Decarboxylative Anti-Michael Addition to Olefins Mediated by Photoredox Catalysis von Lovett, Gabrielle H, Sparling, Brian A

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Enantioselective Total Synthesis of Hyperforin von Sparling, Brian A, Moebius, David C, Shair, Matthew D

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Total Synthesis of (−)-Nemorosone and (+)-Secohyperforin von Sparling, Brian A, Tucker, James K, Moebius, David C, Shair, Matthew D

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Virtual screening to identify potent sepiapterin reductase inhibitors von Gao, Hua, Schneider, Stephen, Andrews, Paul, Wang, Kevin, Huang, Xin, Sparling, Brian A.

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Progress in the discovery of small molecule modulators of the Cys-loop superfamily receptors von Sparling, Brian A., DiMauro, Erin F.

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Sustainable Practices in Medicinal Chemistry Part 2: Green by Design von Aliagas, Ignacio, Berger, Raphaëlle, Goldberg, Kristin, Nishimura, Rachel T, Reilly, John, Richardson, Paul, Richter, Daniel, Sherer, Edward C, Sparling, Brian A, Bryan, Marian C

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Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in Viv... von Graceffa, Russell F, Boezio, Alessandro A, Able, Jessica, Altmann, Steven, Berry, Loren M, Boezio, Christiane, Butler, John R, Chu-Moyer, Margaret, Cooke, Melanie, DiMauro, Erin F, Dineen, Thomas A, Feric Bojic, Elma, Foti, Robert S, Fremeau, Robert T, Guzman-Perez, Angel, Gao, Hua, Gunaydin, Hakan, Huang, Hongbing, Huang, Liyue, Ilch, Christopher, Jarosh, Michael, Kornecook, Thomas, Kreiman, Charles R, La, Daniel S, Ligutti, Joseph, Milgram, Benjamin C, Lin, Min-Hwa Jasmine, Marx, Isaac E, Nguyen, Hanh N, Peterson, Emily A, Rescourio, Gwen, Roberts, John, Schenkel, Laurie, Shimanovich, Roman, Sparling, Brian A, Stellwagen, John, Taborn, Kristin, Vaida, Karina R, Wang, Jean, Yeoman, John, Yu, Violeta, Zhu, Dawn, Moyer, Bryan D, Weiss, Matthew M

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Pharmacological Assessment of Sepiapterin Reductase Inhibition on Tactile Response in the Rat von Meyer, James T., Sparling, Brian A., McCarty, William J., Zhang, Maosheng, Soto, Marcus, Schneider, Stephen, Chen, Hao, Roberts, Jonathan, Tan, Helming, Kornecook, Thomas, Andrews, Paul S., Knutson, Charles G.

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Sustainable Practices in Medicinal Chemistry Part 2: Green by Design: Miniperspective von Aliagas, Ignacio, Berger, Raphaëlle, Goldberg, Kristin, Nishimura, Rachel T, Reilly, John, Richardson, Paul, Richter, Daniel, Sherer, Edward C, Sparling, Brian A, Bryan, Marian C

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High-Throughput Implementation of the NanoBRET Target Engagement Intracellular Kinase Assay to Reveal Differential Compound Engagement by SIK2/3 Isoforms von Jin, Hyun Yong, Tudor, Yanyan, Choi, Kaylee, Shao, Zhifei, Sparling, Brian A., McGivern, Joseph G., Symons, Antony

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Sulfonamides as Selective Na V 1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in V... von Graceffa, Russell F, Boezio, Alessandro A, Able, Jessica, Altmann, Steven, Berry, Loren M, Boezio, Christiane, Butler, John R, Chu-Moyer, Margaret, Cooke, Melanie, DiMauro, Erin F, Dineen, Thomas A, Feric Bojic, Elma, Foti, Robert S, Fremeau, Jr, Robert T, Guzman-Perez, Angel, Gao, Hua, Gunaydin, Hakan, Huang, Hongbing, Huang, Liyue, Ilch, Christopher, Jarosh, Michael, Kornecook, Thomas, Kreiman, Charles R, La, Daniel S, Ligutti, Joseph, Milgram, Benjamin C, Lin, Min-Hwa Jasmine, Marx, Isaac E, Nguyen, Hanh N, Peterson, Emily A, Rescourio, Gwen, Roberts, John, Schenkel, Laurie, Shimanovich, Roman, Sparling, Brian A, Stellwagen, John, Taborn, Kristin, Vaida, Karina R, Wang, Jean, Yeoman, John, Yu, Violeta, Zhu, Dawn, Moyer, Bryan D, Weiss, Matthew M

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Strategic use of nickel(0)-catalyzed enyne–epoxide reductive coupling toward the synthesis of (−)-cyatha-3,12-diene von Sparling, Brian A., Simpson, Graham L., Jamison, Timothy F.

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Discovery and hit-to-lead evaluation of piperazine amides as selective, state-dependent NaV1.7 inhibitors von Sparling, Brian A, Yi, S, Able, J, Bregman, H, DiMauro, Erin F, Foti, R S, Gao, H, Guzman-Perez, A, Huang, H, Jarosh, M, Kornecook, T, Ligutti, J, Milgram, B C, Moyer, B D, Youngblood, B, Yu, V L, Weiss, M M

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Discovery and hit-to-lead evaluation of piperazine amides as selective, state-dependent Na V 1.7 inhibitors von Sparling, Brian A, Yi, S, Able, J, Bregman, H, DiMauro, Erin F, Foti, R S, Gao, H, Guzman-Perez, A, Huang, H, Jarosh, M, Kornecook, T, Ligutti, J, Milgram, B C, Moyer, B D, Youngblood, B, Yu, V L, Weiss, M M

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Strategic use of nickel(0)-catalyzed enyne-epoxide reductive coupling towards the synthesis of (-)-cyatha-3,12-diene von Sparling, Brian A, Simpson, Graham L, Jamison, Timothy F

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SmI2-Promoted Reformatsky-Type Coupling Reactions in Exceptionally Hindered Contexts von Sparling, Brian A, Moslin, Ryan M, Jamison, Timothy F

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Abstract A163: Exoribonuclease XRN1 is a therapeutic vulnerability in tumors with intrinsically elevated type I interferon signaling von Lynes, Maureen M, Shen, Sophie A, Nayak, Sunaina P, Sparling, Brian A, Ribich, Scott, Blakemore, Stephen J, Silver, Serena J

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Abstract B073: Characterization of selective, allosteric inhibitors of human XRN1 von Lockbaum, Gordon J, Sickmier, E. Allen, Sparling, Brian A, Knockenhauer, Kevin, Holt, Nicholas, Liu, Julie, Lynes, Maureen M, Grigoriu, Simina, Duncan, Kenneth W, Copeland, Robert A, Boriack-Sjodin, P. Ann

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ChemInform Abstract: Decarboxylative anti‐Michael Addition to Olefins Mediated by Photoredox Catalysis von Lovett, Gabrielle H., Sparling, Brian A.

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Abstract 1136: Targeting DHX9 inhibition as a novel therapeutic modality in microsatellite instable colorectal cancer von Castro, Jennifer, Daniels, Matthew H., Lu, Chuang, Brennan, David, Gotur, Deepali, Lee, Young-Tae, Knockenhauer, Kevin, Case, April, Wu, Jie, Buker, Shane M., Liu, Julie, Sparling, Brian A., Sickmier, E. Allen, Blakemore, Stephen J., Boriack-Sjodin, P. Ann, Duncan, Kenneth W., Ribich, Scott, Copeland, Robert A.

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