BRCA2-DSS1 interaction is dispensable for RAD51 recruitment at replication-induced and meiotic DNA double strand breaks von Mishra, Arun Prakash, Hartford, Suzanne A., Sahu, Sounak, Klarmann, Kimberly, Chittela, Rajani Kant, Biswas, Kajal, Jeon, Albert B., Martin, Betty K., Burkett, Sandra, Southon, Eileen, Reid, Susan, Albaugh, Mary E., Karim, Baktiar, Tessarollo, Lino, Keller, Jonathan R., Sharan, Shyam K.

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Saturation genome editing of 11 codons and exon 13 of BRCA2 coupled with chemotherapeutic drug response accurately determines pathogenicity of variants von Sahu, Sounak, Sullivan, Teresa L, Mitrophanov, Alexander Y, Galloux, Mélissa, Nousome, Darryl, Southon, Eileen, Caylor, Dylan, Mishra, Arun Prakash, Evans, Christine N, Clapp, Michelle E, Burkett, Sandra, Malys, Tyler, Chari, Raj, Biswas, Kajal, Sharan, Shyam K

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Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2 von Hartford, Suzanne A, Chittela, Rajanikant, Ding, Xia, Vyas, Aradhana, Martin, Betty, Burkett, Sandra, Haines, Diana C, Southon, Eileen, Tessarollo, Lino, Sharan, Shyam K

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Essential Role of the Zinc Finger Transcription Factor Casz1 for Mammalian Cardiac Morphogenesis and Development von Liu, Zhihui, Li, Wenling, Ma, Xuefei, Ding, Nancy, Spallotta, Francesco, Southon, Eileen, Tessarollo, Lino, Gaetano, Carlo, Mukouyama, Yoh-suke, Thiele, Carol J.

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Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn von Hasumi, Hisashi, Baba, Masaya, Hasumi, Yukiko, Lang, Martin, Huang, Ying, Oh, HyoungBin F., Matsuo, Masayuki, Merino, Maria J., Yao, Masahiro, Ito, Yusuke, Furuya, Mitsuko, Iribe, Yasuhiro, Kodama, Tatsuhiko, Southon, Eileen, Tessarollo, Lino, Nagashima, Kunio, Haines, Diana C., Linehan, W. Marston, Schmidt, Laura S.

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A novel mouse model of PMS2 founder mutation that causes mismatch repair defect due to aberrant splicing von Biswas, Kajal, Couillard, Martin, Cavallone, Luca, Burkett, Sandra, Stauffer, Stacey, Martin, Betty K., Southon, Eileen, Reid, Susan, Plona, Teri M., Baugher, Ryan N., Mellott, Stephanie D., Pike, Kristen M., Albaugh, Mary E., Maedler-Kron, Chelsea, Hamel, Nancy, Tessarollo, Lino, Marcus, Victoria, Foulkes, William D., Sharan, Shyam K.

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A computational model for classification of BRCA2 variants using mouse embryonic stem cell-based functional assays von Biswas, Kajal, Lipton, Gary B., Stauffer, Stacey, Sullivan, Teresa, Cleveland, Linda, Southon, Eileen, Reid, Susan, Magidson, Valentin, Iversen, Edwin S., Sharan, Shyam K.

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Functional evaluation of five BRCA2 unclassified variants identified in a Sri Lankan cohort with inherited cancer syndromes using a mouse embryonic stem cell-based assay von Sirisena, Nirmala, Biswas, Kajal, Sullivan, Teresa, Stauffer, Stacey, Cleveland, Linda, Southon, Eileen, Dissanayake, Vajira H. W., Sharan, Shyam K.

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Characterization of BRCA2 R3052Q variant in mice supports its functional impact as a low-risk variant von Mishra, Arun Prakash, Hartford, Suzanne, Chittela, Rajani Kant, Sahu, Sounak, Kharat, Suhas S., Alvaro-Aranda, Lucia, Contreras-Perez, Aida, Sullivan, Teresa, Martin, Betty K., Albaugh, Mary, Southon, Eileen, Burkett, Sandra, Karim, Baktiar, Carreira, Aura, Tessarollo, Lino, Sharan, Shyam K.

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An inducible and reversible mouse genetic rescue system von Zeng, Hongkui, Horie, Kyoji, Madisen, Linda, Pavlova, Maria N, Gragerova, Galina, Rohde, Alex D, Schimpf, Brian A, Liang, Yuqiong, Ojala, Ethan, Kramer, Farah, Roth, Patricia, Slobodskaya, Olga, Dolka, Io, Southon, Eileen A, Tessarollo, Lino, Bornfeldt, Karin E, Gragerov, Alexander, Pavlakis, George N, Gaitanaris, George A

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Fgf3-Fgf4-cis: A new mouse line for studying Fgf functions during mouse development von Anderson, Matthew J., Southon, Eileen, Tessarollo, Lino, Lewandoski, Mark

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The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development von Baba, Masaya, Keller, Jonathan R., Sun, Hong-Wei, Resch, Wolfgang, Kuchen, Stefan, Suh, Hyung Chan, Hasumi, Hisashi, Hasumi, Yukiko, Kieffer-Kwon, Kyong-Rim, Gonzalez, Carme Gallego, Hughes, Robert M., Klein, Mara E., Oh, Hyoungbin F., Bible, Paul, Southon, Eileen, Tessarollo, Lino, Schmidt, Laura S., Linehan, W. Marston, Casellas, Rafael

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Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells von Landry, Joseph, Sharov, Alexei A, Piao, Yulan, Sharova, Lioudmila V, Xiao, Hua, Southon, Eileen, Matta, Jennifer, Tessarollo, Lino, Zhang, Ying E, Ko, Minoru S H, Kuehn, Michael R, Yamaguchi, Terry P, Wu, Carl

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Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap) von Mahdi, Yassin, Xu, Xue-Ming, Carlson, Bradley A, Fradejas, Noelia, Günter, Paul, Braun, Doreen, Southon, Eileen, Tessarollo, Lino, Hatfield, Dolph L, Schweizer, Ulrich

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Sequencing-based functional assays for classification of BRCA2 variants in mouse ESCs von Biswas, Kajal, Mitrophanov, Alexander Y, Sahu, Sounak, Sullivan, Teresa, Southon, Eileen, Nousome, Darryl, Reid, Susan, Narula, Sakshi, Smolen, Julia, Sengupta, Trisha, Riedel-Topper, Maximilian, Kapoor, Medha, Babbar, Anav, Stauffer, Stacey, Cleveland, Linda, Tandon, Mayank, Malys, Tyler, Sharan, Shyam K

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Ablation of TrkA function in the immune system causes B cell abnormalities von Coppola, Vincenzo, Barrick, Colleen A, Southon, Eileen A, Celeste, Arkady, Wang, Kathryn, Chen, Bei, Haddad, El-Bdaoui, Yin, Jian, Nussenzweig, Andre, Subramaniam, Arun, Tessarollo, Lino

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Pathogen-Specific Loss of Host Resistance in Mice Lacking the IFN-γ -Inducible Gene IGTP von Taylor, Gregory A., Collazo, Carmen M., Yap, George S., Nguyen, Khuong, Gregorio, Theresa A., Taylor, Lynn S., Eagleson, Bryn, Secrest, Lisa, Southon, Eileen A., Reid, Susan W., Tessarollo, Lino, Bray, Mike, McVicar, Dan W., Komschlies, Kristin L., Young, Howard A., Biron, Christine A., Sher, Alan, George F. Vande Woude

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Protocol for the saturation and multiplexing of genetic variants using CRISPR-Cas9 von Sahu, Sounak, Sullivan, Teresa, Southon, Eileen, Caylor, Dylan, Geh, Josephine, Sharan, Shyam K.

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Manipulating Mouse Embryonic Stem Cells von Southon, Eileen, Tessarollo, Lino

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Kidney-Targeted Birt-Hogg-Dubé Gene Inactivation in a Mouse Model: Erk1/2 and Akt-mTOR Activation, Cell Hyperproliferation, and Polycystic Kidneys von Baba, Masaya, Furihata, Mutsuo, Hong, Seung-Beom, Tessarollo, Lino, Haines, Diana C., Southon, Eileen, Patel, Vishal, Igarashi, Peter, Alvord, W. Gregory, Leighty, Robert, Yao, Masahiro, Bernardo, Marcelino, Ileva, Lilia, Choyke, Peter, Warren, Michelle B., Zbar, Berton, Linehan, W. Marston, Schmidt, Laura S.

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