New vaccines needed for pathogens infecting animals and humans: One Health von Gutiérrez, Andres H., Spero, Denice, Gay, Cyril, Zimic, Mirko, De Groot, Anne S.

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Discovery of potent and selective PKC-θ inhibitors von Cywin, Charles L., Dahmann, Georg, Prokopowicz, Anthony S., Young, Erick R.R., Magolda, Ronald L., Cardozo, Mario G., Cogan, Derek A., DiSalvo, Darren, Ginn, John D., Kashem, Mohammed A., Wolak, John P., Homon, Carol A., Farrell, Thomas M., Grbic, Heather, Hu, Hanbo, Kaplita, Paul V., Liu, Lisa H., Spero, Denice M., Jeanfavre, Deborah D., O’Shea, Kathy M., White, Della M., Woska, Joseph R., Brown, Maryanne L.

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Design and Synthesis of Dipeptide Nitriles as Reversible and Potent Cathepsin S Inhibitors von Ward, Yancey D, Thomson, David S, Frye, Leah L, Cywin, Charles L, Morwick, Tina, Emmanuel, Michel J, Zindell, Renée, McNeil, Daniel, Bekkali, Younes, Hrapchak, Matt, DeTuri, Molly, Crane, Kathy, White, Della, Pav, Susan, Wang, Yong, Hao, Ming-Hong, Grygon, Christine A, Labadia, Mark E, Freeman, Dorothy M, Davidson, Walter, Hopkins, Jerry L, Brown, Maryanne L, Spero, Denice M

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Total synthesis of halichondrin B and norhalichondrin B von Aicher, Thomas D, Buszek, Keith R, Fang, Francis G, Forsyth, Craig J, Jung, Sun Ho, Kishi, Yoshito, Matelich, Michael C, Scola, Paul M, Spero, Denice M, Yoon, Suk Kyoon

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Report from the field: Fifth vaccine renaissance in Providence RI von Spero, Denice, Petrovsky, Nikolai, De Groot, Annie S.

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Showcasing bioscience in Rhode Island von Spero, Denice

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Highly Diastereoselective Addition of Grignard Reagents to Aliphatic, Enolizable N-Alkylketimines and 2,2-Disubstituted 1,3-Oxazolidines. Asymmetric Synthesis of the Antidepressant... von Steinig, Arno G, Spero, Denice M

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Identification of a novel class of succinyl-nitrile-based Cathepsin S inhibitors von Bekkali, Younes, Thomson, David S., Betageri, Raj, Emmanuel, Michel J., Hao, Ming-Hong, Hickey, Eugene, Liu, Weimin, Patel, Usha, Ward, Yancey D., Young, Erick R.R., Nelson, Richard, Kukulka, Alison, Brown, Maryanne L., Crane, Kathy, White, Della, Freeman, Dorothy M., Labadia, Mark E., Wildeson, Jessi, Spero, Denice M.

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A Novel Method for the Asymmetric Synthesis of α,α-Disubstituted Alkylamines via Grignard Additions to Ketimines von Spero, Denice M, Kapadia, Suresh R

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An orally active reversible inhibitor of cathepsin S inhibits human trans vivo delayed-type hypersensitivity von Desai, Sudha N., White, Della M., O'Shea, Kathryn M., Brown, Maryanne L., Cywin, Charles L., Spero, Denice M., Panzenbeck, Maret J.

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Enantioselective Synthesis of α,α-Disubstituted Amino Acid Derivatives via Enzymatic Resolution:  Preparation of a Thiazolyl-Substituted α-Methyl α-Benzyl Amine von Spero, Denice M, Kapadia, Suresh R

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The design of potent hydrazones and disulfides as cathepsin S inhibitors von Cywin, Charles L, Firestone, Raymond A, McNeil, Daniel W, Grygon, Christine A, Crane, Kathryn M, White, Della M, Kinkade, Peter R, Hopkins, Jerry L, Davidson, Walter, Labadia, Mark E, Wildeson, Jessi, Morelock, Maurice M, Peterson, Jeffrey D, Raymond, Ernest L, Brown, Maryanne L, Spero, Denice M

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Enantioselective synthesis of the ( syn,anti)-1-amino-2,3-diol subunit of renin inhibitors by reaction of β-Lactams with a Grignard reagent von Spero, Denice M, Kapadia, Suresh, Farina, Vittorio

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Design and Synthesis of Dipeptide Nitriles as Reversible and Potent Cathepsin S Inhibitors von Ward, Yancey D, Thomson, David S, Frye, Leah L, Cywin, Charles L, Morwick, Tina, Emmanuel, Michel J, Zindell, Renée, McNeil, Daniel, Bekkali, Younes, Girardot, Marc, Hrapchak, Matt, DeTuri, Molly, Crane, Kathy, White, Della, Pav, Susan, Wang, Yong, Hao, Ming-Hong, Grygon, Christine A, Labadia, Mark E, Freeman, Dorothy M, Davidson, Walter, Hopkins, Jerry L, Brown, Maryanne L, Spero, Denice M

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Regiospecific control of Rh(II) carbenoids in the C-H insertion reaction von Spero, Denice M., Adams, Julian

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Report from the field: Overview of the Sixth Annual Vaccine Renaissance Conference von Spero, Denice, Levitz, Lauren

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Rhodium (II) catalyzed reactions of diazo-carbonyl compounds von Adams, Julian, Spero, Denice M.

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INTER-ALPHA INHIBITOR PROTEINS von Spero, Denice, Lim, Yow-Pin

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Benzoxazolamines and Benzothiazolamines: Potent, Enantioselective Inhibitors of Leukotriene Biosynthesis with a Novel Mechanism of Action von Lazer, Edward S, Miao, Clara K, Wong, Hin-Chor, Sorcek, Ronald, Spero, Denice M, Gilman, Alex, Pal, Kollol, Behnke, Mark, Graham, Anne G

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Immunogenic Consensus Sequence T helper Epitopes for a Pan- Burkholderia Biodefense Vaccine von De Groot, Anne S, Ardito, Matthew, Moise, Leonard, Gustafson, Eric A, Spero, Denice, Tejada, Gloria, Martin, William

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