The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1 von Chantranupong, Lynne, Wolfson, Rachel L, Orozco, Jose M, Saxton, Robert A, Scaria, Sonia M, Bar-Peled, Liron, Spooner, Eric, Isasa, Marta, Gygi, Steven P, Sabatini, David M

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Lyn kinase regulates egress of flaviviruses in autophagosome-derived organelles von Li, Ming Yuan, Naik, Trupti Shivaprasad, Siu, Lewis Yu Lam, Acuto, Oreste, Spooner, Eric, Wang, Peigang, Yang, Xiaohan, Lin, Yongping, Bruzzone, Roberto, Ashour, Joseph, Evans, Matthew J, Sanyal, Sumana

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Helicobacter pylori cytotoxin-associated gene A (CagA) subverts the apoptosis-stimulating protein of p53 (ASPP2) tumor suppressor pathway of the host von Buti, Ludovico, Spooner, Eric, Van der Veen, Annemarthe G, Rappuoli, Rino, Covacci, Antonello, Ploegh, Hidde L

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Haploid Genetic Screens in Human Cells Identify Host Factors Used by Pathogens von Carette, Jan E, Guimaraes, Carla P, Varadarajan, Malini, Park, Annie S, Wuethrich, Irene, Godarova, Alzbeta, Kotecki, Maciej, Cochran, Brent H, Spooner, Eric, Ploegh, Hidde L, Brummelkamp, Thijn R

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Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9 von Park, Boyoun, Brinkmann, Melanie M, Spooner, Eric, Lee, Clarissa C, Kim, You-Me, Ploegh, Hidde L

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interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling von Brinkmann, Melanie M, Spooner, Eric, Hoebe, Kasper, Beutler, Bruce, Ploegh, Hidde L, Kim, You-Me

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Dual Role of Ancient Ubiquitous Protein 1 (AUP1) in Lipid Droplet Accumulation and Endoplasmic Reticulum (ER) Protein Quality Control von Klemm, Elizabeth J., Spooner, Eric, Ploegh, Hidde L.

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Reversal of Histone Lysine Trimethylation by the JMJD2 Family of Histone Demethylases von Whetstine, Johnathan R., Nottke, Amanda, Lan, Fei, Huarte, Maite, Smolikov, Sarit, Chen, Zhongzhou, Spooner, Eric, Li, En, Zhang, Gongyi, Colaiacovo, Monica, Shi, Yang

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Impaired Autophagy in the Lipid-Storage Disorder Niemann-Pick Type C1 Disease von Sarkar, Sovan, Carroll, Bernadette, Buganim, Yosef, Maetzel, Dorothea, Ng, Alex H.M., Cassady, John P., Cohen, Malkiel A., Chakraborty, Souvik, Wang, Haoyi, Spooner, Eric, Ploegh, Hidde, Gsponer, Joerg, Korolchuk, Viktor I., Jaenisch, Rudolf

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Granulin Is a Soluble Cofactor for Toll-like Receptor 9 Signaling von Park, Boyoun, Buti, Ludovico, Lee, Sungwook, Matsuwaki, Takashi, Spooner, Eric, Brinkmann, Melanie M., Nishihara, Masugi, Ploegh, Hidde L.

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The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response von Niedelman, Wendy, Gold, Daniel A, Rosowski, Emily E, Sprokholt, Joris K, Lim, Daniel, Farid Arenas, Ailan, Melo, Mariane B, Spooner, Eric, Yaffe, Michael B, Saeij, Jeroen P J

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Sortase-catalyzed transformations that improve the properties of cytokines von Popp, Maximilian W, Dougan, Stephanie K, Chuang, Tzu-Ying, Spooner, Eric, Ploegh, Hidde L

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SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins von Mueller, Britta, Klemm, Elizabeth J, Spooner, Eric, Claessen, Jasper H, Ploegh, Hidde L

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Protein Ligation in Living Cells Using Sortase von Strijbis, Karin, Spooner, Eric, Ploegh, Hidde L.

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Sortase-mediated modification of αDEC205 affords optimization of antigen presentation and immunization against a set of viral epitopes von Swee, Lee Kim, Guimaraes, Carla P., Sehrawat, Sharvan, Spooner, Eric, Barrasa, M. Inmaculada, Ploegh, Hidde L.

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Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling von Jahan, Akhee S., Lestra, Maxime, Swee, Lee Kim, Fan, Ying, Lamers, Mart M., Tafesse, Fikadu G., Theile, Christopher S., Spooner, Eric, Bruzzone, Roberto, Ploegh, Hidde L., Sanyal, Sumana

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A Straight Path to Circular Proteins von Antos, John M., Popp, Maximilian Wei-Lin, Ernst, Robert, Chew, Guo-Liang, Spooner, Eric, Ploegh, Hidde L.

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Toxoplasma gondii Inhibits Gamma Interferon (IFN-γ)- and IFN-β-Induced Host Cell STAT1 Transcriptional Activity by Increasing the Association of STAT1 with DNA von Rosowski, Emily E, Nguyen, Quynh P, Camejo, Ana, Spooner, Eric, Saeij, Jeroen P J

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Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it von Virreira Winter, Sebastian, Niedelman, Wendy, Jensen, Kirk D, Rosowski, Emily E, Julien, Lindsay, Spooner, Eric, Caradonna, Kacey, Burleigh, Barbara A, Saeij, Jeroen P J, Ploegh, Hidde L, Frickel, Eva-Maria

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Role of the ubiquitin-like protein Urm1 as a noncanonical lysine-directed protein modifier von Van der Veen, Annemarthe G, Schorpp, Kenji, Schlieker, Christian, Buti, Ludovico, Damon, Jadyn R, Spooner, Eric, Ploegh, Hidde L, Jentsch, Stefan

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