Ultra-thermostable RNA nanoparticles for solubilizing and high-yield loading of paclitaxel for breast cancer therapy von Guo, Sijin, Vieweger, Mario, Zhang, Kaiming, Yin, Hongran, Wang, Hongzhi, Li, Xin, Li, Shanshan, Hu, Shuiying, Sparreboom, Alex, Evers, B. Mark, Dong, Yizhou, Chiu, Wah, Guo, Peixuan

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Endogenous Biomarkers for SLC Transporter-Mediated Drug-Drug Interaction Evaluation von Li, Yang, Talebi, Zahra, Chen, Xihui, Sparreboom, Alex, Hu, Shuiying

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Quantitative and Mechanistic Understanding of AZD1775 Penetration across Human Blood-Brain Barrier in Glioblastoma Patients Using an IVIVE-PBPK Modeling Approach von Li, Jing, Wu, Jianmei, Bao, Xun, Honea, Norissa, Xie, Youming, Kim, Seongho, Sparreboom, Alex, Sanai, Nader

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Impact of Membrane Drug Transporters on Resistance to Small-Molecule Tyrosine Kinase Inhibitors von Neul, Claudia, Schaeffeler, Elke, Sparreboom, Alex, Laufer, Stefan, Schwab, Matthias, Nies, Anne T

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A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury von Kim, Ji Young, Bai, Yuntao, Jayne, Laura A., Hector, Ralph D., Persaud, Avinash K., Ong, Su Sien, Rojesh, Shreshtha, Raj, Radhika, Feng, Mei Ji He Ho, Chung, Sangwoon, Cianciolo, Rachel E., Christman, John W., Campbell, Moray J., Gardner, David S., Baker, Sharyn D., Sparreboom, Alex, Govindarajan, Rajgopal, Singh, Harpreet, Chen, Taosheng, Poi, Ming, Susztak, Katalin, Cobb, Stuart R., Pabla, Navjot Singh

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Role of Oatp2b1 in Drug Absorption and Drug-Drug Interactions von Chen, Mingqing, Hu, Shuiying, Li, Yang, Gibson, Alice A., Fu, Qiang, Baker, Sharyn D., Sparreboom, Alex

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Appropriate Chemotherapy Dosing for Obese Adult Patients With Cancer: American Society of Clinical Oncology Clinical Practice Guideline von GRIGGS, Jennifer J, MANGU, Pamela B, SHAYNE, Michelle, SPARREBOOM, Alex, SUCHESTON, Lara E, LYMAN, Gary H, ANDERSON, Holly, BALABAN, Edward P, DIGNAM, James J, HRYNIUK, William M, MORRISON, Vicki A, MAY PINI, T, RUNOWICZ, Carolyn D, ROSNER, Gary L

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Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2 von Sprowl, Jason A., Ciarimboli, Giuliano, Lancaster, Cynthia S., Giovinazzo, Hugh, Gibson, Alice A., Du, Guoqing, Janke, Laura J., Cavaletti, Guido, Shields, Anthony F., Sparreboom, Alex

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Polymorphic Transporters and Platinum Pharmacodynamics von Sprowl, Jason A., Ness, Rachel A., Sparreboom, Alex

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Germline Genetic Variation in an Organic Anion Transporter Polypeptide Associated With Methotrexate Pharmacokinetics and Clinical Effects von Treviño, Lisa R, Shimasaki, Noriko, Yang, Wenjian, Panetta, John C, Cheng, Cheng, Pei, Deqing, Chan, Diana, Sparreboom, Alex, Giacomini, Kathleen M, Pui, Ching-Hon, Evans, William E, Relling, Mary V

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Contribution of OATP1B1 and OATP1B3 to the disposition of sorafenib and sorafenib-glucuronide von Zimmerman, Eric I, Hu, Shuiying, Roberts, Justin L, Gibson, Alice A, Orwick, Shelley J, Li, Lie, Sparreboom, Alex, Baker, Sharyn D

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Adult stem cell deficits drive Slc29a3 disorders in mice von Nair, Sreenath, Strohecker, Anne M., Persaud, Avinash K., Bissa, Bhawana, Muruganandan, Shanmugam, McElroy, Craig, Pathak, Rakesh, Williams, Michelle, Raj, Radhika, Kaddoumi, Amal, Sparreboom, Alex, Beedle, Aaron M., Govindarajan, Rajgopal

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Neuronal uptake transporters contribute to oxaliplatin neurotoxicity in mice von Huang, Kevin M, Leblanc, Alix F, Uddin, Muhammad Erfan, Kim, Ji Young, Chen, Mingqing, Eisenmann, Eric D, Gibson, Alice A, Li, Yang, Hong, Kristen W, DiGiacomo, Duncan, Xia, Sherry H, Alberti, Paola, Chiorazzi, Alessia, Housley, Stephen N, Cope, Timothy C, Sprowl, Jason A, Wang, Jing, Loprinzi, Charles L, Noonan, Anne, Lustberg, Maryam B, Cavaletti, Guido, Pabla, Navjot, Hu, Shuiying, Sparreboom, Alex

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Mitigation of acute kidney injury by cell-cycle inhibitors that suppress both CDK4/6 and OCT2 functions von Pabla, Navjotsingh, Gibson, Alice A., Buege, Mike, Ong, Su Sien, Li, Lie, Hu, Shuiying, Du, Guoqing, Sprowl, Jason A., Vasilyeva, Aksana, Janke, Laura J., Schlatter, Eberhard, Chen, Taosheng, Ciarimboli, Giuliano, Sparreboom, Alex

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Targeting OCT3 attenuates doxorubicin-induced cardiac injury von Huang, Kevin M., Thomas, Megan Zavorka, Magdy, Tarek, Eisenmann, Eric D., Uddin, Muhammad Erfan, DiGiacomo, Duncan F., Pan, Alexander, Keiser, Markus, Otter, Marcus, Xia, Sherry H., Li, Yang, Jin, Yan, Fu, Qiang, Gibson, Alice A., Bonilla, Ingrid M., Carnes, Cynthia A., Corps, Kara N., Coppola, Vincenzo, Smith, Sakima A., Addison, Daniel, Nies, Anne T., Bundschuh, Ralf, Chen, Taosheng, Lustberg, Maryam B., Wang, Joanne, Oswald, Stefan, Campbell, Moray J., Yan, Pearlly S., Baker, Sharyn D., Hu, Shuiying, Burridge, Paul W., Sparreboom, Alex

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OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues von Drenberg, Christina D, Gibson, Alice A, Pounds, Stanley B, Shi, Lei, Rhinehart, Dena P, Li, Lie, Hu, Shuiying, Du, Guoqing, Nies, Anne T, Schwab, Matthias, Pabla, Navjotsingh, Blum, William, Gruber, Tanja A, Baker, Sharyn D, Sparreboom, Alex

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A phosphotyrosine switch regulates organic cation transporters von Sprowl, Jason A., Ong, Su Sien, Gibson, Alice A., Hu, Shuiying, Du, Guoqing, Lin, Wenwei, Li, Lie, Bharill, Shashank, Ness, Rachel A., Stecula, Adrian, Offer, Steven M., Diasio, Robert B., Nies, Anne T., Schwab, Matthias, Cavaletti, Guido, Schlatter, Eberhard, Ciarimboli, Giuliano, Schellens, Jan H. M., Isacoff, Ehud Y., Sali, Andrej, Chen, Taosheng, Baker, Sharyn D., Sparreboom, Alex, Pabla, Navjotsingh

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Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition von Ramsey, Laura B, Bruun, Gitte H, Yang, Wenjian, Treviño, Lisa R, Vattathil, Selina, Scheet, Paul, Cheng, Cheng, Rosner, Gary L, Giacomini, Kathleen M, Fan, Yiping, Sparreboom, Alex, Mikkelsen, Torben S, Corydon, Thomas J, Pui, Ching-Hon, Evans, William E, Relling, Mary V

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Role for Drug Transporters in Chemotherapy‐Induced Peripheral Neuropathy von Stage, Tore B., Hu, Shuiying, Sparreboom, Alex, Kroetz, Deanna L.

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Interaction of Cisplatin with the Human Organic Cation Transporter 2 von FILIPSKI, Kelly K, LOOS, Walter J, VERWEIJ, Jaap, SPARREBOOM, Alex

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