Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles von Syed, Abdullah M., Ciling, Alison, Taha, Taha Y., Chen, Irene P., Khalid, Mir M., Sreekumar, Bharath, Chen, Pei-Yi, Kumar, G. Renuka, Suryawanshi, Rahul, Silva, Ines, Milbes, Bilal, Kojima, Noah, Hess, Victoria, Shacreaw, Maria, Lopez, Lauren, Brobeck, Matthew, Turner, Fred, Spraggon, Lee, Tabata, Takako, Ott, Melanie, Doudna, Jennifer A.

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In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA von La Rocca, Gaspare, Olejniczak, Scott H., González, Alvaro J., Briskin, Daniel, Vidigal, Joana A., Spraggon, Lee, DeMatteo, Raymond G., Radler, Megan R., Lindsten, Tullia, Ventura, Andrea, Tuschl, Thomas, Leslie, Christina S., Thompson, Craig B.

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Non-cell-autonomous retinoid signaling is crucial for renal development von Rosselot, Carolina, Spraggon, Lee, Chia, Ian, Batourina, Ekatherina, Riccio, Paul, Lu, Benson, Niederreither, Karen, Dolle, Pascal, Duester, Gregg, Chambon, Pierre, Costantini, Frank, Gilbert, Thierry, Molotkov, Andrei, Mendelsohn, Cathy

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A Wt1-Controlled Chromatin Switching Mechanism Underpins Tissue-Specific Wnt4 Activation and Repression von Essafi, Abdelkader, Webb, Anna, Berry, Rachel L., Slight, Joan, Burn, Sally F., Spraggon, Lee, Velecela, Victor, Martinez-Estrada, Ofelia M., Wiltshire, John H., Roberts, Stefan G.E., Brownstein, David, Davies, Jamie A., Hastie, Nicholas D., Hohenstein, Peter

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Novel patient-derived models of desmoplastic small round cell tumor confirm a targetable dependency on ERBB signaling von Smith, Roger S, Odintsov, Igor, Liu, Zebing, Lui, Allan Jo-Weng, Hayashi, Takuo, Vojnic, Morana, Suehara, Yoshiyuki, Delasos, Lukas, Mattar, Marissa S, Hmeljak, Julija, Ramirez, Hillary A, Shaw, Melissa, Bui, Gabrielle, Hartono, Alifiani B, Gladstone, Eric, Kunte, Siddharth, Magnan, Heather, Khodos, Inna, De Stanchina, Elisa, La Quaglia, Michael P, Yao, Jinjuan, Laé, Marick, Lee, Sean B, Spraggon, Lee, Pratilas, Christine A, Ladanyi, Marc, Somwar, Romel

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Generation of conditional oncogenic chromosomal translocations using CRISPR–Cas9 genomic editing and homology‐directed repair von Spraggon, Lee, Martelotto, Luciano G, Hmeljak, Julija, Hitchman, Tyler D, Wang, Jiang, Wang, Lu, Slotkin, Emily K, Fan, Pang‐Dian, Reis‐Filho, Jorge S, Ladanyi, Marc

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Stromal protein Ecm1 regulates ureteric bud patterning and branching von Paroly, Suneeta S, Wang, Fengwei, Spraggon, Lee, Merregaert, Joseph, Batourina, Ekatherina, Tycko, Benjamin, Schmidt-Ott, Kai M, Grimmond, Sean, Little, Melissa, Mendelsohn, Cathy

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U1 snRNP-Dependent Suppression of Polyadenylation: Physiological Role and Therapeutic Opportunities in Cancer von Spraggon, Lee, Cartegni, Luca

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Salt-Inducible Kinase 1 is a potential therapeutic target in Desmoplastic Small Round Cell Tumor von Hartono, Alifiani Bonita, Kang, Hong-Jun, Shi, Lawrence, Phipps, Whitney, Ungerleider, Nathan, Giardina, Alexandra, Chen, WeiPing, Spraggon, Lee, Somwar, Romel, Moroz, Krzysztof, Drewry, David H., Burow, Matthew E., Flemington, Erik, Ladanyi, Marc, Lee, Sean Bong

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Previous exposure to Spike-providing parental strains confers neutralizing immunity to XBB lineage and other SARS-CoV-2 recombinants in the context of vaccination von Suryawanshi, Rahul K, Taha, Taha Y, McCavitt-Malvido, Maria, Silva, Ines, Khalid, Mir M, Syed, Abdullah M, Chen, Irene P, Saldhi, Prachi, Sreekumar, Bharath, Montano, Mauricio, Foresythe, Kafaya, Tabata, Takako, Kumar, G Renuka, Sotomayor-Gonzalez, Alicia, Servellita, Venice, Gliwa, Amelia, Nguyen, Jenny, Kojima, Noah, Arellanor, Teresa, Bussanich, Aallyah, Hess, Victoria, Shacreaw, Maria, Lopez, Lauren, Brobeck, Matthew, Turner, Fred, Wang, Yuzhu, Ghazarian, Sydney, Davis, Gregg, Rodriguez, Diviana, Doudna, Jennifer, Spraggon, Lee, Chiu, Charles Y, Ott, Melanie

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Antisense modulation of RNA processing as a therapeutic approach in cancer therapy von Spraggon, Lee, Cartegni, Luca

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Abstract LB-318: Reshaping the cancer proteome: therapeutic targeting of signaling and resistance in cancer by antisense manipulation of RNA processing von Cartegni, Luca, Spraggon, lee

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Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination von Suryawanshi, Rahul K., Chen, Irene P., Ma, Tongcui, Syed, Abdullah M., Brazer, Noah, Saldhi, Prachi, Simoneau, Camille R., Ciling, Alison, Khalid, Mir M., Sreekumar, Bharath, Chen, Pei-Yi, Kumar, G. Renuka, Montano, Mauricio, Gascon, Ronne, Tsou, Chia-Lin, Garcia-Knight, Miguel A., Sotomayor-Gonzalez, Alicia, Servellita, Venice, Gliwa, Amelia, Nguyen, Jenny, Silva, Ines, Milbes, Bilal, Kojima, Noah, Hess, Victoria, Shacreaw, Maria, Lopez, Lauren, Brobeck, Matthew, Turner, Fred, Soveg, Frank W., George, Ashley F., Fang, Xiaohui, Maishan, Mazharul, Matthay, Michael, Morris, Mary Kate, Wadford, Debra, Hanson, Carl, Greene, Warner C., Andino, Raul, Spraggon, Lee, Roan, Nadia R., Chiu, Charles Y., Doudna, Jennifer A., Ott, Melanie

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Abstract LB-239: Induction of therapeutic soluble decoy EGFR variants by antisense manipulation of RNA processing von Park, Jeong Eun, Spraggon, Lee, Cartegni, Luca

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Abstract 1836: Induction of secreted soluble decoy EGFR variants by splicing interference overcomes drug resistance in human non-small cell lung cancer von Park, Jeong Eun, Spraggon, Lee, Stanchina, Elisa de, Cartegni, Luca

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Whole-genome single-cell copy number profiling from formalin-fixed paraffin-embedded samples von Martelotto, Luciano G, Baslan, Timour, Kendall, Jude, Geyer, Felipe C, Burke, Kathleen A, Spraggon, Lee, Piscuoglio, Salvatore, Chadalavada, Kalyani, Nanjangud, Gouri, Ng, Charlotte K Y, Moody, Pamela, D'Italia, Sean, Rodgers, Linda, Cox, Hilary, da Cruz Paula, Arnaud, Stepansky, Asya, Schizas, Michail, Wen, Hannah Y, King, Tari A, Norton, Larry, Weigelt, Britta, Hicks, James B, Reis-Filho, Jorge S

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Therapeutic Potential of NTRK3 Inhibition in Desmoplastic Small Round Cell Tumor von Ogura, Koichi, Somwar, Romel, Hmeljak, Julija, Magnan, Heather, Benayed, Ryma, Boroujeni, Amir Momeni, Bowman, Anita S., Mattar, Marissa S., Khodos, Inna, de Stanchina, Elisa, Jungbluth, Achim, Asher, Marina, Odintsov, Igor, Hartono, Alifiani B., LaQuaglia, Michael P., Slotkin, Emily, Pratilas, Christine A., Lee, Sean Bong, Spraggon, Lee, Ladanyi, Marc

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YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics von Fan, Pang-Dian, Narzisi, Giuseppe, Jayaprakash, Anitha D., Venturini, Elisa, Robine, Nicolas, Smibert, Peter, Germer, Soren, Yu, Helena A., Jordan, Emmet J., Paik, Paul K., Janjigian, Yelena Y., Chaft, Jamie E., Wang, Lu, Jungbluth, Achim A., Middha, Sumit, Spraggon, Lee, Qiao, Huan, Lovly, Christine M., Kris, Mark G., Riely, Gregory J., Politi, Katerina, Varmus, Harold, Ladanyi, Marc

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Abstract B12: Therapeutic potential of NTRK3 in desmoplastic small round cell tumor von Spraggon, Lee, Hmeljak, Julija, Magnan, Heather, Somwar, Romel, Asher, Marina, Hartono, Alifiani B., Lee, Sean Bong, Ladanyi, Marc

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Abstract LB-031: Generation of inducible oncogenic chromosomal translocations using CRISPR-Cas9 genomic editing von Spraggon, Lee, Martelotto, Luciano, Hmeljak, Julija, Slotkin, Emily, Wang, Lu, Reis-Filho, Jorge, Ladanyi, Marc

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