Biology and regulation of IL-2: from molecular mechanisms to human therapy von Spolski, Rosanne, Li, Peng, Leonard, Warren J.

Volltext

Interleukin-21: basic biology and implications for cancer and autoimmunity von Spolski, Rosanne, Leonard, Warren J

Volltext

IL-21 and T follicular helper cells von Spolski, Rosanne, Leonard, Warren J.

Volltext

Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation von Leonard, Warren J., Spolski, Rosanne

Volltext

Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells von Lin, Jian-Xin, Du, Ning, Li, Peng, Kazemian, Majid, Gebregiorgis, Tesfay, Spolski, Rosanne, Leonard, Warren J.

Volltext

IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways von Zhou, Liang, Ivanov, Ivaylo I, Spolski, Rosanne, Min, Roy, Shenderov, Kevin, Egawa, Takeshi, Levy, David E, Leonard, Warren J, Littman, Dan R

Volltext

Thymic stromal lymphopoietin is produced by dendritic cells von Kashyap, Mohit, Rochman, Yrina, Spolski, Rosanne, Samsel, Leigh, Leonard, Warren J

Volltext

The γ c family of cytokines: fine-tuning signals from IL-2 and IL-21 in the regulation of the immune response [version 1; peer review: 3 approved] von Spolski, Rosanne, Gromer, Daniel, Leonard, Warren J

Volltext

Opposing actions of IL-2 and IL-21 on Th9 differentiation correlate with their differential regulation of BCL6 expression von Liao, Wei, Spolski, Rosanne, Li, Peng, Du, Ning, West, Erin E., Ren, Min, Mitra, Suman, Leonard, Warren J.

Volltext

IL-21 signaling is critical for the development of type I diabetes in the NOD mouse von Spolski, Rosanne, Kashyap, Mohit, Robinson, Constance, Yu, Zuxi, Leonard, Warren J

Volltext

The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer von Spolski, Rosanne, Leonard, Warren J

Volltext

Tyrosine phosphorylation of both STAT5A and STAT5B is necessary for maximal IL-2 signaling and T cell proliferation von Lin, Jian-Xin, Ge, Meili, Liu, Cheng-yu, Holewinski, Ronald, Andresson, Thorkell, Yu, Zu-Xi, Gebregiorgis, Tesfay, Spolski, Rosanne, Li, Peng, Leonard, Warren J.

Volltext

A new pipeline SPICE identifies novel JUN-IKZF1 composite elements von Li, Peng, Pulugulla, Sree, Das, Sonali, Oh, Jangsuk, Spolski, Rosanne, Lin, Jian-Xin, Leonard, Warren J

Volltext

Opposing roles of STAT1 and STAT3 in IL-21 function in CD4⁺ T cells von Wan, Chi-Keung, Andraski, Allison B., Spolski, Rosanne, Li, Peng, Kazemian, Majid, Oh, Jangsuk, Samsel, Leigh, Swanson, Phillip A., McGavern, Dorian B., Sampaio, Elizabeth P., Freeman, Alexandra F., Milner, Joshua D., Holland, Steven M., Leonard, Warren J.

Volltext

Adoptively transferred effector cells derived from naïve rather than central memory CD8⁺ T cells mediate superior antitumor immunity von Hinrichs, Christian S, Borman, Zachary A, Cassard, Lydie, Gattinoni, Luca, Spolski, Rosanne, Yu, Zhiya, Sanchez-Perez, Luis, Muranski, Pawel, Kern, Steven J, Logun, Carol, Palmer, Douglas C, Ji, Yun, Reger, Robert N, Leonard, Warren J, Danner, Robert L, Rosenberg, Steven A, Restifo, Nicholas P

Volltext

A role for TSLP in the development of inflammation in an asthma model von Al-Shami, Amin, Spolski, Rosanne, Kelly, John, Keane-Myers, Andrea, Leonard, Warren J

Volltext

The molecular basis of IL-21–mediated proliferation von Zeng, Rong, Spolski, Rosanne, Casas, Esther, Zhu, Wei, Levy, David E., Leonard, Warren J.

Volltext

Regulatory B cell (B10 Cell) expansion during Listeria infection governs innate and cellular immune responses in mice von Horikawa, Mayuka, Weimer, Eric T, DiLillo, David J, Venturi, Guglielmo M, Spolski, Rosanne, Leonard, Warren J, Heise, Mark T, Tedder, Thomas F

Volltext

critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice von Bubier, Jason A, Sproule, Thomas J, Foreman, Oded, Spolski, Rosanne, Shaffer, Daniel J, Morse, Herbert C. III, Leonard, Warren J, Roopenian, Derry C

Volltext

Thymic stromal lymphopoietin limits primary and recall CD8 + T-cell anti-viral responses von Ebina-Shibuya, Risa, West, Erin E, Spolski, Rosanne, Li, Peng, Oh, Jangsuk, Kazemian, Majid, Gromer, Daniel, Swanson, Phillip, Du, Ning, McGavern, Dorian B, Leonard, Warren J

Volltext