Next-generation Fc receptor–targeting biologics for autoimmune diseases von Zuercher, Adrian W., Spirig, Rolf, Baz Morelli, Adriana, Rowe, Tony, Käsermann, Fabian

Volltext

Recombinant IgG1 Fc hexamers block cytotoxicity and pathological changes in experimental in vitro and rat models of neuromyelitis optica von Tradtrantip, Lukmanee, Felix, Christian M., Spirig, Rolf, Morelli, Adriana Baz, Verkman, A.S.

Volltext

rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and FcγRs von Spirig, Rolf, Campbell, Ian K, Koernig, Sandra, Chen, Chao-Guang, Lewis, Bonnie J B, Butcher, Rebecca, Muir, Ineke, Taylor, Shirley, Chia, Jenny, Leong, David, Simmonds, Jason, Scotney, Pierre, Schmidt, Peter, Fabri, Louis, Hofmann, Andreas, Jordi, Monika, Spycher, Martin O, Cattepoel, Susann, Brasseit, Jennifer, Panousis, Con, Rowe, Tony, Branch, Donald R, Baz Morelli, Adriana, Käsermann, Fabian, Zuercher, Adrian W

Volltext

Neutrophil extracellular traps and citrullinated fibrinogen contribute to injury in a porcine model of limb ischemia and reperfusion von Zollet, Valentina, Arenas Hoyos, Isabel, Hirsiger, Stefanie, Brahim, Bilal Ben, Petrucci, Maria Francesca, Casoni, Daniela, Wang, Junhua, Spirig, Rolf, Nettelbeck, Kay, Garcia, Luisana, Fuest, Lena, Vögelin, Esther, Constantinescu, Mihai, Rieben, Robert

Volltext

Small-Molecule Immunosuppressive Drugs and Therapeutic Immunoglobulins Differentially Inhibit NK Cell Effector Functions in vitro von Pradier, Amandine, Papaserafeim, Maria, Li, Ning, Rietveld, Anke, Kaestel, Charlotte, Gruaz, Lyssia, Vonarburg, Cédric, Spirig, Rolf, Puga Yung, Gisella L, Seebach, Jörg D

Volltext

The Emerging Role of TLR and Innate Immunity in Cardiovascular Disease von Spirig, Rolf, Shaw, Sidney G., Tsui, Janice C. S.

Volltext

C1 esterase inhibitor reduces lower extremity ischemia/reperfusion injury and associated lung damage von Duehrkop, Claudia, Banz, Yara, Spirig, Rolf, Miescher, Sylvia, Nolte, Marc W, Spycher, Martin, Smith, Richard A G, Sacks, Steven H, Rieben, Robert

Volltext

Using the K/BxN mouse model of endogenous, chronic, rheumatoid arthritis for the evaluation of potential immunoglobulin-based therapeutic agents, including IVIg and Fc-μTP-L309C, a... von Lewis, Bonnie J B, Ville, Jade, Blacquiere, Megan, Cen, Selena, Spirig, Rolf, Zuercher, Adrian W, Käsermann, Fabian, Branch, Donald R

Volltext

Reconstituted high-density lipoprotein modulates activation of human leukocytes von Spirig, Rolf, Schaub, Alexander, Kropf, Alain, Miescher, Sylvia, Spycher, Martin O, Rieben, Robert

Volltext

Mechanism of increased efficacy of recombinant Fc‐μTP‐L309C compared to IVIg to ameliorate mouse immune thrombocytopenia von Lewis, Bonnie J.B., Binnington, Beth, Blacquiere, Megan, Spirig, Rolf, Käsermann, Fabian, Branch, Donald R.

Volltext

Low molecular weight dextran sulfate as complement inhibitor and cytoprotectant in solid organ and islet transplantation von Spirig, Rolf, Gajanayake, Thusitha, Korsgren, Olle, Nilsson, Bo, Rieben, Robert

Volltext

TLR2 and TLR4 agonists induce production of the vasoactive peptide endothelin-1 by human dendritic cells von Spirig, Rolf, Potapova, Inga, Shaw-Boden, Jane, Tsui, Janice, Rieben, Robert, Shaw, Sidney G.

Volltext

IVIG in autoimmune disease – Potential next generation biologics von Zuercher, Adrian W, Spirig, Rolf, Morelli, Adriana Baz, Käsermann, Fabian

Volltext

IgG hexamers initiate complement-dependent acute lung injury von Cleary, Simon J, Seo, Yurim, Tian, Jennifer J, Kwaan, Nicholas, Bulkley, David P, Bentlage, Arthur Eh, Vidarsson, Gestur, Boilard, Éric, Spirig, Rolf, Zimring, James C, Looney, Mark R

Volltext

Effects of C1 inhibitor on endothelial cell activation in a rat hind limb ischemia-reperfusion injury model von Zhang, Shengye, Shaw-Boden, Jane, Banz, Yara, Bongoni, Anjan K., Taddeo, Adriano, Spirig, Rolf, Nolte, Marc W., Cowan, Peter J., Rieben, Robert

Volltext

Effect of intravenous IgG therapy on natural killer cell function related to Fc gamma receptor gene expression von Papaserafeim, Maria, Jandus, Peter, Iancu Ferfoglia, Ruxandra, Nieke, Jan P., Vonarburg, Cédric, Spirig, Rolf, Puga Yung, Gisella L., Seebach, Jörg D.

Volltext

Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis von Almizraq, Ruqayyah J., Frias Boligan, Kayluz, Lewis, Bonnie J.B., Cen, Selena, Whetstone, Heather, Spirig, Rolf, Käsermann, Fabian, Campbell, Ian K., von Gunten, Stephan, Branch, Donald R.

Volltext

Effects of TLR Agonists on the Hypoxia-Regulated Transcription Factor HIF-1α and Dendritic Cell Maturation under Normoxic Conditions von Spirig, Rolf, Djafarzadeh, Siamak, Regueira, Tomas, Shaw, Sidney G., von Garnier, Christophe, Takala, Jukka, Jakob, Stephan M., Rieben, Robert, Lepper, Philipp M.

Volltext

Using the K/BxN mouse model of endogenous, chronic, rheumatoid arthritis for the evaluation of potential immunoglobulin-based therapeutic agents, including IVIg and Fc-[mu]TP-L309C... von Lewis, Bonnie J. B, Ville, Jade, Blacquiere, Megan, Cen, Selena, Spirig, Rolf, Zuercher, Adrian W, Käsermann, Fabian, Branch, Donald R

Volltext

Effects of TLR agonists on the hypoxia-regulated transcription factor HIF-1alpha and dendritic cell maturation under normoxic conditions von Spirig, Rolf, Djafarzadeh, Siamak, Regueira, Tomas, Shaw, Sidney G, von Garnier, Christophe, Takala, Jukka, Jakob, Stephan M, Rieben, Robert, Lepper, Philipp M

Volltext