Copy number alterations assessed at the single-cell level revealed mono- and polyclonal seeding patterns of distant metastasis in a small-cell lung cancer patient von Ferronika, P., van den Bos, H., Taudt, A., Spierings, D.C.J., Saber, A., Hiltermann, T.J.N., Kok, K., Porubsky, D., van der Wekken, A.J., Timens, W., Foijer, F., Colomé-Tatché, M., Groen, H.J.M., Lansdorp, P.M., van den Berg, A.

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Indomethacin-induced activation of the death receptor-mediated apoptosis pathway circumvents acquired doxorubicin resistance in SCLC cells von DE GROOT, D. J. A, TIMMER, T, SPIERINGS, D. C. J, LE, T. K. P, DE JONG, S, DE VRIES, E. G. E

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Characterization of antigen-presenting properties of tumour cells using virus-specific cytotoxic T lymphocytes von SPIERINGS, D. C. J, AGSTERIBBE, E, WILSCHUT, J, HUCKRIEDE, A

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Loss of drug-induced activation of the CD95 apoptotic pathway in a cisplatin-resistant testicular germ cell tumor cell line von Spierings, D C J, de Vries, E G E, Vellenga, E, de Jong, S

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Characterization of antigen-presenting properties of tumour cells using virus-specific cytotoxic T lymphocytes von Spierings, D C J, Agsteribbe, E, Wilschut, J, Huckriede, A

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β1‐integrins dominate cell traffic of leukemic cells in human bone‐marrow stroma von Van der Velde‐Zimmermann, Detlef, Smits, Veronique A. J., Verdaasdonk, Marina A. M., Rademakers, Louk H. P. M., Werner, Naomi, Spierings, Diana C. J., De Weger, Roel A., Van den Tweel, Jan G., Joling, Piet

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Safety and efficacy of LY2951742, a monoclonal antibody to calcitonin gene-related peptide, for the prevention of migraine: a phase 2, randomised, double-blind, placebo-controlled... von Dodick, David W, Prof, Goadsby, Peter J, Prof, Spierings, Egilius L H, Prof, Scherer, Joel C, MD, Sweeney, Steven P, BSc, Grayzel, David S, MD

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A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity von Nelson, Louisa, Tighe, Anthony, Golder, Anya, Littler, Samantha, Bakker, Bjorn, Moralli, Daniela, Murtuza Baker, Syed, Donaldson, Ian J., Spierings, Diana C. J., Wardenaar, René, Neale, Bethanie, Burghel, George J., Winter-Roach, Brett, Edmondson, Richard, Clamp, Andrew R., Jayson, Gordon C., Desai, Sudha, Green, Catherine M., Hayes, Andy, Foijer, Floris, Morgan, Robert D., Taylor, Stephen S.

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Copy number alterations assessed at the single-cell level revealed mono- and polyclonal seeding patterns of distant metastasis in a small-cell lung cancer patient von Ferronika, P, van den Bos, H, Taudt, A, Spierings, D C J, Saber, A, Hiltermann, T J N, Kok, K, Porubsky, D, van der Wekken, A J, Timens, W, Foijer, F, Colomé-Tatché, M, Groen, H J M, Lansdorp, P M, van den Berg, A

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Modulation of death receptor pathways in oncology von de Vries, E G E, Timmer, T, Mulder, N H, van Geelen, C M M, van der Graaf, W T A, Spierings, D C J, de Hooge, M N, Gietema, J A, de Jong, S

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Improved assembly and variant detection of a haploid human genome using single‐molecule, high‐fidelity long reads von Vollger, Mitchell R., Logsdon, Glennis A., Audano, Peter A., Sulovari, Arvis, Porubsky, David, Peluso, Paul, Wenger, Aaron M., Concepcion, Gregory T., Kronenberg, Zev N., Munson, Katherine M., Baker, Carl, Sanders, Ashley D., Spierings, Diana C.J., Lansdorp, Peter M., Surti, Urvashi, Hunkapiller, Michael W., Eichler, Evan E.

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Single-cell template strand sequencing by Strand-seq enables the characterization of individual homologs von Sanders, Ashley D, Falconer, Ester, Hills, Mark, Spierings, Diana C J, Lansdorp, Peter M

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DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors von Pillay, Nisha, Tighe, Anthony, Nelson, Louisa, Littler, Samantha, Coulson-Gilmer, Camilla, Bah, Nourdine, Golder, Anya, Bakker, Bjorn, Spierings, Diana C.J., James, Dominic I., Smith, Kate M., Jordan, Allan M., Morgan, Robert D., Ogilvie, Donald J., Foijer, Floris, Jackson, Dean A., Taylor, Stephen S.

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Randomized, double-blind, placebo-controlled, parallel-group, multi-center study of the safety and efficacy of ADAM zolmitriptan for the acute treatment of migraine von Spierings, Egilius LH, Brandes, Jan Lewis, Kudrow, David B, Weintraub, James, Schmidt, Peter C, Kellerman, Donald J, Tepper, Stewart J

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A phase III placebo- and oxycodone-controlled study of tanezumab in adults with osteoarthritis pain of the hip or knee von Spierings, Egilius L.H., Fidelholtz, James, Wolfram, Gernot, Smith, Michael D., Brown, Mark T., West, Christine R.

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Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models von Coulson-Gilmer, Camilla, Morgan, Robert D., Nelson, Louisa, Barnes, Bethany M., Tighe, Anthony, Wardenaar, Rene, Spierings, Diana C. J., Schlecht, Helene, Burghel, George J., Foijer, Floris, Desai, Sudha, McGrail, Joanne C., Taylor, Stephen S.

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Efficacy and safety of tanezumab monotherapy or combined with non-steroidal anti-inflammatory drugs in the treatment of knee or hip osteoarthritis pain von Schnitzer, Thomas J, Ekman, Evan F, Spierings, Egilius L H, Greenberg, H Scott, Smith, Michael D, Brown, Mark T, West, Christine R, Verburg, Kenneth M

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Safety and efficacy of ALD403, an antibody to calcitonin gene-related peptide, for the prevention of frequent episodic migraine: a randomised, double-blind, placebo-controlled, exp... von Dodick, David W, Prof, Goadsby, Peter J, Prof, Silberstein, Stephen D, Prof, Lipton, Richard B, Prof, Olesen, Jes, Prof, Ashina, Messoud, Prof, Wilks, Kerri, MD, Kudrow, David, MD, Kroll, Robin, MD, Kohrman, Bruce, MD, Bargar, Robert, MD, Hirman, Joe, PhD, Smith, Jeff, MD

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Direct chromosome-length haplotyping by single-cell sequencing von Porubský, David, Sanders, Ashley D, van Wietmarschen, Niek, Falconer, Ester, Hills, Mark, Spierings, Diana C J, Bevova, Marianna R, Guryev, Victor, Lansdorp, Peter M

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Circulating tumor DNA guided adjuvant chemotherapy in stage II colon cancer (MEDOCC-CrEATE): study protocol for a trial within a cohort study von Schraa, S. J., van Rooijen, K. L., van der Kruijssen, D. E. W., Alarcon, C. Rubio, Phallen, J., Sausen, M., Simmons, J., Coupe, V. M. H., van Grevenstein, W. M. U., Elias, S., Verkooijen, H. M., Lacle, M. M., Bosch, L. J. W., van den Broek, D., Meijer, G. A., Velculescu, V. E., Fijneman, R. J. A., Vink, G. R., Koopman, M.

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