Remodeling of active endothelial enhancers is associated with aberrant gene-regulatory networks in pulmonary arterial hypertension von Reyes-Palomares, Armando, Gu, Mingxia, Grubert, Fabian, Berest, Ivan, Sa, Silin, Kasowski, Maya, Arnold, Christian, Shuai, Mao, Srivas, Rohith, Miao, Simon, Li, Dan, Snyder, Michael P., Rabinovitch, Marlene, Zaugg, Judith B.

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Landscape of cohesin-mediated chromatin loops in the human genome von Grubert, Fabian, Srivas, Rohith, Spacek, Damek  V, Kasowski, Maya, Ruiz-Velasco, Mariana, Sinnott-Armstrong, Nasa, Greenside, Peyton, Narasimha, Anil, Liu, Qing, Geller, Benjamin, Sanghi, Akshay, Kulik, Michael, Sa, Silin, Rabinovitch, Marlene, Kundaje, Anshul, Dalton, Stephen, Zaugg, Judith B., Snyder, Michael

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Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions von Grubert, Fabian, Zaugg, Judith B., Kasowski, Maya, Ursu, Oana, Spacek, Damek V., Martin, Alicia R., Greenside, Peyton, Srivas, Rohith, Phanstiel, Doug H., Pekowska, Aleksandra, Heidari, Nastaran, Euskirchen, Ghia, Huber, Wolfgang, Pritchard, Jonathan K., Bustamante, Carlos D., Steinmetz, Lars M., Kundaje, Anshul, Snyder, Michael

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Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis von Ang, Yen-Sin, Rivas, Renee N., Ribeiro, Alexandre J.S., Srivas, Rohith, Rivera, Janell, Stone, Nicole R., Pratt, Karishma, Mohamed, Tamer M.A., Fu, Ji-Dong, Spencer, C. Ian, Tippens, Nathaniel D., Li, Molong, Narasimha, Anil, Radzinsky, Ethan, Moon-Grady, Anita J., Yu, Haiyuan, Pruitt, Beth L., Snyder, Michael P., Srivastava, Deepak

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Global reconstruction of the human metabolic network based on genomic and bibliomic data von Duarte, Natalie C, Becker, Scott A, Jamshidi, Neema, Thiele, Ines, Mo, Monica L, Vo, Thuy D, Srivas, Rohith, Palsson, Bernhard Ø

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Dissection of DNA Damage Responses Using Multiconditional Genetic Interaction Maps von Guénolé, Aude, Srivas, Rohith, Vreeken, Kees, Wang, Ze Zhong, Wang, Shuyi, Krogan, Nevan J., Ideker, Trey, van Attikum, Haico

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Attenuated IL-2 muteins leverage the TCR signal to enhance regulatory T cell homeostasis and response in vivo von Ma, Shining, So, Michelle, Ghelani, Aazam, Srivas, Rohith, Sahoo, Anupama, Hall, Robyn, Liu, Wenjun, Wu, Hao, Yu, Sherman, Lu, Shiping, Song, Elly, Cariaga, Taryn, Soto, Marcus, Zhou, Hong, Li, Chi-Ming, Chaudhry, Ashutosh, Luo, Xin, Sohn, Sue J.

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Genome-wide association data reveal a global map of genetic interactions among protein complexes von Hannum, Gregory, Srivas, Rohith, Guénolé, Aude, van Attikum, Haico, Krogan, Nevan J, Karp, Richard M, Ideker, Trey

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A UV-Induced Genetic Network Links the RSC Complex to Nucleotide Excision Repair and Shows Dose-Dependent Rewiring von Srivas, Rohith, Costelloe, Thomas, Carvunis, Anne-Ruxandra, Sarkar, Sovan, Malta, Erik, Sun, Su Ming, Pool, Marijke, Licon, Katherine, van Welsem, Tibor, van Leeuwen, Fred, McHugh, Peter J., van Attikum, Haico, Ideker, Trey

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Expanded encyclopaedias of DNA elements in the human and mouse genomes von Moore, Jill E., Purcaro, Michael J., Pratt, Henry E., Epstein, Charles B., Shoresh, Noam, Adrian, Jessika, Kawli, Trupti, Davis, Carrie A., Dobin, Alexander, Kaul, Rajinder, Halow, Jessica, Van Nostrand, Eric L., Freese, Peter, Gorkin, David U., Shen, Yin, He, Yupeng, Mackiewicz, Mark, Pauli-Behn, Florencia, Williams, Brian A., Mortazavi, Ali, Keller, Cheryl A., Zhang, Xiao-Ou, Elhajjajy, Shaimae I., Huey, Jack, Dickel, Diane E., Snetkova, Valentina, Wei, Xintao, Wang, Xiaofeng, Rivera-Mulia, Juan Carlos, Rozowsky, Joel, Zhang, Jing, Chhetri, Surya B., Zhang, Jialing, Victorsen, Alec, White, Kevin P., Visel, Axel, Yeo, Gene W., Burge, Christopher B., Lécuyer, Eric, Gilbert, David M., Dekker, Job, Rinn, John, Mendenhall, Eric M., Ecker, Joseph R., Kellis, Manolis, Klein, Robert J., Noble, William S., Kundaje, Anshul, Guigó, Roderic, Farnham, Peggy J., Cherry, J. Michael, Myers, Richard M., Ren, Bing, Graveley, Brenton R., Gerstein, Mark B., Pennacchio, Len A., Snyder, Michael P., Bernstein, Bradley E., Wold, Barbara, Hardison, Ross C., Gingeras, Thomas R., Stamatoyannopoulos, John A., Weng, Zhiping

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A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy von Srivas, Rohith, Shen, John Paul, Yang, Chih Cheng, Sun, Su Ming, Li, Jianfeng, Gross, Andrew M., Jensen, James, Licon, Katherine, Bojorquez-Gomez, Ana, Klepper, Kristin, Huang, Justin, Pekin, Daniel, Xu, Jia L., Yeerna, Huwate, Sivaganesh, Vignesh, Kollenstart, Leonie, van Attikum, Haico, Aza-Blanc, Pedro, Sobol, Robert W., Ideker, Trey

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Abstract P5-01-13: Longitudinal changes in whole-genome (WG) cell-free DNA (cfDNA) and methylation as a blood-based biomarker to identify early disease progression in advanced brea... von Davis, Andrew A, Chan, David, Oh, Michael S, Lentz, Robert W, Peterman, Neil, Robertson, Alex, Srivas, Rohith, Shah, Abhik, Lambert, Nicole, Tezcan, Ayse, Tezcan, Haluk, Chae, Young Kwang

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Abstract 6083: Extensive epigenetic and transcriptomic donor-specific differences observed in iPSC derived allogenic NK (iNK) cells von Srivas, Rohith, Nariya, Snehal, Rojsza, Melissa, Morse, Barry A., Manor, Ohad, Amin, Rupesh, Borges, Luis

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Translation of Genotype to Phenotype by a Hierarchy of Cell Subsystems von Yu, Michael Ku, Kramer, Michael, Dutkowski, Janusz, Srivas, Rohith, Licon, Katherine, Kreisberg, Jason F., Ng, Cherie T., Krogan, Nevan, Sharan, Roded, Ideker, Trey

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Early Assessment of Molecular Progression and Response by Whole-genome Circulating Tumor DNA in Advanced Solid Tumors von Davis, Andrew A, Iams, Wade T, Chan, David, Oh, Michael S, Lentz, Robert W, Peterman, Neil, Robertson, Alex, Shah, Abhik, Srivas, Rohith, Wilson, Timothy J, Lambert, Nicole J, George, Peter S, Wong, Becky, Wood, Haleigh W, Close, Jason C, Tezcan, Ayse, Nesmith, Ken, Tezcan, Haluk, Chae, Young Kwang

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Yeast PP4 Interacts with ATR Homolog Ddc2-Mec1 and Regulates Checkpoint Signaling von Hustedt, Nicole, Seeber, Andrew, Sack, Ragna, Tsai-Pflugfelder, Monika, Bhullar, Bhupinder, Vlaming, Hanneke, van Leeuwen, Fred, Guénolé, Aude, van Attikum, Haico, Srivas, Rohith, Ideker, Trey, Shimada, Kenji, Gasser, Susan M.

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Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism von van Welsem, Tibor, Korthout, Tessy, Ekkebus, Reggy, Morais, Dominique, Molenaar, Thom M, van Harten, Kirsten, Poramba-Liyanage, Deepani W, Sun, Su Ming, Lenstra, Tineke L, Srivas, Rohith, Ideker, Trey, Holstege, Frank C P, van Attikum, Haico, El Oualid, Farid, Ovaa, Huib, Stulemeijer, Iris J E, Vlaming, Hanneke, van Leeuwen, Fred

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Abstract 2279: Serial changes in tumor-derived whole-genome cfDNA fraction to identify early disease progression prior to imaging von Davis, Andrew A., Iams, Wade T., Chan, David, Oh, Michael S., Lentz, Robert W., Peterman, Neil, Robertson, Alex, Shah, Abhik, Srivas, Rohith, Lambert, Nicole, Wilson, Tim, George, Peter, Wong, Becky, Tezcan, Ayse, Yalamanchili, Ram, Nesmith, Ken, Spinosa, John C., Tezcan, Haluk, Chae, Young Kwang

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A prospective study tracking longitudinal changes in genome-wide cell-free DNA (cfDNA) methylation to identify early nonresponders to cancer treatment von Davis, Andrew A., Iams, Wade Thomas, Chan, David, Oh, Michael S, Lentz, Robert William, Srivas, Rohith, Lambert, Nicole, Robertson, Alex, Peterman, Neil, Shah, Abhik, Wilson, Timothy, Close, Jason, George, Peter, Wood, Haleigh, Tezcan, Ayse, Yalamanchili, Ram, Nesmith, Ken, Spinosa, John C, Tezcan, Haluk, Chae, Young Kwang

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Whole-genome cell-free DNA (cfDNA) changes as a dynamic blood-based biomarker for early response assessment of advanced tumors von Davis, Andrew A., Iams, Wade Thomas, Chan, David, Oh, Michael S, Lentz, Robert William, Peterman, Neil, Robertson, Alex, Shah, Abhik, Srivas, Rohith, Lambert, Nicole, Wilson, Timothy, George, Peter, Wong, Becky, Tezcan, Ayse, Yalamanchili, Ram, Nesmith, Ken, Spinosa, John C, Tezcan, Haluk, Chae, Young Kwang

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