Modern vitiligo genetics sheds new light on an ancient disease von Spritz, Richard A.

Volltext

Precise modulation of transcription factor levels identifies features underlying dosage sensitivity von Naqvi, Sahin, Kim, Seungsoo, Hoskens, Hanne, Matthews, Harold S., Spritz, Richard A., Klein, Ophir D., Hallgrímsson, Benedikt, Swigut, Tomek, Claes, Peter, Pritchard, Jonathan K., Wysocka, Joanna

Volltext

Shared Genetic Relationships Underlying Generalized Vitiligo and Autoimmune Thyroid Disease von Spritz, Richard A.

Volltext

The genetic architecture of vitiligo von Roberts, Genevieve H. L., Santorico, Stephanie A., Spritz, Richard A.

Volltext

NLRP1 haplotypes associated with vitiligo and autoimmunity increase interleukin-1β processing via the NLRP1 inflammasome von Levandowski, Cecilia B., Mailloux, Christina M., Ferrara, Tracey M., Gowan, Katherine, Ben, Songtao, Jin, Ying, McFann, Kimberly K., Holland, Paulene J., Fain, Pamela R., Dinarello, Charles A., Spritz, Richard A.

Volltext

Genomewide Association Study of African Children Identifies Association of SCHIP1 and PDE8A with Facial Size and Shape von Cole, Joanne B, Manyama, Mange, Kimwaga, Emmanuel, Mathayo, Joshua, Larson, Jacinda R, Liberton, Denise K, Lukowiak, Ken, Ferrara, Tracey M, Riccardi, Sheri L, Li, Mao, Mio, Washington, Prochazkova, Michaela, Williams, Trevor, Li, Hong, Jones, Kenneth L, Klein, Ophir D, Santorico, Stephanie A, Hallgrimsson, Benedikt, Spritz, Richard A

Volltext

MHC class II super-enhancer increases surface expression of HLA-DR and HLA-DQ and affects cytokine production in autoimmune vitiligo von Cavalli, Giulio, Hayashi, Masahiro, Jin, Ying, Yorgov, Daniel, Santorico, Stephanie A., Holcomb, Cherie, Rastrou, Melinda, Erlich, Henry, Tengesdal, Isak W., Dagna, Lorenzo, Neff, C. Preston, Palmer, Brent E., Spritz, Richard A., Dinarello, Charles A.

Volltext

A Melanoma Brain Metastasis with a Donor-Patient Hybrid Genome following Bone Marrow Transplantation: First Evidence for Fusion in Human Cancer von Lazova, Rossitza, Laberge, Greggory S, Duvall, Eric, Spoelstra, Nicole, Klump, Vincent, Sznol, Mario, Cooper, Dennis, Spritz, Richard A, Chang, Joseph T, Pawelek, John M

Volltext

Early-onset autoimmune vitiligo associated with an enhancer variant haplotype that upregulates class II HLA expression von Jin, Ying, Roberts, Genevieve H. L., Ferrara, Tracey M., Ben, Songtao, van Geel, Nanja, Wolkerstorfer, Albert, Ezzedine, Khaled, Siebert, Janet, Neff, Charles P., Palmer, Brent E., Santorico, Stephanie A., Spritz, Richard A.

Volltext

Large-scale open-source three-dimensional growth curves for clinical facial assessment and objective description of facial dysmorphism von Matthews, Harold S., Palmer, Richard L., Baynam, Gareth S., Quarrell, Oliver W., Klein, Ophir D., Spritz, Richard A., Hennekam, Raoul C., Walsh, Susan, Shriver, Mark, Weinberg, Seth M., Hallgrimsson, Benedikt, Hammond, Peter, Penington, Anthony J., Peeters, Hilde, Claes, Peter D.

Volltext

Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations von Liu, Chenxing, Lee, Myoung Keun, Naqvi, Sahin, Hoskens, Hanne, Liu, Dongjing, White, Julie D., Indencleef, Karlijne, Matthews, Harold, Eller, Ryan J., Li, Jiarui, Mohammed, Jaaved, Swigut, Tomek, Richmond, Stephen, Manyama, Mange, Hallgrimsson, Benedikt, Spritz, Richard A., Feingold, Eleanor, Marazita, Mary L., Wysocka, Joanna, Walsh, Susan, Shriver, Mark D., Claes, Peter, Weinberg, Seth M., Shaffer, John R.

Volltext

Autoimmune vitiligo is associated with gain-of-function by a transcriptional regulator that elevates expression of HLA-A02:01 in vivo von Hayashi, Masahiro, Jin, Ying, Yorgov, Daniel, Santorico, Stephanie A., Hagman, James, Ferrara, Tracey M., Jones, Kenneth L., Cavalli, Giulio, Dinarello, Charles A., Spritz, Richard A.

Volltext

Recent progress in the genetics of generalized vitiligo von Spritz, Richard A.

Volltext

Fully Automatic Landmarking of Syndromic 3D Facial Surface Scans Using 2D Images von Bannister, Jordan J., Crites, Sebastian R., Aponte, J. David, Katz, David C., Wilms, Matthias, Klein, Ophir D., Bernier, Francois P. J., Spritz, Richard A., Hallgrimsson, Benedikt, Forkert, Nils D.

Volltext

Multiple Functional Variants of IFIH1, a Gene Involved in Triggering Innate Immune Responses, Protect against Vitiligo von Jin, Ying, Andersen, Genevieve H.L., Santorico, Stephanie A., Spritz, Richard A.

Volltext

Six Decades of Vitiligo Genetics: Genome-Wide Studies Provide Insights into Autoimmune Pathogenesis von Spritz, Richard A.

Volltext

The genetics of generalized vitiligo and associated autoimmune diseases von Spritz, Richard A.

Volltext

The Genetic Basis of Vitiligo von Spritz, Richard A., Santorico, Stephanie A.

Volltext

Spatial and temporal analysis of gene expression during growth and fusion of the mouse facial prominences von Feng, Weiguo, Leach, Sonia M, Tipney, Hannah, Phang, Tzulip, Geraci, Mark, Spritz, Richard A, Hunter, Lawrence E, Williams, Trevor

Volltext

Comprehensive Association Analysis of Candidate Genes for Generalized Vitiligo Supports XBP1, FOXP3, and TSLP von Birlea, Stanca A., Jin, Ying, Bennett, Dorothy C., Herbstman, Deborah M., Wallace, Margaret R., McCormack, Wayne T., Helen Kemp, E., Gawkrodger, David J., Weetman, Anthony P., Picardo, Mauro, Leone, Giovanni, Taïeb, Alain, Jouary, Thomas, Ezzedine, Khaled, van Geel, Nanja, Lambert, Jo, Overbeck, Andreas, Fain, Pamela R., Spritz, Richard A.

Volltext