwehand, Willem H, Todd, John A, Donnelly, Peter, Easton, Doug, Evans, David, Morris, Andrew P, Spencer, Chris C. A, Boorman, James P, Cant, Barbara, Everson, Ursula, Hussey, Judith M, Knight, Alexandra S, Nutland, Sarah, Stevens, Helen E, Watkins, Nicholas A, Jones, Richard W, Ring, Susan M, Breen, Gerome, Caesar, Sian, Green, Elaine K, Grozeva, Detelina, Jones, Ian R, Kirov, George, Moskvina, Valentina, Nikolov, Ivan, Collier, David A, Farmer, Anne, Williamson, Richard, Young, Allan H, Ball, Stephen G, Balmforth, Anthony J, Bishop, D. Timothy, Iles, Mark M, Dixon, Richard J, Stevens, Suzanne, Thompson, John R, Bredin, Francesca, Tremelling, Mark, Drummond, Hazel, Nimmo, Elaine R, Fisher, Sheila A, Forbes, Alastair, Lewis, Cathryn M, Prescott, Natalie J, Barbour, Jamie, Mohiuddin, M. Khalid, Mansfield, John C, Cummings, Fraser R, Connell, John, Dobson, Richard, Gungadoo, Johannie, Newhouse, Stephen J, Barton, Anne, Bruce, Ian N, John, Sally L, Potter, Catherine, Silman, Alan J, Symmons, Deborah P. M, Dunger, David B, Widmer, Barry, Frayling, Timothy M, Lango, Hana, Perry, John R. B, Groves, Christopher J, Rayner, Nigel W, Timpson, Nicholas J, Zeggini, Eleftheria, Newport, Melanie, Vannberg, Fredrik, Farrar, Claire, Wordsworth, Paul, Brown, Matthew A, Franklyn, Jayne A, Heward, Joanne M, Simmonds, Matthew J, Seal, Sheila, Stratton, Michael R, Ban, Maria, Conway, David, Chaney, Amy, Ghori, Mohammed J. R, Gwilliam, Rhian, Hunt, Sarah E, McGinnis, Ralph, Potter, Simon, Whittaker, Pamela, Widden, Claire, Withers, David, Hallgrimsdottir, Ingileif B, Vukcevic, Damjan, Bentley, David, Caulfield, Mark, Compston, Alistair, Farrall, Martin, Hall, Alistair S, Hattersley, Andrew T, Mathew, Christopher G

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Genome-wide and fine-resolution association analysis of malaria in West Africa von Jallow, Muminatou, Molyneux, Malcolm E, Singhasivanon, Pratap, Clark, Taane G, Donnelly, Peter, Parker, Michael, Mueller, Ivo, Pinder, Margaret, Karunaweera, Nadira, Dolo, Amagana, Fry, Andrew E, Gwilliam, Rhian, Bojang, Kalifa A, Williams, Thomas N, Amodu, Olukemi, Horstmann, Rolf D, Kokwaro, Gilbert, Rowlands, Kate, Drakeley, Chris, Auburn, Sarah, Bumpstead, Suzannah J, Doumbo, Ogobara K, Achidi, Eric Akum, Agbenyega, Tsiri, Peshu, Norbert, Somaskantharajah, Elilan, Mendy, Alieu, Marchini, Jonathan, Dunstan, Sarah, Lemnge, Martha, Teo, Yik Ying, Tall, Adama, Ibrahim, Muntaser, Deloukas, Panos, Makani, Julie, Rockett, Kirk A, Green, Angela, Jeffreys, Anna E, Sirima, Sodiomon, Koram, Kwadwo A, Campino, Susana, Morris, Andrew, Corran, Patrick, Modiano, David, Sisay-Joof, Fatou, Troye-Blomberg, Marita, Potter, Simon, Fernando, Deepika, Riley, Eleanor M, Evans, Jennifer, Sakuntabhai, Anavaj, Conway, David J, Widden, Claire, Ragoussis, Jiannis, Allen, Angela, Inouye, Michael, Hien, Tran Tinh, Palotie, Aarno, Sirugo, Giorgio, Taylor, Terrie E, Howie, Bryan, Kwiatkowski, Dominic P, Thera, Mahamadou, Kivinen, Katja, Small, Kerrin S, Puijalon, Odile, Hunt, Sarah E, Djimde, Abdoulaye, Farrar, Jeremy, Marsh, Kevin, Michon, Pascal, Reyburn, Hugh, Usen, Stanley, Wilson, Michael, Coffey, Alison, SanJoaquin, Miguel, Plowe, Christopher V, Dunham, Andrew, Rogers, Jane, Reeder, John, Whittaker, Pamela

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MultiSero: An Open-Source Multiplex-ELISA Platform for Measuring Antibody Responses to Infection von Byrum, Janie R, Waltari, Eric, Janson, Owen, Guo, Syuan-Ming, Folkesson, Jenny, Chhun, Bryant B, Vinden, Joanna, Ivanov, Ivan E, Forst, Marcus L, Li, Hongquan, Larson, Adam G, Blackmon, Lena, Liu, Ziwen, Wu, Wesley, Ahyong, Vida, Tato, Cristina M, McCutcheon, Krista M, Hoh, Rebecca, Kelly, J Daniel, Martin, Jeffrey N, Peluso, Michael J, Henrich, Timothy J, Deeks, Steven G, Prakash, Manu, Greenhouse, Bryan, Mehta, Shalin B, Pak, John E

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Genome-wide association study identifies eight loci associated with blood pressure von Jackson, Anne U, Burton, Paul R, Di Gregorio, Alessandra, Mohlke, Karen L, Galan, Pilar, Syvänen, Ann-Christine, Marrugat, Jaume, Jarvelin, Marjo-Riitta, Newton-Cheh, Christopher, Meitinger, Thomas, Watkins, Hugh, Lucas, Gavin, Soranzo, Nicole, Tobin, Martin D, Wain, Louise V, Kooner, Jaspal S, Wallace, Chris, Altshuler, David, Najjar, Samer S, Zeggini, Eleftheria, Felix, Stephan B, Freimer, Nelson B, Laakso, Markku, Homuth, Georg, Ferrucci, Luigi, Brown, Morris, Snieder, Harold, Wichmann, H Erich, Orho-Melander, Marju, Chambers, John C, Valle, Timo T, van der Schouw, Yvonne T, Ernst, Florian, Strachan, David P, van der Harst, Pim, Kathiresan, Sekar, Romanazzi, Valeria, Dörr, Marcus, McArdle, Wendy L, Peden, John F, Beckmann, Jacques S, Song, Kijoung, Yuan, Xin, Melander, Olle, Coin, Lachlan, Lim, Noha, Barroso, Inês, Eyheramendy, Susana, O'Reilly, Paul F, Salomaa, Veikko, Gut, Ivo G, Tuomilehto, Jaakko, Peltonen, Leena, Morken, Mario A, Org, Elin, Luan, Jian'an, Panico, Salvatore, de Jong, Paul E, Schwartz, Stephen M, Matullo, Giuseppe, Wareham, Nicholas J, Seedorf, Udo, Laan, Maris, Uiterwaal, Cuno S, Boehnke, Michael, Farrall, Martin, Elosua, Roberto, Webster, John, Vollenweider, Peter, Reffelmann, Thorsten, Abecasis, Gonçalo R, Rettig, Rainer, Zhao, Jing Hua, Khaw, Kay-Tee, Elliott, Katherine S, Forouhi, Nita G, Voight, Benjamin F, Caulfield, Mark, Dominiczak, Anna, Munroe, Patricia B, Zhai, Guangju, Loos, Ruth JF, Sacerdote, Carlotta, Mooser, Vincent, Bergmann, Sven, Lakatta, Edward G, Bingham, Sheila A, Numans, Mattijs E, Völker, Uwe, Stringham, Heather M, Jousilahti, Pekka, Williams, Frances M, Clarke, Robert, Allione, Alessandra, Spector, Tim D, Elliott, Paul, Collins, Francis S, Lorbeer, Roberto, Sanna, Serena, Ricceri, Fulvio

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Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality von Schunk, Stefan J, Kleber, Marcus E, März, Winfried, Pang, Shichao, Zewinger, Stephen, Triem, Sarah, Ege, Philipp, Reichert, Matthias C, Krawczyk, Marcin, Weber, Susanne N, Jaumann, Isabella, Schmit, David, Sarakpi, Tamim, Wagenpfeil, Stefan, Kramann, Rafael, Boerwinkle, Eric, Ballantyne, Christie M, Grove, Megan L, Tragante, Vinicius, Pilbrow, Anna P, Richards, A Mark, Cameron, Vicky A, Doughty, Robert N, Dubé, Marie-Pierre, Tardif, Jean-Claude, Feroz-Zada, Yassamin, Sun, Maxine, Liu, Chang, Ko, Yi-An, Quyyumi, Arshed A, Hartiala, Jaana A, Tang, W H Wilson, Hazen, Stanley L, Allayee, Hooman, McDonough, Caitrin W, Gong, Yan, Cooper-DeHoff, Rhonda M, Johnson, Julie A, Scholz, Markus, Teren, Andrej, Burkhardt, Ralph, Martinsson, Andreas, Smith, J Gustav, Wallentin, Lars, James, Stefan K, Eriksson, Niclas, White, Harvey, Held, Claes, Waterworth, Dawn, Trompet, Stella, Jukema, J Wouter, Ford, Ian, Stott, David J, Sattar, Naveed, Cresci, Sharon, Spertus, John A, Campbell, Hannah, Tierling, Sascha, Walter, Jörn, Ampofo, Emmanuel, Niemeyer, Barbara A, Lipp, Peter, Schunkert, Heribert, Böhm, Michael, Koenig, Wolfgang, Fliser, Danilo, Laufs, Ulrich, Speer, Thimoteus

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