Strategies for Targeting the NLRP3 Inflammasome in the Clinical and Preclinical Space von Schwaid, Adam G, Spencer, Kerrie B

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Targeting RNA with small molecules: lessons learned from Xist RNA von Nickbarg, Elliott B, Spencer, Kerrie B, Mortison, Jonathan D, Lee, Jeannie T

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Targeting Xist with compounds that disrupt RNA structure and X inactivation von Aguilar, Rodrigo, Spencer, Kerrie B., Kesner, Barry, Rizvi, Noreen F., Badmalia, Maulik D., Mrozowich, Tyler, Mortison, Jonathan D., Rivera, Carlos, Smith, Graham F., Burchard, Julja, Dandliker, Peter J., Patel, Trushar R., Nickbarg, Elliott B., Lee, Jeannie T.

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Structural insights on ligand recognition at the human leukotriene B4 receptor 1 von Michaelian, Nairie, Sadybekov, Anastasiia, Besserer-Offroy, Élie, Han, Gye Won, Krishnamurthy, Harini, Zamlynny, Beata A., Fradera, Xavier, Siliphaivanh, Phieng, Presland, Jeremy, Spencer, Kerrie B., Soisson, Stephen M., Popov, Petr, Sarret, Philippe, Katritch, Vsevolod, Cherezov, Vadim

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Discovery of a 5H-Benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) Inhibitor of c-Met Kinase for the Treatment of Cancer von Katz, Jason D, Jewell, James P, Guerin, David J, Lim, Jongwon, Dinsmore, Christopher J, Deshmukh, Sujal V, Pan, Bo-Sheng, Marshall, C. Gary, Lu, Wei, Altman, Michael D, Dahlberg, William K, Davis, Lenora, Falcone, Danielle, Gabarda, Ana E, Hang, Gaozhen, Hatch, Harold, Holmes, Rachael, Kunii, Kaiko, Lumb, Kevin J, Lutterbach, Bart, Mathvink, Robert, Nazef, Naim, Patel, Sangita B, Qu, Xianlu, Reilly, John F, Rickert, Keith W, Rosenstein, Craig, Soisson, Stephen M, Spencer, Kerrie B, Szewczak, Alexander A, Walker, Deborah, Wang, Wenxian, Young, Jonathan, Zeng, Qinwen

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Discovery of 1-Amino-5H-pyrido[4,3-b]indol-4-carboxamide Inhibitors of Janus Kinase 2 (JAK2) for the Treatment of Myeloproliferative Disorders von Lim, Jongwon, Taoka, Brandon, Otte, Ryan D, Spencer, Kerrie, Dinsmore, Christopher J, Altman, Michael D, Chan, Grace, Rosenstein, Craig, Sharma, Sujata, Su, Hua-Poo, Szewczak, Alexander A, Xu, Lin, Yin, Hong, Zugay-Murphy, Joan, Marshall, C. Gary, Young, Jonathan R

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Discovery of 1-Amino-5 H -pyrido[4,3- b ]indol-4-carboxamide Inhibitors of Janus Kinase 2 (JAK2) for the Treatment of Myeloproliferative Disorders von Lim, Jongwon, Taoka, Brandon, Otte, Ryan D., Spencer, Kerrie, Dinsmore, Christopher J., Altman, Michael D., Chan, Grace, Rosenstein, Craig, Sharma, Sujata, Su, Hua-Poo, Szewczak, Alexander A., Xu, Lin, Yin, Hong, Zugay-Murphy, Joan, Marshall, C. Gary, Young, Jonathan R.

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Discovery of a 5 H -Benzo[4,5]cyclohepta[1,2- b ]pyridin-5-one (MK-2461) Inhibitor of c-Met Kinase for the Treatment of Cancer von Katz, Jason D., Jewell, James P., Guerin, David J., Lim, Jongwon, Dinsmore, Christopher J., Deshmukh, Sujal V., Pan, Bo-Sheng, Marshall, C. Gary, Lu, Wei, Altman, Michael D., Dahlberg, William K., Davis, Lenora, Falcone, Danielle, Gabarda, Ana E., Hang, Gaozhen, Hatch, Harold, Holmes, Rachael, Kunii, Kaiko, Lumb, Kevin J., Lutterbach, Bart, Mathvink, Robert, Nazef, Naim, Patel, Sangita B., Qu, Xianlu, Reilly, John F., Rickert, Keith W., Rosenstein, Craig, Soisson, Stephen M., Spencer, Kerrie B., Szewczak, Alexander A., Walker, Deborah, Wang, Wenxian, Young, Jonathan, Zeng, Qinwen

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Overcoming Mutagenicity and Ion Channel Activity: Optimization of Selective Spleen Tyrosine Kinase Inhibitors von Ellis, J. Michael, Altman, Michael D, Bass, Alan, Butcher, John W, Byford, Alan J, Donofrio, Anthony, Galloway, Sheila, Haidle, Andrew M, Jewell, James, Kelly, Nancy, Leccese, Erica K, Lee, Sandra, Maddess, Matthew, Miller, J. Richard, Moy, Lily Y, Osimboni, Ekundayo, Otte, Ryan D, Reddy, M. Vijay, Spencer, Kerrie, Sun, Binyuan, Vincent, Stella H, Ward, Gwendolyn J, Woo, Grace H. C, Yang, Chiming, Houshyar, Hani, Northrup, Alan B

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Label-Free, LC-MS-Based Assays to Quantitate Small-Molecule Antagonist Binding to the Mammalian BLT1 Receptor von Chen, Xun, Stout, Steven, Mueller, Uwe, Boykow, George, Visconti, Richard, Siliphaivanh, Phieng, Spencer, Kerrie, Presland, Jeremy, Kavana, Michael, Basso, Andrea D., McLaren, David G., Myers, Robert W.

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ARYL SULFONAMIDES AS BLT1 ANTAGONISTS von SPENCER, Kerrie, TUMMANAPALLI, Satyanarayana, HAN, Yongxin, SILIPHAIVANH, Phieng

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ARYL SULFONAMIDES AS BLT1 ANTAGONISTS von Tummanapalli, Satyanarayana, Han, Yongxin, Spencer, Kerrie, Lim, Jongwon, Siliphaivanh, Phieng

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ARYL SULFONAMIDES AS BLT1 ANTAGONISTS von SPENCER, Kerrie, LIM, Jongwon, TUMMANAPALLI, Satyanarayana, HAN, Yongxin, SILIPHAIVANH, Phieng

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ARYL ACYLSULFONAMIDES AS BLT1 ANTAGONISTS von SPENCER, Kerrie, TUMMANAPALLI, Satyanarayana, HAN, Yongxin, SILIPHAIVANH, Phieng

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ARYL ACYLSULFONAMIDES AS BLT1 ANTAGONISTS von SPENCER, Kerrie, LIM, Jongwon, TUMMANAPALLI, Satyanarayana, HAN, Yongxin, SILIPHAIVANH, Phieng

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ARYL SULFONAMIDES AS BLT1 ANTAGONISTS von Tummanapalli, Satyanarayana, Han, Yongxin, Spencer, Kerrie, Lim, Jongwon, Siliphaivanh, Phieng

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Aryl sulfonamides as BLT1 antagonists von Tummanapalli, Satyanarayana, Han, Yongxin, Spencer, Kerrie, Siliphaivanh, Phieng

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Aryl acylsulfonamides as BLT1 antagonists von Tummanapalli, Satyanarayana, Han, Yongxin, Spencer, Kerrie, Siliphaivanh, Phieng

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ARYL SULFONAMIDES AS BLT1 ANTAGONISTS von SPENCER, Kerrie, TUMMANAPALLI, Satyanarayana, HAN, Yongxin, SILIPHAIVANH, Phieng

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ARYL ACYLSULFONAMIDES AS BLT1 ANTAGONISTS von SPENCER, Kerrie, LIM, Jongwon, TUMMANAPALLI, Satyanarayana, HAN, Yongxin, SILIPHAIVANH, Phieng

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